Bench to Bedside: Research Review in Vocal Fold Extracellular Matrix

2008 ◽  
Vol 18 (3) ◽  
pp. 126-133
Author(s):  
Susan L. Thibeault
Keyword(s):  
Extracellular Matrix ◽  
Lamina Propria ◽  
Basic Science ◽  
Vocal Fold ◽  
Science Research ◽  
Research Review ◽  
The Past ◽  
Basic Science Research ◽  
Quality Of Voice

Abstract The vocal fold lamina propria is crucial for the production of the vocal fold mucosal wave and quality of voice. Basic science research in this area has increased over the past 10 years secondary to our understanding of this importance. The translational aspects of this research are far reaching as we begin to better understand the development, maintenance, and regeneration of this area. This article serves to present a review of the multi faceted work being completed.

An Example of the Role of Basic Science Research to Inform the Treatment of Unilateral Vocal Fold Paralysis

2014 ◽  
Vol 24 (1) ◽  
pp. 37-50 ◽  
Author(s):  
Sid Khosla ◽  
Liran Oren ◽  
Ephraim Gutmark
Keyword(s):  
Flow Separation ◽  
Basic Science ◽  
Vocal Fold ◽  
Science Research ◽  
Vocal Fold Paralysis ◽  
Unilateral Vocal Fold Paralysis ◽  
Production Flow ◽  
Voice Production ◽  
Basic Science Research ◽  
Complementary Approach

An alternative and complementary approach to randomized trials or other clinical research in unilateral vocal fold paralysis is to use basic science research in animal models to answer the following two questions: (1) how and why do asymmetries affect voice production?, and (2) how do various surgical procedures affect these asymmetries? In this article, we will discuss some of our approaches to the first question. All experiments discussed center around the presence and effects of vortices, or areas of rotational motion, between the folds due to a phenomenon known as flow separation. Therefore, the formation and properties of intraglottal flow separation vortices will be briefly discussed. Then, we will describe experiments that look at the effects of the flow separation vortices on three measures of laryngeal physiology important to voice production: flow skewing, acoustic intensity, and glottal efficiency. Finally, we will explore the effects of some asymmetries on the flow separation vortices and discuss implications for the treatment of unilateral vocal fold paralysis. Our work is early and has some clear limitations. Therefore, the goal of this article is not to fully answer any question, but to show an example of the type of information that can be addressed by research in excised canine larynges.

A Perspective On The Impact of COVID-19 Pandemic in Basic Science Research and its Future implications

Coronaviruses ◽  
2020 ◽  
Vol 01 ◽  
Author(s):  
Yam Nath Paudel ◽  
Efthalia Angelopoulou ◽  
Bhupendra Raj Giri ◽  
Christina Piperi ◽  
Iekhsan Othman ◽  
...  
Keyword(s):  
Basic Science ◽  
Large Scale ◽  
Preventive Measure ◽  
Science Research ◽  
Research Institutes ◽  
Basic Science Research ◽  
Long Term Consequences ◽  
Long Term Impact ◽  
The Impact

: COVID-19 has emerged as a devastating pandemic of the century that the current generations have ever experienced. The COVID-19 pandemic has infected more than 12 million people around the globe and 0.5 million people have succumbed to death. Due to the lack of effective vaccines against the COVID-19, several nations throughout the globe has imposed a lock-down as a preventive measure to lower the spread of COVID-19 infection. As a result of lock-down most of the universities and research institutes has witnessed a long pause in basic science research ever. Much has been talked about the long-term impact of COVID-19 in economy, tourism, public health, small and large-scale business of several kind. However, the long-term implication of these research lab shutdown and its impact in the basic science research has not been much focused. Herein, we provide a perspective that portrays a common problem of all the basic science researchers throughout the globe and its long-term consequences.

