scholarly journals Novel metal ion surface modification technique

1991 ◽  
Vol 58 (13) ◽  
pp. 1392-1394 ◽  
Author(s):  
I. G. Brown ◽  
X. Godechot ◽  
K. M. Yu
1990 ◽  
Author(s):  
I.G. Brown ◽  
X. Godechot ◽  
K.M. Yu

1996 ◽  
Vol 83 (1-3) ◽  
pp. 280-283 ◽  
Author(s):  
Tonghe Zhang ◽  
Xiaoyan Wang ◽  
Hong Liang ◽  
Huixing Zhang ◽  
Gu Zhou ◽  
...  

2022 ◽  
Vol 131 (1) ◽  
pp. 014901
Author(s):  
Byeong Jun Cha ◽  
Woo Jun Byeon ◽  
Chang Min Choi ◽  
Boo Ki Min ◽  
Jinwan Cho ◽  
...  

2007 ◽  
Vol 201 (19-20) ◽  
pp. 8637-8640
Author(s):  
Alexander I. Ryabchikov ◽  
Igor B. Stepanov

2019 ◽  
Vol 6 (4) ◽  
pp. 231-240 ◽  
Author(s):  
Günnur Onak ◽  
Ozan Karaman

Abstract Surface modification by non-thermal atmospheric plasma (NTAP) treatment can produce significantly higher carboxylic groups on the nanofibers (NF) surface, which potentially can increase biomineralization of NF via promoting glutamic acid (GLU) templated peptide conjugation. Herein, electrospun poly(lactide-co-glycolide) (PLGA) scaffolds were treated with NTAP and conjugated with GLU peptide followed by incubation in simulated body fluids for mineralization. The effect of NTAP treatment and GLU peptide conjugation on mineralization, surface wettability and roughness were investigated. The results showed that NTAP treatment significantly increased GLU peptide conjugation which consequently enhanced mineralization and mechanical properties of NTAP treated and peptide conjugated NF (GLU-pNF) compared to neat PLGA NF, NTAP treated NF (pNF) and GLU peptide conjugated NF (GLU-NF). The effect of surface modification on human bone marrow derived mesenchymal stem cells adhesion, proliferation and morphology was evaluated by cell proliferation assay and fluorescent microscopy. Results demonstrated that cellular adhesion and proliferation were significantly higher on GLU-pNF compared to NF, pNF and GLU-NF. In summary, NTAP treatment could be a promising modification technique to induce biomimetic peptide conjugation and biomineralization for bone tissue engineering applications.


2012 ◽  
Vol 20 ◽  
pp. 21-31 ◽  
Author(s):  
Quinn K.T. Ng ◽  
Tatiana Segura ◽  
Anat Ben-Shlomo ◽  
Thomas Krause ◽  
Thomas L. Mindt ◽  
...  

The use of metal chelators is becoming increasingly important in the development of new tracers for molecular imaging. With the rise of the field of nanotechnology, the fusion of both technologies has shown great potential for clinical applications. The pharmacokinetcs of nanoparticles can be monitored via positron emission tomography (PET) after surface modification and radiolabeling with positron emitting radionuclides. Different metal ion chelators can be used to facilitate labeling of the radionuclides and as a prerequisite, optimized radiolabeling procedure is necessary to prevent nanoparticle aggregation and degradation. However, the effects of chelator modification on nanoparticle pharmacokinetic properties have not been well studied and currently no studies to date have compared the biological effects of the use of different chelators in the surface modification of nanoparticles.


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