Molecular characterization of the AMP-activated protein kinase and its role in cellular metabolism

1997 ◽  
Vol 25 (4) ◽  
pp. 1224-1228 ◽  
Author(s):  
D. Carling ◽  
A. Woods ◽  
C. Thornton ◽  
P. C. F. Cheung ◽  
F. C. Smith ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Molecular Characterization ◽  
Cellular Metabolism ◽  
Amp Activated Protein Kinase

A molecular approach to the concerted action of kinases involved in energy homoeostasis

2003 ◽  
Vol 31 (1) ◽  
pp. 169-174 ◽  
Author(s):  
D. Neumann ◽  
U. Schlattner ◽  
T. Wallimann
Keyword(s):  
Protein Kinase ◽  
Adenylate Kinase ◽  
Energy Production ◽  
Molecular Level ◽  
Concerted Action ◽  
A Cell ◽  
Response To Stress ◽  
Downstream Processes ◽  
Amp Activated Protein Kinase

One of the most important duties of a cell is energy homoeostasis. Several kinases, including AMP-activated protein kinase (AMPK), creatine kinase and adenylate kinase, are involved in the immediate response to stress, resulting in energy depletion. Here, we present our view of events preceding the downstream processes mediated by AMPK and leading to reduced energy expenditure and increased energy production. Unfortunately, AMPK is very poorly defined at the molecular level. Thus a procedure for production of AMPK in milligram amounts is presented which will greatly facilitate the functional and structural characterization of this protein kinase.

scholarly journals Molecular characterization of protein kinase C delta (PKCδ)-Smac interactions

2016 ◽  
Vol 17 (1) ◽  
Author(s):  
Christian Holmgren ◽  
Louise Cornmark ◽  
Gry Kalstad Lønne ◽  
Katarzyna Chmielarska Masoumi ◽  
Christer Larsson
Keyword(s):  
Protein Kinase C ◽  
Protein Kinase ◽  
Molecular Characterization ◽  
Protein Kinase C Delta ◽  
Kinase C
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