The Molecular Basis of Streptococcal Toxic Shock Syndrome

2004 ◽  
Vol 350 (20) ◽  
pp. 2093-2094 ◽  
Author(s):  
Eric J. Brown
Keyword(s):  
Toxic Shock Syndrome ◽  
Molecular Basis ◽  
Streptococcal Toxic Shock Syndrome ◽  
Toxic Shock

Streptococcal toxic shock syndrome revealed phlegmasia cerulea dolens of the arm

2020 ◽  
Vol 20 (11) ◽  
pp. 1348
Author(s):  
Vivien Moris ◽  
David Guillier ◽  
Narcisse Zwetyenga ◽  
Eric Steinmetz
Keyword(s):  
Toxic Shock Syndrome ◽  
Streptococcal Toxic Shock Syndrome ◽  
Toxic Shock ◽  
Phlegmasia Cerulea Dolens

scholarly journals A Patient of Using Presepsin to Diagnose Streptococcal Toxic Shock Syndrome during Anticancer Drug Treatment

2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Gaku Takahashi
Keyword(s):  
Blood Culture ◽  
Toxic Shock Syndrome ◽  
Lower Leg ◽  
Rapid Progression ◽  
Streptococcal Toxic Shock Syndrome ◽  
Toxic Shock ◽  
Anticancer Chemotherapy ◽  
Successful Recovery ◽  
Short Period ◽  
Infection Focus

Background. Streptococcal toxic shock syndrome (STSS) is a rapidly progressive infection, with potentially rapid patient deterioration in a very short period. We experienced a rare case of STSS during anticancer chemotherapy, and we continuously measured presepsin (P-SEP) and evaluated its usefulness. Case Presentation. A 60-year-old woman with pulmonary metastasis from cervical cancer began anticancer chemotherapy. A fever of >40°C and right lower leg swelling developed on day 3. Symptoms worsened despite cefmetazole treatment (1.0 g/day). Blood culture was performed without suspecting STSS. On day 5, symptoms worsened and acute disseminated intravascular coagulation (DIC) and sequential organ failure assessment (SOFA) scores increased. C-reactive protein (CRP) increased from 28.8 mg/dl to 35.5 mg/dl and P-SEP also increased from 1,635 to 2,350 pg/mL. STSS was suspected due to the rapid progression of brown discoloration of the entire right lower leg. Ceftriaxone 2 g/day and clindamycin 1,200 mg/day were begun. On the evening of day 5, blood culture revealed rapidly progressive group A streptococci. After that, symptoms improved rapidly with treatment, and SOFA and DIC scores also decreased. While CRP remained at about 0.5 mg/dl, P-SEP remained slightly elevated at about 400 pg/mL. A residual infection focus was suspected. Contrast-enhanced computed tomography (CT) revealed a capsule-enclosed abscess in the right lower leg soleus muscle on day 32. Debridement was performed and antibiotics were continued until P-SEP was 88 pg/mL. CT confirmed the disappearance of the abscess. Conclusion. Prompt diagnosis by blood culture and a sufficiently early, appropriate change in antibiotic therapy led to successful recovery from STSS during anticancer chemotherapy without lower limb amputation. P-SEP was useful in assessment of the residual infection focus and suspending treatments.

scholarly journals Streptococcal toxic shock syndrome following total thyroidectomy

2013 ◽  
Vol 95 (7) ◽  
pp. 457-460 ◽  
Author(s):  
J AZ Hung ◽  
P Rajeev
Keyword(s):  
Total Thyroidectomy ◽  
Toxic Shock Syndrome ◽  
Cowden Syndrome ◽  
Streptococcal Toxic Shock Syndrome ◽  
Rare Occurrence ◽  
Toxic Shock ◽  
Group A ◽  
High Index Of Suspicion ◽  
Improve Patient ◽  
Management Issues

Group A streptococcal toxic shock syndrome following clean surgery is a rare occurrence. Its incidence following thyroid surgery has not been described in the literature. We report on the presentation and management of severe streptococcal toxic shock syndrome following a total thyroidectomy for a multinodular goitre in a patient with Cowden syndrome. This report presents an overview of streptococcal toxic shock syndrome with a focus on the management issues to consider so as to improve patient outcome. All surgeons must maintain a high index of suspicion for this rare but dangerous entity.

scholarly journals Capsule ofStreptococcus pyogenesIs Essential for Delayed Death of Mice in a Model of Streptococcal Toxic Shock Syndrome

2006 ◽  
Vol 50 (2) ◽  
pp. 127-130 ◽  
Author(s):  
Ken-ichiro Iida ◽  
Masanori Seki ◽  
Mitsumasa Saito ◽  
Yoshiaki Kawamura ◽  
Hideko Kajiwara ◽  
...  
Keyword(s):  
Toxic Shock Syndrome ◽  
Streptococcal Toxic Shock Syndrome ◽  
Toxic Shock ◽  
Delayed Death
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