scholarly journals Exploiting real-time FPGA based adaptive systems technology for real-time sensor fusion in next generation automotive safety systems

Author(s):  
S. Chappell ◽  
A. Macarthur ◽  
D. Preston ◽  
D. Olmstead ◽  
B. Flint ◽  
...  
Pathogens ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 461
Author(s):  
Madjid Morsli ◽  
Quentin Kerharo ◽  
Jeremy Delerce ◽  
Pierre-Hugues Roche ◽  
Lucas Troude ◽  
...  

Current routine real-time PCR methods used for the point-of-care diagnosis of infectious meningitis do not allow for one-shot genotyping of the pathogen, as in the case of deadly Haemophilus influenzae meningitis. Real-time PCR diagnosed H. influenzae meningitis in a 22-year-old male patient, during his hospitalisation following a more than six-metre fall. Using an Oxford Nanopore Technologies real-time sequencing run in parallel to real-time PCR, we detected the H. influenzae genome directly from the cerebrospinal fluid sample in six hours. Furthermore, BLAST analysis of the sequence encoding for a partial DUF417 domain-containing protein diagnosed a non-b serotype, non-typeable H.influenzae belonging to lineage H. influenzae 22.1-21. The Oxford Nanopore metagenomic next-generation sequencing approach could be considered for the point-of-care diagnosis of infectious meningitis, by direct identification of pathogenic genomes and their genotypes/serotypes.


2021 ◽  
Vol 21 (2) ◽  
pp. 2241-2255 ◽  
Author(s):  
Tzuu-Hseng S. Li ◽  
Ping-Huan Kuo ◽  
Chuan-Han Cheng ◽  
Chia-Ching Hung ◽  
Po-Chien Luan ◽  
...  

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