Nonmedical Prescription-Opioid Use and Heroin Use

2016 ◽  
Vol 374 (13) ◽  
pp. 1295-1296 ◽  
Keyword(s):  
Prescription Opioid ◽  
Opioid Use ◽  
Heroin Use ◽  
Prescription Opioid Use

scholarly journals Association of Nonmedical Prescription Opioid Use With Subsequent Heroin Use Initiation in Adolescents

2019 ◽  
Vol 173 (9) ◽  
pp. e191750 ◽  
Author(s):  
Lorraine I. Kelley-Quon ◽  
Junhan Cho ◽  
David R. Strong ◽  
Richard A. Miech ◽  
Jessica L. Barrington-Trimis ◽  
...  
Keyword(s):  
Prescription Opioid ◽  
Opioid Use ◽  
Heroin Use ◽  
Prescription Opioid Use

scholarly journals Relationship between Nonmedical Prescription-Opioid Use and Heroin Use

2016 ◽  
Vol 374 (2) ◽  
pp. 154-163 ◽  
Author(s):  
Wilson M. Compton ◽  
Christopher M. Jones ◽  
Grant T. Baldwin
Keyword(s):  
Prescription Opioid ◽  
Opioid Use ◽  
Heroin Use ◽  
Prescription Opioid Use

scholarly journals Nonmedical Prescription Opioid Use in Childhood and Early Adolescence Predicts Transitions to Heroin Use in Young Adulthood: A National Study

2015 ◽  
Vol 167 (3) ◽  
pp. 605-612.e2 ◽  
Author(s):  
Magdalena Cerdá ◽  
Julián Santaella ◽  
Brandon D.L. Marshall ◽  
June H. Kim ◽  
Silvia S. Martins
Keyword(s):  
Young Adulthood ◽  
Early Adolescence ◽  
National Study ◽  
Prescription Opioid ◽  
Opioid Use ◽  
Heroin Use ◽  
Prescription Opioid Use

scholarly journals Adverse Childhood Experiences Predict Early Initiation of Opioid Use Behaviors

2021 ◽  
Vol 6 ◽  
Author(s):  
Honoria Guarino ◽  
Pedro Mateu-Gelabert ◽  
Kelly Quinn ◽  
Skultip Sirikantraporn ◽  
Kelly V. Ruggles ◽  
...  
Keyword(s):  
Substance Use ◽  
Adverse Childhood Experiences ◽  
Early Initiation ◽  
Prescription Opioid ◽  
Opioid Use ◽  
Medical Prescription ◽  
Childhood Experiences ◽  
Heroin Use ◽  
Adverse Childhood ◽  
Prescription Opioid Use

Introduction: Although a substantial body of research documents a relationship between traumatic stress in childhood and the initiation of substance use later in the life course, only limited research has examined potential linkages between adverse childhood experiences (ACEs) and the initiation of non-medical prescription opioid use and other opioid use behaviors. The present study contributes to this growing body of work by investigating the association of childhood trauma with early initiation of a series of opioid use behaviors.Methods: New York City young adults (n = 539) ages 18–29 who reported non-medical use of prescription opioids or heroin use in the past 30 days were recruited using Respondent-Driven Sampling in 2014–16. Ten ACEs were assessed via self-report with the ACE Questionnaire. Associations between number of ACEs and self-reported ages of initiating seven opioid use behaviors (e.g., non-medical prescription opioid use, heroin use, heroin injection) were estimated with multivariable logistic regression.Results: Eighty nine percent of participants reported at least one ACE, and 46% reported four or more ACEs, a well-supported threshold indicating elevated risk for negative health consequences. Every increase of one trauma was associated with a 12–23% increase in odds of early initiation across the seven opioid use behaviors. Findings also document that the mean age at initiation increased with increasing risk severity across the behaviors, contributing to evidence of a trajectory from opioid pill misuse to opioid injection.Discussion: Increasing number of childhood traumas was associated with increased odds of earlier initiation of multiple opioid misuse behaviors. In light of prior research linking earlier initiation of substance use with increased substance use severity, present findings suggest the importance of ACEs as individual-level determinants of increased opioid use severity. Efforts to prevent onset and escalation of opioid use among at-risk youth may benefit from trauma prevention programs and trauma-focused screening and treatment, as well as increased attention to ameliorating upstream socio-structural drivers of childhood trauma.

Patterns of heroin use following index prescription opioid exposure

2020 ◽  
Vol 16 (1) ◽  
pp. 49-57
Author(s):  
Scott M. Sexton, PharmD ◽  
Christopher M. Herndon, PharmD, BCACP ◽  
Jordan D. Sinclair, PharmD
Keyword(s):  
Primary Care Physicians ◽  
Outcome Measure ◽  
The United States ◽  
Prescription Opioid ◽  
Prescription Opioids ◽  
Opioid Use ◽  
Cross Sectional ◽  
Heroin Use ◽  
Chronic Pain Condition ◽  
Prescription Opioid Use

Objective: This study examined the means of obtainment, indication, and prescriber of an index opioid in self-reporting heroin users.Design: Cross-sectional, observational study.Setting: A survey was submitted by participants in the United States with current or past heroin use.Participants: Three hundred twenty-three participants greater than 18 years of age completed the survey.Main outcome measure: Participants were surveyed regarding prescription opioid use prior to heroin initiation and specifically how they were obtained. Surveys were comprehensive in nature, divulging information including which opioid(s) was/were used, how they were obtained, by which prescriber (if prescribed), and if there was a diagnosis for chronic pain.Results: Roughly 47 percent of participants reported using prescription opioids prior to heroin. The most commonly used prescription opioid prior to heroin initiation was oxycodone (92.5 percent). The most common acquisition of opioids was through the prescribing of a physician, which occurred in roughly 63 percent of cases. These prescriptions were obtained most often from primary care physicians and emergency departments. Only 34 percent of participants reported being diagnosed with a chronic pain condition prior to using heroin.Conclusions: This study further supports the role that prescription opioids play in the transition to heroin use. It suggests that oxycodone is the most common prescription opioid used prior to heroin initiation. Additionally, it reports descriptive information as to how and where prescription opioids are obtained. 

Analyzing the relationship between nonmedical prescription-opioid use and heroin use

2016 ◽  
Vol 12 (1) ◽  
pp. 11 ◽  
Author(s):  
Xiulu Ruan, MD ◽  
Melville Q. Wyche, III, MD ◽  
Alan David Kaye, MD, PhD
Keyword(s):  
Prescription Opioid ◽  
Opioid Use ◽  
Heroin Use ◽  
Prescription Opioid Use ◽  
The Relationship

No abstract

Risks associated with nonmedical prescription opioid use: Transition to heroin use and drug injection, overdose and hepatitis C

2015 ◽  
Vol 156 ◽  
pp. e141-e142
Author(s):  
Pedro Mateu-Gelabert ◽  
Honoria Guarino ◽  
Lauren Jessell ◽  
Cassandra Syckes ◽  
Samuel R. Friedman
Keyword(s):  
Hepatitis C ◽  
Prescription Opioid ◽  
Drug Injection ◽  
Opioid Use ◽  
Heroin Use ◽  
Prescription Opioid Use
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