Linearisation of high-ratio, wide-range bipolar current mirrors

1993 ◽  
Vol 29 (2) ◽  
pp. 153 ◽  
Author(s):  
C. Olgaard
Pharmaceutics ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 343
Author(s):  
Veronica Folliero ◽  
Carla Zannella ◽  
Annalisa Chianese ◽  
Debora Stelitano ◽  
Annalisa Ambrosino ◽  
...  

Despite advances in medical knowledge, parasitic diseases remain a significant global health burden and their pharmacological treatment is often hampered by drug toxicity. Therefore, drug delivery systems may provide useful advantages when used in combination with conventional therapeutic compounds. Dendrimers are three-dimensional polymeric structures, characterized by a central core, branches and terminal functional groups. These nanostructures are known for their defined structure, great water solubility, biocompatibility and high encapsulation ability against a wide range of molecules. Furthermore, the high ratio between terminal groups and molecular volume render them a hopeful vector for drug delivery. These nanostructures offer several advantages compared to conventional drugs for the treatment of parasitic infection. Dendrimers deliver drugs to target sites with reduced dosage, solving side effects that occur with accepted marketed drugs. In recent years, extensive progress has been made towards the use of dendrimers for therapeutic, prophylactic and diagnostic purposes for the management of parasitic infections. The present review highlights the potential of several dendrimers in the management of parasitic diseases.


Author(s):  
Kalyan Adhikary ◽  
Sayan Das ◽  
Debasish De ◽  
Anup Mondal ◽  
Utpal Gangopadhyay ◽  
...  

Diamond-like Nanocomposites (DLN) is a newly member in amorphous carbon (a:C) family. It consists of two or more interpenetrated atomic scale network structure. The amorphous silicon oxide (a:SiO) is incorporated within diamond-like carbon (DLC) matrix i.e. a:CH and both the network is interpenetrated by Si-C bond. Hence, the internal stress of deposited DLN film decreases remarkably compare to DLC. The diamond like properties has come due to deform tetrahedral carbon with sp3 configuration and high ratio of sp3 to sp2 bond. The DLN has excellent mechanical, electrical, optical and tribological properties. Those the properties of DLN could be varied over a wide range by changing deposition parameters, precursor and even post deposition treatment also. The range of properties are : Resistivity 10-4 to 1014 Ωcm, hardness 10–22 GPa, coefficient of friction 0.03-0.2, wear factor 0.2-0.4 10-7mm3/Nm, transmission Vis-far IR, modulus of elasticity 150-200 GPa, residual stress 200-300 Mpa, Dielectric constant 3-9 and maximum operating temperature 6000C in oxygen environment and 12000C in O2 free air. Generally, the PECVD method is used to synthesis the DLN film. The most common procedures used for investigation of structure and composition of DLN films are Raman spectroscopy, Fourier transformed infrared spectroscopy (FTIR), HRTEM, FESEM and X-ray photo electron spectroscopy (XPS). Interest in the coating technology has been expressed by nearly every industrial segment including automotive, aerospace, chemical processing, marine, energy, personal care, office equipment, electronics, biomedical and tool and die or in a single line from data to beer in all segment of life. In this review paper, characterization of Diamond-like Nanocomposites is discussed and subsequently different application areas are also elaborated.


2019 ◽  
Vol 296 ◽  
pp. 3-8
Author(s):  
David Bujdoš ◽  
Lucia Bulíková

Nowadays, the colouring is used in wide range of architectural concrete. Therefore, determination efficiency of pigments in case of particular combination of input materials is necessary. The research deals with influence of concentration of liquid inorganic pigments on the resulting colour of cement mortars. Two liquid pigments (yellow, red) were used for measurement purposes to verify their optimal ratio to achieve the best colouring of cement specimens. Pigments were mixed in the mortars of two types of cements used for architectural and decorative design. The colour change was determined using Konica Minolta spectrophotometer in colour space CIE Lab (1976). General definition of deviation in the colour space ΔELab was applied for calculating of colour deviation. From the results of the laboratory tests is obvious that significant change of the colour of cement specimens do not show between the concentration of 6% and 9% of the pigment per cement weight yet. Consequently, using of high ratio of pigment than 9% is not profitable neither for purchaser, nor builder. Future research will focus on trials with a more elaborate share of pigment and it will have importance for price optimization in the construction industry.


2020 ◽  
Vol 143 (2) ◽  
Author(s):  
Jaehyeock Chang ◽  
Inbae Chang

Abstract In this study, we propose a high ratio involute gear reducer using the Vernier effect, so-called Vernier drive. Our design consists of a fixed internal gear, a rotating internal gear, and single-profile planetary gears, which are mounted on a carrier and simultaneously mesh with both internal gears. Since the mechanism requires a design beyond the conventional gear meshing principles, a method to modify the tooth profile of the rotating internal gear is introduced and mathematically verified with exact geometric relations. The performance of the Vernier drive is theoretically studied by quasi-static analysis, and the operation is tested with additively manufactured prototypes. The results demonstrate that the Vernier drive is able to cover a wide range of reduction ratios with a simple mechanism.


