Interactions of the ergosterol biosynthetic pathway with other lipid pathways

2005 ◽  
Vol 33 (5) ◽  
pp. 1178-1181 ◽  
Author(s):  
M. Veen ◽  
C. Lang
Keyword(s):  
Biosynthetic Pathway ◽  
Large Range ◽  
Fats And Oils ◽  
Good Health ◽  
Regulatory Mechanisms ◽  
Disease Treatment ◽  
Treatment And Prevention ◽  
Metabolic Precursors ◽  
Promotion Of Good Health ◽  
Micro Organisms

Micro-organisms have recently received broad attention as sources of novel lipids. An increased understanding of the effects of fats and oils and their composition on the metabolism and on health has shifted the focus towards the use of lipids for disease treatment and prevention and for the promotion of good health. A large range of lipidic products produced by yeast is known today. Ergosterol and its metabolic precursors are major lipidic components of industrial and commercial interest. Having in mind the aim to increase the productivity of ergosterol and its precursor metabolites, both the knowledge of regulatory mechanisms of the biosynthetic pathway and its interactions with other lipid pathways like those of sphingolipids, phospholipids and fatty acids are crucial.

Metabolic precursors in astrophysical ice analogs: implications for meteorites and comets

2015 ◽  
Vol 51 (59) ◽  
pp. 11787-11790 ◽  
Author(s):  
Karen E. Smith ◽  
Perry A. Gerakines ◽  
Michael P. Callahan
Keyword(s):  
Quinolinic Acid ◽  
Biosynthetic Pathway ◽  
Metabolic Precursors

We report the synthesis of nicotinic and quinolinic acid, molecules involved in the NAD biosynthetic pathway, in astrophysical ice analogs.

scholarly journals Ochratoxin A Producing Fungi, Biosynthetic Pathway and Regulatory Mechanisms

Toxins ◽  
2016 ◽  
Vol 8 (3) ◽  
pp. 83 ◽  
Author(s):  
Yan Wang ◽  
Liuqing Wang ◽  
Fei Liu ◽  
Qi Wang ◽  
Jonathan Selvaraj ◽  
...  
Keyword(s):  
Ochratoxin A ◽  
Biosynthetic Pathway ◽  
Regulatory Mechanisms

scholarly journals Western Medicine in a Community in Ghana: A Social Change Review

2019 ◽  
Vol 0 (0) ◽  
Author(s):  
Samuel Adu-Gyamfi ◽  
Razak Mohammed Gyasi ◽  
Dennis Baffour Awuah ◽  
Richard Oware ◽  
Samuel Kwame Ampadu
Keyword(s):  
Rural Communities ◽  
Medical Practice ◽  
Western Medicine ◽  
Skin Diseases ◽  
Local Population ◽  
Good Health ◽  
The People ◽  
Medical Facilities ◽  
History Of ◽  
Promotion Of Good Health

AbstractThis study focuses on Western medical practices in the Atiwa District of Ghana. The people of Atiwa District accessed Western medicinal practice to prevent and cure diseases. Before the advent of Western medical practice in the Atiwa District, people were unable to access Western medicine due to the challenges with travelling or trekking from rural communities to the towns where they would find limited Western oriented health centres/hospitals. Although there were challenges, the local population continued to highly embrace practitioners and also accessed the basic Western oriented medical facilities. Western medical strategies were used to combat skin diseases, stomach aches, and malaria that was prevalent in the Atiwa District. The other diseases which afflicted the people and which required urgent attention included cerebrospinal meningitis (CSM), tuberculosis and HIV/AIDS among others. Findings from the study revealed that the introduction and success of western medical practice in the Atiwa District could not have been possible without a positive reception from the indigenous people. Importantly, this study has projected the relevance of public health in the history of the people of Atiwa and the significant roles played by governments to ensure the promotion of good health at the District.

scholarly journals EFFECTS OF TAKRADHARA ON PSYCHO-SOMATIC DISORDERS: A REVIEW

2020 ◽  
Vol 11 (5) ◽  
pp. 135-137
Author(s):  
Raghunath Das ◽  
Devkumar Das ◽  
Dipanjan Jana
Keyword(s):  
Good Health ◽  
The Body ◽  
Healthy Life ◽  
Life Process ◽  
Specific Manner ◽  
Lack Of Sleep ◽  
Somatic Disorders ◽  
Effective Role ◽  
Promotion Of Good Health ◽  
Modern Era

In modern era, Ayurveda is a ‘science of life’ which deals with the maintenance, preservation and promotion of good health and cures the diseases in healthy life that established in various Ayurvedic classics. In Ayurveda system of medicine, Panchakarma has a very effective role for detoxification to the body in healthy life process. It includes with five major procedures which prevents various diseased conditions. Takradhara is one among the Panchakarma procedure included under the Murdhani taila (a process of anointing the head with oil) in ancient Ayurvedic science. It is a unique Panchakarma measure in which medicated milk poured over the forehead in a specific manner. Takradhara is very much effective in such cases of various psycho-somatic conditions which occur due to vitiation of Manasvaha srotas like as lack of sleep, migraine, anxiety, stress, headache etc that are scientifically proved based on many research works.

