scholarly journals Optical biosensors

2016 ◽  
Vol 60 (1) ◽  
pp. 91-100 ◽  
Author(s):  
Pavel Damborský ◽  
Juraj Švitel ◽  
Jaroslav Katrlík
Keyword(s):  
Optical Biosensor ◽  
Optical Biosensors ◽  
Selective Detection ◽  
Reflectometric Interference Spectroscopy ◽  
Spr Imaging ◽  
Wide Range ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Bioanalytical Applications

Optical biosensors represent the most common type of biosensor. Here we provide a brief classification, a description of underlying principles of operation and their bioanalytical applications. The main focus is placed on the most widely used optical biosensors which are surface plasmon resonance (SPR)-based biosensors including SPR imaging and localized SPR. In addition, other optical biosensor systems are described, such as evanescent wave fluorescence and bioluminescent optical fibre biosensors, as well as interferometric, ellipsometric and reflectometric interference spectroscopy and surface-enhanced Raman scattering biosensors. The optical biosensors discussed here allow the sensitive and selective detection of a wide range of analytes including viruses, toxins, drugs, antibodies, tumour biomarkers and tumour cells.

scholarly journals Advanced Nanoporous Anodic Alumina-Based Optical Sensors for Biomedical Applications

2021 ◽  
Vol 3 ◽  
Author(s):  
Silu Feng ◽  
Weiwei Ji
Keyword(s):  
Optical Sensors ◽  
Optical Biosensor ◽  
Nanoporous Structure ◽  
Optical Biosensors ◽  
Formation Mechanisms ◽  
Sensor Applications ◽  
Nanoporous Anodic Alumina ◽  
Reflectometric Interference Spectroscopy ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

Close-packed hexagonal array nanopores are widely used both in research and industry. A self-ordered nanoporous structure makes anodic aluminum oxide (AAO) one of the most popular nanomaterials. This paper describes the main formation mechanisms for AAO, the AAO fabrication process, and optical sensor applications. The paper is focused on four types of AAO-based optical biosensor technology: surface-Enhanced Raman Scattering (SERS), surface Plasmon Resonance (SPR), reflectometric Interference Spectroscopy (RIfS), and photoluminescence Spectroscopy (PL). AAO-based optical biosensors feature very good selectivity, specificity, and reusability.

scholarly journals EM-Wave Biosensors: A Review of RF, Microwave, mm-Wave and Optical Sensing

Sensors ◽  
2019 ◽  
Vol 19 (5) ◽  
pp. 1013 ◽  
Author(s):  
Parikha Mehrotra ◽  
Baibhab Chatterjee ◽  
Shreyas Sen
Keyword(s):  
Wave Interaction ◽  
Optical Biosensors ◽  
Wide Range ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Cancerous Cells ◽  
Permittivity Spectrum ◽  
Reflection Intensity ◽  
Rf Microwave

This article presents a broad review on optical, radio-frequency (RF), microwave (MW), millimeter wave (mmW) and terahertz (THz) biosensors. Biomatter-wave interaction modalities are considered over a wide range of frequencies and applications such as detection of cancer biomarkers, biotin, neurotransmitters and heart rate are presented in detail. By treating biological tissue as a dielectric substance, having a unique dielectric signature, it can be characterized by frequency dependent parameters such as permittivity and conductivity. By observing the unique permittivity spectrum, cancerous cells can be distinguished from healthy ones or by measuring the changes in permittivity, concentration of medically relevant biomolecules such as glucose, neurotransmitters, vitamins and proteins, ailments and abnormalities can be detected. In case of optical biosensors, any change in permittivity is transduced to a change in optical properties such as photoluminescence, interference pattern, reflection intensity and reflection angle through techniques like quantum dots, interferometry, surface enhanced raman scattering or surface plasmon resonance. Conversely, in case of RF, MW, mmW and THz biosensors, capacitive sensing is most commonly employed where changes in permittivity are reflected as changes in capacitance, through components like interdigitated electrodes, resonators and microstrip structures. In this paper, interactions of EM waves with biomatter are considered, with an emphasis on a clear demarcation of various modalities, their underlying principles and applications.

Target induced aggregation of modified Au@Ag nanoparticles for surface enhanced Raman scattering and its ultrasensitive detection of arsenic(iii) in aqueous solution

RSC Advances ◽  
2015 ◽  
Vol 5 (95) ◽  
pp. 77755-77759 ◽  
Author(s):  
Bo Yang ◽  
Xiaochun Chen ◽  
Renyong Liu ◽  
Bianhua Liu ◽  
Changlong Jiang
Keyword(s):  
Aqueous Solution ◽  
Spectroscopic Technique ◽  
Ultrasensitive Detection ◽  
Selective Detection ◽  
Raman Spectroscopic ◽  
Highly Sensitive ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Induced Aggregation

A highly sensitive and selective detection of As(iii) was reported by target induced aggregation of nanoparticles enhanced Raman spectroscopic technique.

Dual platform based sandwich assay surface-enhanced Raman scattering DNA biosensor for the sensitive detection of food adulteration

The Analyst ◽  
2020 ◽  
Vol 145 (4) ◽  
pp. 1414-1426
Author(s):  
Ibrahim Khalil ◽  
Wageeh A. Yehye ◽  
Nurhidayatullaili Muhd Julkapli ◽  
Abu Ali Ibn Sina ◽  
Shahrooz Rahmati ◽  
...  
Keyword(s):  
Raman Scattering ◽  
Short Length ◽  
Dna Biosensor ◽  
Sensitive Detection ◽  
Selective Detection ◽  
Sandwich Assay ◽  
Food Adulteration ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

Raman tag intercalated short-length DNA and dual nanoplatform based SERS DNA biosensor for the ultrasensitive and selective detection of DNA.

scholarly journals Surface-Enhanced Raman Scattering-Based Lateral-Flow Immunoassay

Nanomaterials ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 2228
Author(s):  
Boris Khlebtsov ◽  
Nikolai Khlebtsov
Keyword(s):  
Raman Scattering ◽  
Point Of Care ◽  
Surface Enhanced Raman Scattering ◽  
Environmental Safety ◽  
Lateral Flow ◽  
Wide Range ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Low Sensitivity

Lateral flow immunoassays (LFIAs) have been developed and used in a wide range of applications, in point-of-care disease diagnoses, environmental safety, and food control. However, in its classical version, it has low sensitivity and can only perform semiquantitative detection, based on colorimetric signals. Over the past decade, surface-enhanced Raman scattering (SERS) tags have been developed in order to decrease the detection limit and enable the quantitative analysis of analytes. Of note, these tags needed new readout systems and signal processing algorithms, while the LFIA design remained unchanged. This review highlights SERS strategies of signal enhancement for LFIAs. The types of labels used, the possible gain in sensitivity from their use, methods of reading and processing the signal, and the prospects for use are discussed.

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