Release of β-Endorphin by Prostaglandin E2 to Lower Plasma Glucose in Streptozotocin-Induced Diabetic Rats

2001 ◽  
Vol 33 (7) ◽  
pp. 439-443 ◽  
Author(s):  
J. T. Cheng ◽  
I. M. Liu ◽  
T. C. Chi ◽  
T. F. Tzeng
Keyword(s):  
Prostaglandin E2 ◽  
Plasma Glucose ◽  
Diabetic Rats ◽  
Lower Plasma ◽  
Lower Plasma Glucose

Mediation of β-Endorphin by Ginsenoside Rh2 to Lower Plasma Glucose in Streptozotocin-Induced Diabetic Rats

Planta Medica ◽  
2006 ◽  
Vol 72 (1) ◽  
pp. 9-13 ◽  
Author(s):  
Dar-Ming Lai ◽  
Yong-Kwang Tu ◽  
I-Min Liu ◽  
Pei-Feng Chen ◽  
Juei-Tang Cheng
Keyword(s):  
Plasma Glucose ◽  
Diabetic Rats ◽  
Ginsenoside Rh2 ◽  
Lower Plasma ◽  
Lower Plasma Glucose

Activation of opioid μ-receptor by loperamide to lower plasma glucose in streptozotocin-induced diabetic rats

1999 ◽  
Vol 265 (3) ◽  
pp. 183-186 ◽  
Author(s):  
I.-Min Liu ◽  
Tzong-Cherng Chi ◽  
Yun Chueh Chen ◽  
Feng-Hwa Lu ◽  
Juei-Tang Cheng
Keyword(s):  
Plasma Glucose ◽  
Diabetic Rats ◽  
Lower Plasma ◽  
Lower Plasma Glucose ◽  
Μ Receptor

Myricetin as the Active Principle ofAbelmoschus moschatusto Lower Plasma Glucose in Streptozotocin-Induced Diabetic Rats

Planta Medica ◽  
2005 ◽  
Vol 71 (7) ◽  
pp. 617-621 ◽  
Author(s):  
I-Min Liu ◽  
Shorong-Shii Liou ◽  
Ting-Wei Lan ◽  
Feng-Lin Hsu ◽  
Juei-Tang Cheng
Keyword(s):  
Plasma Glucose ◽  
Diabetic Rats ◽  
Active Principle ◽  
Lower Plasma ◽  
Lower Plasma Glucose

Metformin can Activate Imidazoline I-2 Receptors to Lower Plasma Glucose in Type 1-like Diabetic Rats

2010 ◽  
Vol 43 (01) ◽  
pp. 26-30 ◽  
Author(s):  
J.-P. Lee ◽  
W. Chen ◽  
H.-T. Wu ◽  
K.-C. Lin ◽  
J.-T. Cheng
Keyword(s):  
Plasma Glucose ◽  
Diabetic Rats ◽  
Lower Plasma ◽  
Lower Plasma Glucose

scholarly journals Evaluation ofα-Glucosidase Inhibitory Effect of 50% Ethanolic Standardized Extract ofOrthosiphon stamineusBenth in Normal and Streptozotocin-Induced Diabetic Rats

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Elsnoussi Ali Mohamed ◽  
Mariam Ahmad ◽  
Lee Fung Ang ◽  
Mohd. Zaini Asmawi ◽  
Mun Fei Yam
Keyword(s):  
Plasma Glucose ◽  
Inhibitory Activity ◽  
Ethanolic Extract ◽  
Inhibitory Effect ◽  
Diabetic Rats ◽  
Lower Plasma ◽  
Antidiabetic Effect ◽  
Glucose Levels ◽  
Lower Plasma Glucose

In the present study, a 50% ethanolic extract ofOrthosiphon stamineuswas tested for itsα-glucosidase inhibitory activity.In vivoassays of the extract (containing 1.02%, 3.76%, and 3.03% of 3′hydroxy-5,6,7,4′-tetramethoxyflavone, sinensetin, and eupatorin, resp.) showed that it possessed an inhibitory activity againstα-glucosidase in normal rats loaded with starch and sucrose. The results showed that 1000 mg/kg of the 50% ethanolic extract ofO. stamineussignificantly (P<0.05) decreased the plasma glucose levels of the experimental animals in a manner resembling the effect of acarbose. In streptozotocin-induced diabetic rats, only the group treated with 1000 mg/kg of the extract showed significantly (P<0.05) lower plasma glucose levels after starch loading. Hence,α-glucosidase inhibition might be one of the mechanisms by whichO. stamineusextract exerts its antidiabetic effect. Furthermore, our findings indicated that the 50% ethanolic extract ofO. stamineuscan be considered as a potential agent for the management of diabetes mellitus.

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