A New Method for Assessing States of Acute Acidaemia in Man

1972 ◽  
Vol 42 (4) ◽  
pp. 455-463 ◽  
Author(s):  
J. B. Stoker ◽  
C. T. Kappagoda ◽  
V. A. Grimshaw ◽  
R. J. Linden

1. CO2 titration curves in vivo were determined at various degrees of acute non-respiratory acidaemia in man. 2. The slope of the CO2 titration curve was found to increase as the severity of the acute non-respiratory acidaemia increased. 3. A simple scheme based on the CO2 titration curves in vivo has been proposed for the assessment of acute acidaemia in man.

1975 ◽  
Vol 48 (2) ◽  
pp. 133-138
Author(s):  
J. B. Stoker ◽  
C. T. Kappagoda ◽  
H. M. Snow ◽  
R. J. Linden

1. Carbon dioxide titration curves were determined in vivo in dog and man at various degrees of acute non-respiratory acidaemia and alkalaemia. 2. The slope of the CO2 titration curve (Δlog Pco2/ΔpH) was found to increase with the severity of the acute non-respiratory acidaemia. In states of acute non-respiratory alkalaemia the slope (Δlog Pco2/ΔpH) tended towards unity. 3. A simple scheme based on the CO2 titration curves determined in vivo has been proposed for the assessment of acute acid-base disturbances in man. 4. Carbon dioxide titration curves were also determined in vivo in patients with chronic respiratory and non-respiratory acidaemia and it was found that these curves were not significantly different from those obtained in states of acute acid-base disturbances. It is therefore suggested that the scheme described in this paper is applicable to all acid-base disturbances.


1972 ◽  
Vol 43 (4) ◽  
pp. 553-559 ◽  
Author(s):  
C. T. Kappagoda ◽  
J. B. Stoker ◽  
H. M. Snow ◽  
R. J. Linden

1. Simultaneous CO2 titration curves of arterial and mixed venous blood were determined in both dog and man in vivo. 2. The slopes of the CO2 titration curves of mixed venous blood were significantly less than those of the corresponding arterial curves. 3. The non-respiratory pH values of the CO2 titration curves of mixed venous blood were significantly greater than those of the corresponding arterial curves. 4. The theoretical explanations of these differences have been discussed.


1981 ◽  
Vol 59 (5) ◽  
pp. 500-503
Author(s):  
S. Kaufman ◽  
C. T. Kappagoda

Acute in vivo CO2 titration curves were performed on rats anaesthetized with pentobarbitone. The slope of the in vivo CO2 titration curve in the rat was found to be similar to that previously reported in the dog and in man. Removal of approximately 30% of the haemoglobin of the body did not influence significantly the slope of the in vivo CO2 titration curve in the rat.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Javier Caviedes-Bucheli ◽  
Nestor Rios-Osorio ◽  
Diana Usme ◽  
Cristian Jimenez ◽  
Adriana Pinzon ◽  
...  

Abstract Background The purpose of this study was to evaluate the changes in canal volume after root canal preparation in vivo with 3 different single-file techniques (Reciproc-Blue®, WaveOne-Gold® and XP-EndoShaper®), with a new method using CBCT and 3D reconstruction. Methods In this prospective study, thirty human lower premolars from healthy patients were used, in which extraction was indicated for orthodontic reasons. All the teeth used were caries- and restoration-free with complete root development, without signs of periodontal disease or traumatic occlusion, and with only one straight canal (up to 25º curvature). Teeth were randomly divided into three different groups: Reciproc-Blue, WaveOne-Gold and XP-EndoShaper. CBCT scans before root canal preparation were used to create a 3D reconstruction with RHINOCEROS 5.0 software to assess the initial canal volume, and then compared with 3D reconstructions after canal preparation to measure the increase in canal volume. Student’s t test for paired data were used to determine statistically significant differences between the before and after canal volumes. Anova test was used to determine statistically significant differences in the percentage of canal volume increase between the groups and Tukey's post-hoc test were used to paired comparison. Results Reciproc-Blue showed the higher increase in canal volume, followed by WaveOne-Gold and XP-EndoShaper (p = 0.003). XP-EndoShaper did not show a statistically significant increase in canal volume after root canal preparation (p = 0.06). Conclusion With this model, Reciproc-Blue showed higher increase in root canal volume, followed by WaveOne-Gold, while XP-EndoShaper did not significantly increase root canal volume during preparation.


2014 ◽  
pp. 833-838
Author(s):  
M. Władziński ◽  
K. Wildner ◽  
S. Cygan ◽  
B. Grobelski ◽  
D. Pawełczak ◽  
...  

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