Thyroid Function after Medical and Surgical Treatment of Thyrotoxicosis and Non-Toxic Nodular Goitre

1975 ◽  
Vol 48 (1) ◽  
pp. 3P-4P
Author(s):  
N. W. Oakley ◽  
R. D. Simpson ◽  
F. M. Brooke ◽  
D. Burnett ◽  
T. F. Woods ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Thyroid Function ◽  
Nodular Goitre ◽  
Toxic Nodular Goitre

Thyroid antibodies in blood donors: prevalence and clinical significance

1984 ◽  
Vol 105 (3) ◽  
pp. 324-329 ◽  
Author(s):  
T. Bjøro ◽  
P. I. Gaarder ◽  
E. B. Smeland ◽  
L. Kornstad
Keyword(s):  
Thyroid Function ◽  
Blood Donors ◽  
Thyroid Function Test ◽  
Thyroid Antibodies ◽  
Nodular Goitre ◽  
Thyroglobulin Antibodies ◽  
Function Test ◽  
Toxic Nodular Goitre ◽  
Thyroid Microsomal Antibodies

Abstract. In sera from 1643 randomly selected blood donors examined in 1979 thyroglobulin antibodies (TGA) were found in 3.4% and thyroid microsomal antibodies (TMA) in 7.0%. TMA, but not TGA, showed significant sex and age relationships. Eighty-two donors with TMA titres ≥ 1600 and/or TGA titres ≥ 128 were available for a follow-up study in 1982. In 69 of these with TMA there was a significantly increased incidence of pathological thyroid function-test values (T4, T3 and TSH) as compared to age- and sexmatched donors without thyroid antibodies. In this group 9 individuals had overt and three latent hypothyroidism, two individuals were found with symptomless autoimmune thyroiditis and one with a non-toxic nodular goitre. Only 2 of these had been diagnosed before 1982, and none recognized before 1979. In addition, the group contained 9 individuals who had been treated because of hyperthyroidism, all except one before 1979. The likelihood of detecting a previously unrecognized hypothyroidism increased with increasing TMA titre. In contrast, the 24 donors with TGA did not show an increased frequency of pathological thyroid function-test- values in 1982.

Function of Pituitary-Thyroid Axis after Surgical Treatment of Non-Toxic Nodular Goitre

2009 ◽  
Vol 206 (1-6) ◽  
pp. 15-19 ◽  
Author(s):  
M. Blichert-Toft ◽  
J. Egedorf ◽  
C. Christiansen ◽  
C. K. Axelsson
Keyword(s):  
Surgical Treatment ◽  
Nodular Goitre ◽  
Pituitary Thyroid Axis ◽  
Thyroid Axis ◽  
Toxic Nodular Goitre

The efficacy of radioiodine therapy in patients with non-toxic nodular goitre with large cold nodule

2015 ◽  
Author(s):  
Saeid Abdelrazek ◽  
Piotr Szumowski ◽  
Katrzyna Siewko ◽  
Janusz Mysliwiec ◽  
Malgorzata Szelachowska ◽  
...  
Keyword(s):  
Radioiodine Therapy ◽  
Nodular Goitre ◽  
Toxic Nodular Goitre ◽  
Cold Nodule

Enzyme-linked immunosorbent assay of autoantibodies reacting with thyroid plasma membrane antigens in sera of patients with autoimmune thyroid diseases

1986 ◽  
Vol 113 (2) ◽  
pp. 255-260 ◽  
Author(s):  
Andrzej Gardas ◽  
Kathleen L. Rives
Keyword(s):  
Plasma Membrane ◽  
Immunosorbent Assay ◽  
Lupus Erythematosus ◽  
Antithyroid Drug ◽  
Cross Reactivity ◽  
Enzyme Linked Immunosorbent Assay ◽  
Autoimmune Thyroid Diseases ◽  
Nodular Goitre ◽  
Membrane Antigens ◽  
Toxic Nodular Goitre

Abstract. A sensitive and specific enzyme-linked immunosorbent assay (ELISA) for the detection of autoantibodies reacting with thyroid plasma membrane antigens has been established. Autoantibodies reacting with thyroid plasma membrane antigens were detected by the ELISA in 95% of untreated hyperthyroid Graves', 68% of antithyroid drug-treated Graves' up to four months of the therapy, in 62% of Hashimoto's thyroiditis and in 8.9% of toxic nodular goitre. The ELISA was negative in 100% healthy blood donors, 100% non-toxic nodular goitre, in 12 patients with rheumatoid arthritis, 18 patients with scleroderma and 94% of patients with systemic lupus erythematosus. The mean value of autoantibodies titre was higher in untreated hyperthyroid Graves' (1:84 000) and lowest in positive patients with autoimmune disease of non-thyroid origin (1:4000). The cross-reactivity of antimicrosomal antigen antibodies was below 10%; there was no influence of antithyroglobulin antibodies on the ELISA; and most of the autoantibodies react with plasma membrane antigens different from the TSH binding sites.

