Acyclovir Treatment of Primary Herpes in Pregnancy Complicated by Second Trimester Preterm Premature Rupture of Membranes with Term Delivery: Case Report

2002 ◽  
Vol 19 (5) ◽  
pp. 235-238 ◽  
Author(s):  
Yvonne M. Dietrich ◽  
Peter G. Napolitano
Keyword(s):  
Case Report ◽  
Second Trimester ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Preterm Premature Rupture ◽  
Acyclovir Treatment ◽  
Term Delivery ◽  
In Pregnancy

scholarly journals Obstetric Management of Copperhead Snake Envenomation in Pregnancy: A Case Report

2019 ◽  
Vol 2 (2) ◽  
pp. 35-41
Author(s):  
Michelle J. Wang ◽  
Michelle Y. Lu ◽  
Elizabeth B. Ausbeck ◽  
Lorie M. Harper
Keyword(s):  
Case Report ◽  
Preterm Labor ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Fetal Outcomes ◽  
Snake Envenomation ◽  
Preterm Premature Rupture ◽  
Antenatal Steroids ◽  
Obstetric Management ◽  
In Pregnancy

Snakebites in pregnancy can result in significant maternal and fetal harm; however, the literature to guide management of this rare obstetric complication remains limited. We describe our approach to envenomation in pregnancy based on the currently available evidence. A 27-year-old G2P1 female presented at 27 weeks’ gestation after suffering a copperhead snakebite. She received antivenom and antenatal steroids without adverse maternal or fetal event. Antenatal testing was reassuring throughout admission, and she was discharged home with plans for close outpatient surveillance. She later developed preterm premature rupture of membranes and preterm labor, with delivery of a live infant at 33 weeks’ gestation. The risk of adverse maternal and fetal outcomes following snake envenomation in pregnancy may warrant closer antenatal surveillance than has been previously described.

scholarly journals Prolonged SARS-CoV-2 Viral Shedding in Pregnancy and Risk of Extended inPatient Isolation: A Case Report

2020 ◽  
pp. 1-5
Author(s):  
Emad A Elsamadicy ◽  
Emad A Elsamadicy ◽  
Mary E Burgoyne ◽  
Naomi Hauser ◽  
Andrea Desai
Keyword(s):  
Case Report ◽  
Severe Acute Respiratory Syndrome ◽  
Healthcare Systems ◽  
Clinical Aspects ◽  
Negative Consequences ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Viral Shedding ◽  
Preterm Premature Rupture ◽  
In Pregnancy

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for coronavirus disease 2019 (COVID-19), continues to challenge healthcare systems worldwide, and further investigation is required to determine its effects on the pregnant population. Prolonged viral shedding (>15-33 days), especially without appropriate testing guidelines, can subject admitted patients to unnecessarily long isolation, which influences emotional, physical, and clinical aspects of their antepartum course. We report a young, primigravida Haitian female admitted to the antepartum service at 22 weeks of gestation with preterm premature rupture of membranes (PPROM), who remained admitted in isolation for over 6 weeks due to persistent positive SARS-CoV-2 testing. This case highlights the importance of establishing testing guidelines to prevent unnecessary isolation, which has negative consequences for patient care. There is an urgent need for updated guidelines for the duration of isolation based on the presence of the viable virus.

scholarly journals Docosahexaenoic Acid Supplementation Early in Pregnancy May Prevent Deep Placentation Disorders

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Jorge A. Carvajal
Keyword(s):  
Preterm Birth ◽  
Docosahexaenoic Acid ◽  
Fetal Growth ◽  
Fetal Growth Restriction ◽  
Preterm Labor ◽  
Growth Restriction ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Preterm Premature Rupture ◽  
In Pregnancy

Uteroplacental ischemia may cause preterm birth, either due to preterm labor, preterm premature rupture of membranes, or medical indication (in the presence of preeclampsia or fetal growth restriction). Uteroplacental ischemia is the product of defective deep placentation, a failure of invasion, and transformation of the spiral arteries by the trophoblast. The failure of normal placentation generates a series of clinical abnormalities nowadays called “deep placentation disorders”; they include preeclampsia, fetal growth restriction, preterm labor, preterm premature rupture of membranes, in utero fetal death, and placental abruption. Early reports suggested that a LC-PUFAs (long chain polyunsaturated fatty acids) rich diet reduces the incidence of deep placentation disorders. Recent randomized controlled trials are inconsistent to show the benefit of docosahexaenoic acid (DHA) supplementation during pregnancy to prevent deep placentation disorders, but most of them showed that DHA supplementation was associated with lower risk of early preterm birth. We postulate that DHA supplementation, early in pregnancy, may reduce the incidence of deep placentation disorders. If our hypothesis is correct, DHA supplementation, early in pregnancy, will become a safe and effective strategy for primary prevention of highly relevant pregnancy diseases, such as preterm birth, preeclampsia, and fetal growth restriction.

scholarly journals Klebsiella pneumoniae Chorioamnionitis: An Underrecognized Cause of Preterm Premature Rupture of Membranes in the Second Trimester

2021 ◽  
Vol 9 (1) ◽  
pp. 96
Author(s):  
Maria Paola Bonasoni ◽  
Andrea Palicelli ◽  
Giulia Dalla Dea ◽  
Giuseppina Comitini ◽  
Paola Nardini ◽  
...  
Keyword(s):  
Klebsiella Pneumoniae ◽  
Maternal Blood ◽  
Community Acquired Pneumonia ◽  
Etiologic Agent ◽  
Intestinal Lumen ◽  
Second Trimester ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Preterm Premature Rupture ◽  
Threatened Abortion

