Role of antibiotic prophylaxis for wound infection in percutaneous endoscopic gastrostomy (PEG): result of a prospective double-blind randomized trial

2002 ◽  
Vol 50 (4) ◽  
pp. 312-315 ◽  
Author(s):  
H. Panigrahi ◽  
D.R. Shreeve ◽  
W.C. Tan ◽  
R. Prudham ◽  
R. Kaufman
Keyword(s):  
Antibiotic Prophylaxis ◽  
Wound Infection ◽  
Randomized Trial ◽  
Percutaneous Endoscopic Gastrostomy ◽  
Double Blind ◽  
Endoscopic Gastrostomy

One-dose antibiotic prophylaxis against wound infection after appendicectomy: A randomized trial of clindamycin, cefazolin sodium and a placebo

1979 ◽  
Vol 66 (3) ◽  
pp. 193-196 ◽  
Author(s):  
I. A. Donovan ◽  
D. Ellis ◽  
D. Gatehouse ◽  
G. Little ◽  
R. Grimley ◽  
...  
Keyword(s):  
Antibiotic Prophylaxis ◽  
Wound Infection ◽  
Randomized Trial ◽  
Cefazolin Sodium

scholarly journals Effect of a single preoperative dose of oral antibiotic to reduce the incidence of surgical site infection following below-knee dermatological flap and graft repair

2019 ◽  
pp. 28-35 ◽  
Author(s):  
Helena Rosengren ◽  
Clare Heal ◽  
Petra Buettner
Keyword(s):  
Surgical Site Infection ◽  
Antibiotic Prophylaxis ◽  
Controlled Trial ◽  
Study Groups ◽  
High Dose ◽  
Antibiotic Administration ◽  
Oral Antibiotic ◽  
Site Infection ◽  
Double Blind

Background: Surgical site infection (SSI) rates for below-knee dermatological surgery are unacceptably high, particularly following complex flap and graft closures. The role of antibiotic prophylaxis for these surgical cases is uncertain. Objective: To determine whether SSI following complex dermatological closures on the leg could be reduced by antibiotic prophylaxis administered as a single oral preoperative dose. Methods: A total of 115 participants were randomized to 2 g of oral cephalexin or placebo 40-60 minutes prior to surgical incision in a prospective, randomized, double-blind, placebo-controlled trial at a primary care skin cancer clinic in North Queensland, Australia. Results: Overall 17/55 (30.9%) controls and 14/55 (25.5%) intervention participants developed infection (P = 0.525). There was no difference between the study groups in adverse symptoms that could be attributed to high-dose antibiotic administration (P = 1).

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