Development of hypothyroidism during long-term follow-up of patients with toxic nodular goitre after radioiodine therapy

2012 ◽  
Vol 76 (2) ◽  
pp. 297-303 ◽  
Author(s):  
Deniz Kahraman ◽  
Christian Keller ◽  
Christina Schneider ◽  
Wolfgang Eschner ◽  
Ferdinand Sudbrock ◽  
...  
Keyword(s):  
Radioiodine Therapy ◽  
Nodular Goitre ◽  
Long Term Follow Up ◽  
Toxic Nodular Goitre

THYROID CYTOLOGY AND IT'S INTERPRETATION WITH THYROID FUNCTION TEST

2021 ◽  
pp. 80-82
Author(s):  
Dipti Debbarma ◽  
Shipra Singh ◽  
Debarshi Jana ◽  
Chittaranjan Dutta
Keyword(s):  
Thyroid Gland ◽  
Thyroid Function ◽  
Nodular Goiter ◽  
Thyroid Function Test ◽  
Total Serum ◽  
Endocrine Glands ◽  
Nodular Goitre ◽  
Medical College ◽  
Euthyroid State ◽  
Function Test

INTRODUCTION: The Thyroid gland is unique among the endocrine glands. It is the largest of all the endocrine glands and it is supercial in location. It is the only gland which is easily approachable to direct physical, cytological and histopathological examination. The thyroid gland is affected by a variety of pathological lesions that are manifested by various morphologies including developmental, inammatory, hyperplastic and neoplastic pathology which are quiet common in the clinical practice. AIM OFTHE STUDY:In this study, we aimed to assess the cytological ndings of palpable thyroid nodules in conjunction with thyroid hormonal prole of the patient. To study the incidence in relevance to age, sex in various categories of thyroid lesions. MATERIALS & METHODS: Study Design: Institutional based Cross-sectional Study. Duration of study: January 2019 to August 2020. Source of data: Patients presenting to the OPD and admitted in the In-patient ward at Darbhanga Medical College, Bihar. Place of study: Department of Pathology, Darbhanga Medical College and Hospital, Laheriasarai, Bihar. Sample Size: 60 patients of enlarged thyroid gland. RESULTS & OBSERVATIONS: We found that the 53.3% Patients are in euthyroid state. Nodular goitre is the most common nding. In the present study among 60 patients, Nodular goiter accounts for 83.3 % of all cases; 41.7% of them were in euthyroid state, 21.7 % in hypothyroid state , 8.3 % in subclinical hypothyroid and remaining 11.7 % in hyperthyroid state . SUMMARY AND CONCLUSION: FNAC together with thyroid function test (TFT) analysis leads to early and accurate diagnosis of various thyroid diseases and reduces surgical intervention. The study showed that FNAcytologic diagnosis cannot be used to predict thyroid function using total serum T4, T3 and TSH concentrations. Measurement of TSH, free T4, and free T3 would be preferable

Toxic nodular goitre in the cat

1982 ◽  
Vol 23 (1) ◽  
pp. 1-12 ◽  
Author(s):  
MARGARETHE HOENIG ◽  
MICHAEL H. GOLDSCHMIDT ◽  
DUNCAN C. FERGUSON ◽  
KAARON KOCH ◽  
MICHAEL J. EYMONTT
Keyword(s):  
Nodular Goitre ◽  
Toxic Nodular Goitre

Is Paranodular, Grossly Normal Thyroid Tissue from Patients with Non-Toxic Nodular Goitre Really Normal?

1984 ◽  
Vol 16 (09) ◽  
pp. 504-505
Author(s):  
M. Solter ◽  
D. Tišlarić ◽  
M. Dominis ◽  
M. Sekso ◽  
B. Pegan ◽  
...  
Keyword(s):  
Thyroid Tissue ◽  
Normal Thyroid Tissue ◽  
Nodular Goitre ◽  
Normal Thyroid ◽  
Toxic Nodular Goitre
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