Setting Up for Success: Strategies to Foster Surgeons’ Pursuit of Basic Science Research

2021 ◽  
Vol 268 ◽  
pp. 71-78
Author(s):  
Devon Livingston-Rosanoff ◽  
Keon Young Park ◽  
Esra Alagoz ◽  
Susan Thibeault ◽  
Angela Gibson
Keyword(s):  
Basic Science ◽  
Science Research ◽  
Success Strategies ◽  
Basic Science Research

scholarly journals Research Productivity and Citation Impact of Indian institutes of Science Education and Research

2021 ◽  
Vol 41 (6) ◽  
pp. 455-462
Author(s):  
Jyotshna Sahoo ◽  
Sudam Charan Sahu ◽  
Basudev Mohanty
Keyword(s):  
Science Education ◽  
Research Productivity ◽  
Basic Science ◽  
Research Output ◽  
Citation Impact ◽  
Science Research ◽  
Publication Patterns ◽  
Research Outcomes ◽  
Basic Science Research ◽  
Research Publications

The paper’s main objective is to investigate the trends of basic science research in India using a combination of qualitative and quantitative approaches. It examines the publication patterns and impact of research productivity of five basic science institutions, i.e., “Indian Institutes of Science Education and Research” (IISER), namely IISER Kolkata, IISER Pune, IISER Mohali, IISER Bhopal, and IISER Thiruvananthapuram. The research output indexed in the SCOPUS bibliographic database of these five established IISERs was obtained from 2015 to 2019. A total number of 7329 research publications were analysed using various scientometric dimensions. This paper makes a concerted effort to present a comprehensive picture of the assessment of research outcomes at the five older IISERs, which are ostensibly India’s most active and prominent basic science research institutions. The findings reveal that these institutions are accountable for important research outcomes, such as a high number of citations, preferences towards open access (OA) publications, a rise in research publication year over year, a strong author network, a high degree of collaboration, and a high impact in terms of other scientometrics indicators. This paper discusses the findings of the research publications on the position of IISERs in basic sciences research and draws some conclusions about their effects.

scholarly journals Basic science research in medicine

2012 ◽  
Vol 8 (3) ◽  
pp. 292-293
Author(s):  
A S Pandey
Keyword(s):  
Basic Science ◽  
Science Research ◽  
Basic Science Research

No abstract availableDOI: http://dx.doi.org/10.3126/kumj.v8i3.6214 Kathmandu Univ Med J 2010;8(3):292-3 

Advances in Basic Science Research

2010 ◽  
pp. 72-77
Author(s):  
Derrick C. Wan ◽  
Matthew D. Kwan ◽  
Eric I-Yun Chang ◽  
Geoffrey C. Gurtner ◽  
Michael T. Longaker
Keyword(s):  
Basic Science ◽  
Science Research ◽  
Basic Science Research

Sustainability in Higher Education through Basic Science Research

2012 ◽  
pp. 56-66
Author(s):  
P. Yogeeswari ◽  
D. Sriram
Keyword(s):  
Higher Education ◽  
Basic Science ◽  
Basic Research ◽  
Science Research ◽  
Medical Sciences ◽  
Industrial Growth ◽  
Non Profit ◽  
Social Sciences And Humanities ◽  
Basic Science Research ◽  
Recent Developments

Basic research in Universities is essential for a sustainable development. Recent developments in higher education have seen the inclusion of curiculum redesigned to serve the concept of developming young minds in the intrepretation, execution, and use of basic science research. The challenge for educators is to “demystify” research and teach in ways that are professionally meaningful as well as intellectually acceptable. The objective of this chapter is to bring in various case studies to prove the essentiality of basic research in higher education with specific concern over pharmaceutical industrial growth plans. Data on R&D in higher education can be broken down by field of science (natural sciences, engineering, medical sciences, agricultural sciences, social sciences, and humanities), by type of costs (current expenditures, capital expenditures), and by source of funds (business enterprise, government, higher education, private non-profit, and funds from abroad). Measures of R&D performance in the higher education sector are often estimated by national authorities, and evaluation methods are periodically revised. It is necessary to review the design and conduct of higher education R&D surveys to improve the comparability of these indicators.

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