Klebsiella pneumoniae is a Gram-negative, rod-shaped bacterium, responsible for hospital and community acquired pneumonia, urinary tract and wound infections, and bloodstream dissemination. K. pneumoniae infection in pregnancy, leading to acute chorioamnionitis (AC), preterm premature rupture of membranes (PPROM) and early pregnancy loss in the second trimester, has been rarely reported. Herein, we present a case of K. pneumoniae AC that caused intrauterine fetal demise (IUFD) at 19 weeks + 5 days. The 36-year-old mother was admitted at 18 weeks + 1 day of gestation for threatened abortion. IUFD occurred 11 days after. Fetal postmortem showed severe AC and funisitis, neutrophils within alveoli and intestinal lumen, associated with rod-like bacteria. Fetal blood and lung cultures grew K. pneumoniae, β-lactamase-non-producing strain. Antibiogram revealed sensitivity for piperacillin/tazobactam. Three days after IUFD, the mother presented with fever (37.8 °C) which persisted for one week. Maternal blood and urine cultures were negative. According to fetal microbiological results, available 6 days after IUFD, initial treatment with amoxicillin/clavulanic acid was replaced with piperacillin/tazobactam with full patient recovery. Therefore, in the event of PPROM and IUFD, fetal microbiological investigations should always be performed to isolate the proper etiologic agent and start the correct medical treatment.

scholarly journals Second Trimester Fetal Loss Due to Citrobacter koseri Infection: A Rare Cause of Preterm Premature Rupture of Membranes (PPROM)

Diagnostics ◽  
2022 ◽  
Vol 12 (1) ◽  
pp. 159
Author(s):  
Maria Paola Bonasoni ◽  
Giuseppina Comitini ◽  
Mariangela Pati ◽  
Giuseppe Russello ◽  
Loredana Vizzini ◽  
...  
Keyword(s):  
Fetal Loss ◽  
Second Trimester ◽  
Maternal Transmission ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Preterm Premature Rupture ◽  
Abdominal Organs ◽  
First Case ◽  
The Family ◽  
Severe Infections

Citrobacter koseri is a facultative anaerobic, motile, non-spore-forming Gram-negative bacillus, which belongs to the family of Enterobacteriaceae. Severe infections due to Citrobacter spp. have been reported in the urinary tract, respiratory airways, intra-abdominal organs, skin and soft tissue, eye, bone, bloodstream, and central nervous system. In newborns, C. koseri is a well-known cause of meningitis, cerebral abscesses, brain adhesions, encephalitis, and pneumocephalus. Infection can be acquired through vertical maternal transmission or horizontal hospital settings; however, in many cases, the source is unknown. Preterm premature rupture of membranes (PPROM), caused by C. koseri, has rarely been described. Herein, we describe a case of PPROM at 16 weeks and 3 days of gestation, leading to anhydramnios. The parents opted for legal termination of the pregnancy, as the prognosis was very poor. C. koseri was isolated postmortem from a placental subamniotic swab and parenchymal sample, as well as fetal blood and lung. To the best of our knowledge, this is the first case of early second-trimester PPROM in which C. koseri infection was demonstrated.

scholarly journals Fetal head entrapment within the lower uterine segment

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Ariel T. Levy ◽  
Melissa A. Yurkanin ◽  
Lauren A. Plante
Keyword(s):  
Cesarean Section ◽  
Growth Restriction ◽  
Lower Uterine Segment ◽  
Obstetric Complication ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Fetal Head ◽  
Preterm Premature Rupture ◽  
Uterine Scar ◽  
In Pregnancy

AbstractFetal head entrapment by a uterine scar or adhesion is a rare obstetric complication. We present a case of a uterine constriction diagnosed in pregnancy that resulted in confinement of the fetal head to the lower uterine segment. The developing fetus ultimately suffered growth restriction of the head and was delivered after the mother experienced preterm premature rupture of membranes (PROM). Severe adhesions of the lower uterine segment were confirmed during the patient’s classical cesarean section.

scholarly journals A Complicated Case of Acute Promyelocytic Leukemia in the Second Trimester of Pregnancy Successfully Treated with All-trans-Retinoic Acid

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Kanika Agarwal ◽  
Megha Patel ◽  
Vandana Agarwal
Keyword(s):  
Retinoic Acid ◽  
Acute Promyelocytic Leukemia ◽  
Breech Presentation ◽  
Promyelocytic Leukemia ◽  
Second Trimester ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Preterm Premature Rupture ◽  
Trans Retinoic Acid ◽  
All Trans Retinoic Acid

A 40-year-old female at 26-week gestation was diagnosed with acute promyelocytic leukemia (APL) after an abnormal prenatal lab workup showed pancytopenia. She was treated with all-trans-retinoic acid (ATRA), idarubicin, and dexamethasone. After day one of treatment, she developed differentiation syndrome, which was treated with dexamethasone. At 30-week gestation, she had preterm premature rupture of membranes and delivered by cesarean section because of the fetus’ breech presentation. Despite ATRA’s potential for teratogenicity, a viable infant was born without apparent anomalies. Postpartum, she underwent consolidation treatment with ATRA and arsenic trioxide (ATO). The patient continued ATRA therapy after delivery and is currently in remission.

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