scholarly journals Assessment of Vessel Wall Thickness in Carotid Atherosclerosis using Spiral CT Angiography

2002 ◽  
Vol 23 (5) ◽  
pp. 437-440 ◽  
Author(s):  
C. Porsche ◽  
L. Walker ◽  
A.D. Mendelow ◽  
D. Birchall
Keyword(s):  
Ct Angiography ◽  
Wall Thickness ◽  
Vessel Wall ◽  
Carotid Atherosclerosis ◽  
Spiral Ct ◽  
Vessel Wall Thickness ◽  
Spiral Ct Angiography

Circle of Willis: evaluation with spiral CT angiography, MR angiography, and conventional angiography.

Radiology ◽  
1995 ◽  
Vol 195 (2) ◽  
pp. 445-449 ◽  
Author(s):  
D A Katz ◽  
M P Marks ◽  
S A Napel ◽  
P M Bracci ◽  
S L Roberts
Keyword(s):  
Ct Angiography ◽  
Mr Angiography ◽  
Spiral Ct ◽  
Circle Of Willis ◽  
Conventional Angiography ◽  
Spiral Ct Angiography

Dose reduction in spiral CT angiography of thoracic outlet syndrome by anatomically adapted tube current modulation

2001 ◽  
Vol 11 (4) ◽  
pp. 590-596 ◽  
Author(s):  
I. Mastora ◽  
M. Remy-Jardin ◽  
C. Suess ◽  
C. Scherf ◽  
J.-P. Guillot ◽  
...  
Keyword(s):  
Dose Reduction ◽  
Ct Angiography ◽  
Thoracic Outlet Syndrome ◽  
Spiral Ct ◽  
Tube Current Modulation ◽  
Current Modulation ◽  
Tube Current ◽  
Spiral Ct Angiography

Complete pre-operative imaging assessment of abdominal aortic aneurysm with spiral CT angiography

1997 ◽  
Vol 52 (5) ◽  
pp. 369-377 ◽  
Author(s):  
M.L. Errington ◽  
J.M. Ferguson ◽  
I.N. Gillespie ◽  
H.M. Connell ◽  
C.V. Ruckley ◽  
...  
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Ct Angiography ◽  
Spiral Ct ◽  
Abdominal Aortic ◽  
Spiral Ct Angiography

scholarly journals A neutralizing IL-11 antibody reduces vessel hyperplasia in a mouse carotid artery wire injury model

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
David Schumacher ◽  
Elisa A. Liehn ◽  
Pakhwan Nilcham ◽  
David Castaño Mayan ◽  
Chutima Rattanasopa ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Wall Thickness ◽  
Vessel Wall ◽  
Neointimal Hyperplasia ◽  
Endothelial Injury ◽  
Collagen Content ◽  
Arterial Stenosis ◽  
Matrix Metalloproteinase 2 ◽  
Vessel Wall Thickness ◽  
Artery Disease

AbstractVascular restenosis remains a major problem in patients with coronary artery disease (CAD) and peripheral artery disease (PAD). Neointimal hyperplasia, defined by post-procedure proliferation and migration of vascular smooth muscle cells (VSMCs) is a key underlying pathology. Here we investigated the role of Interleukin 11 (IL-11) in a mouse model of injury-related plaque development. Apoe−/− mice were fed a hyperlipidaemic diet and subjected to carotid wire injury of the right carotid. Mice were injected with an anti-IL11 antibody (X203), IgG control antibody or buffer. We performed ultrasound analysis to assess vessel wall thickness and blood velocity. Using histology and immunofluorescence approaches, we determined the effects of IL-11 inhibition on VSMC and macrophages phenotypes and fibrosis. Treatment of mice with carotid wire injury using X203 significantly reduced post-endothelial injury vessel wall thickness, and injury-related plaque, when compared to control. Immunofluorescence staining of the injury-related plaque showed that X203 treatment did not reduce macrophage numbers, but reduced the number of VSMCs and lowered matrix metalloproteinase 2 (MMP2) levels and collagen content in comparison to control. X203 treatment was associated with a significant increase in smooth muscle protein 22α (SM22α) positive cells in injury-related plaque compared to control, suggesting preservation of the contractile VSMC phenotype. Interestingly, X203 also reduced the collagen content of uninjured carotid arteries as compared to IgG, showing an additional effect on hyperlipidemia-induced arterial remodeling in the absence of mechanical injury. Therapeutic inhibition of IL-11 reduced vessel wall thickness, attenuated neointimal hyperplasia, and has favorable effects on vascular remodeling following wire-induced endothelial injury. This suggests IL-11 inhibition as a potential novel therapeutic approach to reduce arterial stenosis following revascularization in CAD and PAD patients.

Atherosclerosis: Carotid vessel wall thickness and aortic stiffness compared to stenosis class in peripheral arterial disease

2013 ◽  
Vol 24 ◽  
pp. e38-e39
Author(s):  
Harrie CM van den Bosch ◽  
Jos JM Westenberg ◽  
Wikke Setz-Pels ◽  
Alette Daniels-Gooszen ◽  
Lucien EM Duijm ◽  
...  
Keyword(s):  
Peripheral Arterial Disease ◽  
Wall Thickness ◽  
Vessel Wall ◽  
Aortic Stiffness ◽  
Arterial Disease ◽  
Vessel Wall Thickness ◽  
Carotid Vessel Wall ◽  
Peripheral Arterial ◽  
Carotid Vessel
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