scholarly journals Cold ischemia decreases liver regeneration after partial liver transplantation in the rat: A TNF-α/IL-6-dependent mechanism

Hepatology ◽  
2002 ◽  
Vol 36 (4) ◽  
pp. 812-818 ◽  
Author(s):  
Nazia Selzner ◽  
Markus Selzner ◽  
Yinghua Tian ◽  
Zakiyah Kadry ◽  
Pierre-Alain Clavien
Keyword(s):  
Liver Transplantation ◽  
Liver Regeneration ◽  
Cold Ischemia ◽  
Partial Liver Transplantation ◽  
Tnf Α ◽  
Dependent Mechanism

Influence of cold ischemia on liver regeneration after partial liver transplantation

2002 ◽  
Vol 34 (6) ◽  
pp. 2303-2304 ◽  
Author(s):  
O Dirsch ◽  
U Dahmen ◽  
Y.L Gu ◽  
K Shen ◽  
J Li ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Liver Regeneration ◽  
Cold Ischemia ◽  
Partial Liver Transplantation

scholarly journals Platelets stimulate liver regeneration in a rat model of partial liver transplantation

2020 ◽  
Author(s):  
Chen Liang ◽  
Kazuhiro Takahashi ◽  
Kinji Furuya ◽  
Tatsuya Oda ◽  
Nobuhiro Ohkohchi
Keyword(s):  
Liver Transplantation ◽  
Liver Regeneration ◽  
Rat Model ◽  
Partial Liver Transplantation

scholarly journals Liver Regeneration after Hepatectomy and Partial Liver Transplantation

2020 ◽  
Vol 21 (21) ◽  
pp. 8414
Author(s):  
Shintaro Yagi ◽  
Masaaki Hirata ◽  
Yosuke Miyachi ◽  
Shinji Uemoto
Keyword(s):  
Liver Transplantation ◽  
Liver Injury ◽  
Liver Regeneration ◽  
Drug Induced ◽  
Venous Flow ◽  
Tissue Ischemia ◽  
Drug Induced Liver Injury ◽  
Partial Liver Transplantation ◽  
Clinical Conditions ◽  
Distinct Features

The liver is a unique organ with an abundant regenerative capacity. Therefore, partial hepatectomy (PHx) or partial liver transplantation (PLTx) can be safely performed. Liver regeneration involves a complex network of numerous hepatotropic factors, cytokines, pathways, and transcriptional factors. Compared with liver regeneration after a viral- or drug-induced liver injury, that of post-PHx or -PLTx has several distinct features, such as hemodynamic changes in portal venous flow or pressure, tissue ischemia/hypoxia, and hemostasis/platelet activation. Although some of these changes also occur during liver regeneration after a viral- or drug-induced liver injury, they are more abrupt and drastic following PHx or PLTx, and can thus be the main trigger and driving force of liver regeneration. In this review, we first provide an overview of the molecular biology of liver regeneration post-PHx and -PLTx. Subsequently, we summarize some clinical conditions that negatively, or sometimes positively, interfere with liver regeneration after PHx or PLTx, such as marginal livers including aged or fatty liver and the influence of immunosuppression.

scholarly journals Impact of cold ischemia on cytokines after partial liver transplantation in rats

2013 ◽  
Vol 12 (3) ◽  
pp. 4003-4008 ◽  
Author(s):  
Q.-A. Qi ◽  
Z.-Y. Yang ◽  
K.-S. Ma ◽  
Q. Lu ◽  
S.-G. Wang ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Cold Ischemia ◽  
Partial Liver Transplantation

scholarly journals TNF-α Induces Epithelial–Mesenchymal Transition of Renal Cell Carcinoma Cells via a GSK3β-Dependent Mechanism

2012 ◽  
Vol 10 (8) ◽  
pp. 1109-1119 ◽  
Author(s):  
Ming-Yi Ho ◽  
Shye-Jye Tang ◽  
Mei-Jen Chuang ◽  
Tai-Lung Cha ◽  
Jing-Yao Li ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Epithelial Mesenchymal Transition ◽  
Carcinoma Cells ◽  
Mesenchymal Transition ◽  
Tnf Α ◽  
Dependent Mechanism
Sign in / Sign up

Export Citation Format

Share Document