Bioconversion of Vegetable, Animal, and Industrial Wastes by Means of Fungi Mycelia in an Artificial Rumen

1986 ◽  
Vol 8 (1) ◽  
pp. 1-6
Author(s):  
Atanas Torev
Keyword(s):  
Large Range ◽  
Industrial Wastes ◽  
Submerged Cultivation ◽  
World Collection ◽  
The World ◽  
Micro Organisms

In nature there are several thousand different higher fungi species, but not all of them have mycelia whose characteristics are in optimum combinations. Many of these fungi cannot be subjected to submerged cultivation, do not assimilate a large range of substrates, synthesize only a small amount of protein, and have an unsatisfactory degree of protein assimilation and other limitations. The V. Kolarov Higher Institute of Agriculture in Plovdiv, Bulgaria, has isolated strains of higher fungi mycelia that combine the most desirable biological, technological, and nutritive characteristics. A strain called PS-64 is especially promising. It was isolated in 1964, patented, and registered in the world collection of micro-organisms. PS-64 is available for license.

scholarly journals Effect of streptomycin on lipid composition with particular reference to cyclic depsipeptide biosynthesis in Serratia marcescens and other micro-organisms

1970 ◽  
Vol 119 (5) ◽  
pp. 861-869 ◽  
Author(s):  
Margaret A. C. Bermingham ◽  
B. S. Deol ◽  
J. L. Still
Keyword(s):  
Serratia Marcescens ◽  
Total Lipid ◽  
Lipid Composition ◽  
Biosynthetic Pathway ◽  
Nocardia Asteroides ◽  
Cyclic Depsipeptide ◽  
Low Concentrations ◽  
Site Of Action ◽  
Rhodopseudomonas Spheroides ◽  
Micro Organisms

The addition of low concentrations of streptomycin (5–10μg/ml of medium) to Serratia marcescens caused significant alterations in the lipid composition of this organism, but neither growth nor pigmentation was affected. The acetone-soluble cyclic depsipeptides, which comprise on average 15% of the total lipid, were decreased almost to zero and the total lipid phosphorus was more than doubled in the presence of streptomycin. Most of the phospholipid increase was due to an increase in phosphatidylethanolamine. Cyclic depsipeptides were not leached from the cell in the presence of streptomycin, indicating a definite inhibition of the biosynthetic pathway. The effect of streptomycin on the reported peptidolipids of Rhodopseudomonas spheroides, Halobacterium halobium, Nocardia asteroides and Pseudomonas tabaci was investigated. In the case of the only strictly comparable cellular cyclic depsipeptide (that of N. asteroides) the biosynthesis was strongly inhibited by streptomycin, but cell weight was maintained or even slightly increased. A possible mode and site of action of low concentrations of streptomycin on bacterial lipids is discussed.

Precision medicine: opportunities, possibilities, and challenges for patients and providers

2016 ◽  
Vol 23 (4) ◽  
pp. 787-790 ◽  
Author(s):  
Samantha A Adams ◽  
Carolyn Petersen
Keyword(s):  
Precision Medicine ◽  
Large Scale ◽  
Healthcare Professionals ◽  
Social Issues ◽  
Point Of Care ◽  
Individual Variability ◽  
Disease Treatment ◽  
Social Challenges ◽  
Treatment And Prevention ◽  
New Research

Abstract Precision medicine approaches disease treatment and prevention by taking patients’ individual variability in genes, environment, and lifestyle into account. Although the ideas underlying precision medicine are not new, opportunities for its more widespread use in practice have been enhanced by the development of large-scale databases, new methods for categorizing and representing patients, and computational tools for analyzing large datasets. New research methods may create uncertainty for both healthcare professionals and patients. In such situations, frameworks that address ethical, legal, and social challenges can be instrumental for facilitating trust between patients and providers, but must protect patients while not stifling progress or overburdening healthcare professionals. In this perspective, we outline several ethical, legal, and social issues related to the Precision Medicine Initiative’s proposed changes to current institutions, values, and frameworks. This piece is not an exhaustive overview, but is intended to highlight areas meriting further study and action, so that precision medicine’s goal of facilitating systematic learning and research at the point of care does not overshadow healthcare’s goal of providing care to patients.

scholarly journals Views of Zulus and Southern Sothos on immunisation

Curationis ◽  
1984 ◽  
Vol 7 (2) ◽  
Author(s):  
A.J. Lubbe
Keyword(s):  
Health Care ◽  
Health Status ◽  
Infectious Diseases ◽  
Community Health ◽  
Good Health ◽  
Community Health Care ◽  
Promotion Of Good Health ◽  
Overall Health Status

The promotion of good health and the prevention of disease are two of the aims of community health care that can, to a large extent be realised by means of immunisation. Immunisation does not only make it possible to control the spread of a number of infectious diseases, but also enhances the overall health status of a community.

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