scholarly journals A spatial hazard model for cluster detection on continuous indicators of disease: application to somatic cell score

2007 ◽  
Vol 38 (4) ◽  
pp. 585-596 ◽  
Author(s):  
Emilie Gay ◽  
Rachid Senoussi ◽  
Jacques Barnouin
Keyword(s):  
Somatic Cell ◽  
Hazard Model ◽  
Somatic Cell Score ◽  
Cluster Detection ◽  
Spatial Hazard

Relationship between somatic cell score and longevity of Holstein cows in Brazil using a piecewise Weibull proportional-hazard model

2019 ◽  
Vol 59 (8) ◽  
pp. 1546
Author(s):  
Elisandra Lurdes Kern ◽  
Jaime Araujo Cobuci ◽  
José Braccini Neto ◽  
Darlene dos Santos Daltro
Keyword(s):  
Somatic Cell ◽  
Milk Production ◽  
Hazard Model ◽  
Somatic Cell Score ◽  
Holstein Cows ◽  
Independent Effect ◽  
Proportional Hazard ◽  
Proportional Hazard Model ◽  
Weibull Proportional Hazard ◽  
The Impact

The objective of the present work was to evaluate the effect of somatic cell score on the longevity of Holstein cows raised all over Brazil, using a piecewise Weibull proportional-hazard model. The following two longevity traits were defined: true longevity, number of days from first calving to culling; and functional longevity, approximated by correcting true longevity to within-herd-year production. Records on productive life of 131330 cows were used. The model included the time-independent effect of age at first calving. The other effects were time-dependent, and included the following: region by year of calving, variation in herd-size class, milk-production class by year of calving within herd, within-herd milk-production class by number of lactations, within-herd fat content, within-herd protein content, and somatic cell score (SCS). The overall mean of the somatic cell counts (SCC) was 322000 cells/mL. The highest SCC mean was found between 130 to 290 days of lactation. The SCC mean decreased over the years. Cows from Region 5 (Rio Grande do Sul) showed higher SCC means. The risk of culling was slightly higher for functional longevity than for true longevity. The impact of longevity was high in cows from first to fourth lactation with a high SCS, with the risk of culling varying from 0.90 (true longevity: second lactation and Class 2) to 1.2 (functional longevity: fourth lactation and Class 5). Cows at the fifth lactation with a lower SCS had a higher risk of culling (1.4). Including the effect of SCS class by stage of lactation in the models was not beneficial. The decrease in SCS, especially from the first to fourth lactation, can be used for indirect selection to improve the longevity of Holstein cows in Brazil.

scholarly journals Analyses of the genetic relationships between lactose, somatic cell score, and growth traits in Simmental cattle

animal ◽  
2021 ◽  
pp. 100027
Author(s):  
C. Wei ◽  
H.-P. Luo ◽  
Y.-C. Wang ◽  
X.-X. Huang ◽  
M.-H. Zhang ◽  
...  
Keyword(s):  
Somatic Cell ◽  
Growth Traits ◽  
Genetic Relationships ◽  
Somatic Cell Score ◽  
Simmental Cattle

scholarly journals Feeding a Saccharomyces cerevisiae fermentation product improves udder health and immune response to a Streptococcus uberis mastitis challenge in mid-lactation dairy cows

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
M. Vailati-Riboni ◽  
D. N. Coleman ◽  
V. Lopreiato ◽  
A. Alharthi ◽  
R. E. Bucktrout ◽  
...  
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Somatic Cell ◽  
Pathway Analysis ◽  
Molecular Mechanisms ◽  
Somatic Cell Score ◽  
Molecular Networks ◽  
Epithelial Tissue ◽  
Udder Health ◽  
Streptococcus Uberis ◽  
Fermentation Product

Abstract Background We aimed to characterize the protective effects and the molecular mechanisms of action of a Saccharomyces cerevisiae fermentation product (NTK) in response to a mastitis challenge. Eighteen mid-lactation multiparous Holstein cows (n = 9/group) were fed the control diet (CON) or CON supplemented with 19 g/d NTK for 45 d (phase 1, P1) and then infected in the right rear quarter with 2500 CFU of Streptococcus uberis (phase 2, P2). After 36-h, mammary gland and liver biopsies were collected and antibiotic treatment started until the end of P2 (9 d post challenge). Cows were then followed until day 75 (phase 3, P3). Milk yield (MY) and dry matter intake (DMI) were recorded daily. Milk samples for somatic cell score were collected, and rectal and udder temperature, heart and respiration rate were recorded during the challenge period (P2) together with blood samples for metabolite and immune function analyses. Data were analyzed by phase using the PROC MIXED procedure in SAS. Biopsies were used for transcriptomic analysis via RNA-sequencing, followed by pathway analysis. Results DMI and MY were not affected by diet in P1, but an interaction with time was recorded in P2 indicating a better recovery from the challenge in NTK compared with CON. NTK reduced rectal temperature, somatic cell score, and temperature of the infected quarter during the challenge. Transcriptome data supported these findings, as NTK supplementation upregulated mammary genes related to immune cell antibacterial function (e.g., CATHL4, NOS2), epithelial tissue protection (e.g. IL17C), and anti-inflammatory activity (e.g., ATF3, BAG3, IER3, G-CSF, GRO1, ZFAND2A). Pathway analysis indicated upregulation of tumor necrosis factor α, heat shock protein response, and p21 related pathways in the response to mastitis in NTK cows. Other pathways for detoxification and cytoprotection functions along with the tight junction pathway were also upregulated in NTK-fed cows. Conclusions Overall, results highlighted molecular networks involved in the protective effect of NTK prophylactic supplementation on udder health during a subclinical mastitic event.

scholarly journals Genomic prediction of lactation curves for milk, fat, protein, and somatic cell score in Holstein cattle

2019 ◽  
Vol 102 (1) ◽  
pp. 452-463 ◽  
Author(s):  
H.R. Oliveira ◽  
L.F. Brito ◽  
F.F. Silva ◽  
D.A.L. Lourenco ◽  
J. Jamrozik ◽  
...  
Keyword(s):  
Somatic Cell ◽  
Genomic Prediction ◽  
Milk Fat ◽  
Somatic Cell Score ◽  
Holstein Cattle

scholarly journals Economic weights of somatic cell score in dairy sheep

animal ◽  
2007 ◽  
Vol 1 (2) ◽  
pp. 205-212 ◽  
Author(s):  
A. Legarra ◽  
M. Ramón ◽  
E. Ugarte ◽  
M.D. Pérez-Guzmán ◽  
J. Arranz
Keyword(s):  
Somatic Cell ◽  
Somatic Cell Score ◽  
Dairy Sheep ◽  
Economic Weights
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