Dynamic Resolution of α-Bromo-α-Alkyl Esters Using N-Methyl Pseudo-ephedrine as a Chiral Auxiliary: Asymmetric Syntheses of α-Amino Acid Derivatives

Synlett ◽  
2002 ◽  
Vol 2002 (05) ◽  
pp. 0790-0792 ◽  
Author(s):  
Sang-kuk Lee ◽  
Jiyoun Nam ◽  
Yong Sun Park
Keyword(s):  
Amino Acid ◽  
Chiral Auxiliary ◽  
Amino Acid Derivatives ◽  
Alkyl Esters ◽  
Asymmetric Syntheses ◽  
Dynamic Resolution

scholarly journals Substrate-controlled Diastereoselective Michael Addition of Alkylidene Malonates by Grignard Reagents

2019 ◽  
Vol 25 (1) ◽  
pp. 116-121
Author(s):  
Wei Zhou ◽  
Qingwei Xiao ◽  
Yuanyuan Chang ◽  
Qifa Liu ◽  
Xiaohao Zang ◽  
...  
Keyword(s):  
Amino Acid ◽  
Asymmetric Synthesis ◽  
Michael Addition ◽  
Chiral Auxiliary ◽  
Grignard Reagents ◽  
Amino Acid Derivatives ◽  
Catalyst Free ◽  
Chemical Efficiency

AbstractHerein is described a diastereoselective Michael addition of Grignard reagents to α, β- unsaturated diethyl malonates incorporated with a 2-oxazolidone chiral auxiliary. The catalyst-free Michael addition proceeds with good chemical efficiency and excellent stereoselectivity; and it provides new thoughts to the asymmetric synthesis of β-substituted β3 amino acid derivatives.

Preparation ofβ2-Amino Acid Derivatives (β2hThr,β2hTrp,β2hMet,β2hPro,β2hLys, Pyrrolidine-3-carboxylic Acid) by Using DIOZ as Chiral Auxiliary

2005 ◽  
Vol 88 (8) ◽  
pp. 2235-2250 ◽  
Author(s):  
Francois Gessier ◽  
Laurent Schaeffer ◽  
Thierry Kimmerlin ◽  
Oliver Flögel ◽  
Dieter Seebach
Keyword(s):  
Amino Acid ◽  
Carboxylic Acid ◽  
Chiral Auxiliary ◽  
Amino Acid Derivatives

scholarly journals 1-(2,4,6-Triisopropylphenyl)ethylamine: A New Chiral Auxiliary for the Asymmetric Synthesis of γ-Amino Acid Derivatives.

ChemInform ◽  
2007 ◽  
Vol 38 (21) ◽  
Author(s):  
Pascale Cividino ◽  
Sandrine Py ◽  
Philippe Delair ◽  
Andrew E. Greene
Keyword(s):  
Amino Acid ◽  
Asymmetric Synthesis ◽  
Chiral Auxiliary ◽  
Amino Acid Derivatives

Diastereoselective Synthesis of β-Heteroaryl syn-α-Methyl-β-Amino Acid Derivatives via a Double Chiral Auxiliary Approach

2013 ◽  
Vol 15 (3) ◽  
pp. 562-565 ◽  
Author(s):  
Jianwei Bian ◽  
David Blakemore ◽  
Joseph S. Warmus ◽  
Jianmin Sun ◽  
Matthew Corbett ◽  
...  
Keyword(s):  
Amino Acid ◽  
Chiral Auxiliary ◽  
Amino Acid Derivatives ◽  
Diastereoselective Synthesis

ChemInform Abstract: Asymmetric Syntheses of α-Methyl γ-Amino Acid Derivatives.

ChemInform ◽  
2011 ◽  
Vol 43 (4) ◽  
pp. no-no
Author(s):  
Ye Zhu ◽  
Sakunchai Khumsubdee ◽  
Amber Schaefer ◽  
Kevin Burgess
Keyword(s):  
Amino Acid ◽  
Amino Acid Derivatives ◽  
Asymmetric Syntheses

1-(2,4,6-Triisopropylphenyl)ethylamine:  A New Chiral Auxiliary for the Asymmetric Synthesis of γ-Amino Acid Derivatives

2007 ◽  
Vol 72 (2) ◽  
pp. 485-493 ◽  
Author(s):  
Pascale Cividino ◽  
Sandrine Py ◽  
Philippe Delair ◽  
Andrew E. Greene
Keyword(s):  
Amino Acid ◽  
Asymmetric Synthesis ◽  
Chiral Auxiliary ◽  
Amino Acid Derivatives

ChemInform Abstract: ELECTROPHILIC ASYMMETRIC SYNTHESES OF α-AMINO ACID DERIVATIVES

1984 ◽  
Vol 15 (34) ◽  
Author(s):  
K. G. DAVENPORT ◽  
D. T. MAO ◽  
C. M. RICHMOND ◽  
D. E. BERGBREITER ◽  
M. NEWCOMB
Keyword(s):  
Amino Acid ◽  
Amino Acid Derivatives ◽  
Asymmetric Syntheses

Asymmetric Syntheses of α-Methyl γ-Amino Acid Derivatives

2011 ◽  
Vol 76 (18) ◽  
pp. 7449-7457 ◽  
Author(s):  
Ye Zhu ◽  
Sakunchai Khumsubdee ◽  
Amber Schaefer ◽  
Kevin Burgess
Keyword(s):  
Amino Acid ◽  
Amino Acid Derivatives ◽  
Asymmetric Syntheses
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