Author(s):  
Vitalii Vorkov ◽  
Richard Aerens ◽  
Dirk Vandepitte ◽  
Joost R. Duflou

An accurate analytical method is normally the preferred choice in engineering practice since this approach usually does not require additional software and can be applied for different situations. A number of analytical methods have been proposed for the air bending process, however, none of them has the capacity to deal with large radius bending. Large radius bending is characterized by a high ratio of the punch radius to the die opening and it is often applied for high-strength steels because of their limited bendability. This bending mode is used to fulfill the imposed level of maximum strain during the forming process. This contribution develops an analytical solution based on the assumption that the bent plate profile can be represented by two straight lines and a circular segment. Three different hardening laws—linear, Swift, and Aerens—are used for the bending moment calculation. Unit moment measurements are used in order to avoid extrapolation of hardening curves obtained by tensile testing. The model is compared with a wide range of experiments using the coefficient of determination, relative and absolute average errors, in addition to the mean standard error. The analytical prediction based on the circular approximation is found to be an accurate and robust tool for the calculation of the major bending characteristics for large radius air bending of high-strength steels.


2015 ◽  
Vol 1120-1121 ◽  
pp. 1308-1312
Author(s):  
Ming Feng Li ◽  
Zheng Hong Zhu

Electron beam welding technology is a mature special welding technology. The advantage of electron beam welding like these: high power density, high ratio of depth-to-width, high-quality welds. Electron beam welding equipment has been independently developed by tracking and bringing in. Electron beam welding technology has a wide range of applications in the aerospace, automotive, medical and other branches of industry, the field of applications is also expanding with the improved welding equipment. According to the demand of research and market, Electron beam welding technology will move toward the direction of universal, integrated, information-oriented in the future.


1994 ◽  
Vol 72 (12) ◽  
pp. 2169-2171 ◽  
Author(s):  
Michiyori Kobayashi ◽  
Ken-ichi Ishigaki ◽  
Michisuke Kobayashi ◽  
Yoshihiko Igarashi ◽  
Kiyohiro Imai

The Adair constants for Daphnia magna hemoglobin (Hb) oxygen equilibrium curves (OECs) were determined, and the fractional oxygen saturation (Y) was differentiated in terms of partial O2 pressure (p), for Hb-rich (YR) and for Hb-poor (YP) animals. Y′ (dY/dp), which depends on loading and unloading p values of Hb, is used to estimate O2 transport efficiency. The ratio of the Y′ values (Y′R/Y′P) peaked (2.9) at a value close to the p50 of HbR. Using two OECs (YI and YII) for monocomponent human adult Hb A, which have similar O2 affinities to HbR and HbP, respectively, a markedly high ratio of differential coefficients (Y′I/Y′II) was obtained. It is therefore considered that the occurrence of multiple Hb's showing an inverse correlation between Hb concentration and p50, as in D. magna, minimizes the total Hb concentration required for adaptation to a wide range of O2 conditions.


Author(s):  
T. Serrano-Gotarredona ◽  
B. Linares-Barranco ◽  
A.G. Andreou
Keyword(s):  

2007 ◽  
Vol 20 (2) ◽  
pp. 215-221 ◽  
Author(s):  
Slobodan Ðukic

The full-wave wide-band precision rectifier with modified second type current conveyor (MCCII), realized with the operational amplifier and three current mirrors (CM), is presented in this paper. The model of operational amplifier is adapted in such a way that it is possible to use supply-current sensing in supply rails of operational amplifier with SPICE program. Wilson's realization for current mirrors is used for precise current reproduction in a wide range of the amplitude values as well as frequencies.


Author(s):  
P.B. Kurapov ◽  
E.Yu. Bakhtenko

Due to chemical stability, low toxicity, and relative simplicity of synthesis/modification techniques, gold nanoparticles (NP) enjoy a wide range of biomedical applications, including in vitro diagnostics, targeted drug delivery, contrast-enhanced radiation therapy, and photothermal therapy. The high ratio of the gold NP surface area to their volume facilitates design of complex nanoplatforms for various therapeutic and diagnostic purposes. Unique electrical and optical properties of gold NP known as surface plasmon resonance assist medical diagnosis. In this work we look at the basic methods for gold NP synthesis and modification, including the so-called green chemistry, talk about the pharmacological aspects of their application and highlight their potential as diagnostic agents. We believe that due to their unique properties, gold-based nanoplatforms for targeted drug delivery and theranostics have indisputable advantages over other nanoparticles.


Sign in / Sign up

Export Citation Format

Share Document