EFFECT OF ELECTRICAL STIMULATION OF THE SCIATIC NERVE IN ANAESTHETIZED RATS ON CONTENT OF CGRP IN RAT SKELETAL MUSCLE

1991 ◽  
Vol 19 (2) ◽  
pp. 134S-134S
Author(s):  
BRENDAN LEIGHTON ◽  
LEONARD ARNOLDA
Keyword(s):  
Skeletal Muscle ◽  
Electrical Stimulation ◽  
Sciatic Nerve ◽  
Rat Skeletal Muscle ◽  
Anaesthetized Rats ◽  
Stimulation Of

Inflammatory cells in rat skeletal muscle are elevated after electrically stimulated contractions

2003 ◽  
Vol 94 (3) ◽  
pp. 876-882 ◽  
Author(s):  
Thomas J. McLoughlin ◽  
Eleni Mylona ◽  
Troy A. Hornberger ◽  
Karyn A. Esser ◽  
Francis X. Pizza
Keyword(s):  
Skeletal Muscle ◽  
Electrical Stimulation ◽  
Sciatic Nerve ◽  
High Frequency ◽  
Tibialis Anterior ◽  
Inflammatory Cells ◽  
Muscle Contractions ◽  
Rat Skeletal Muscle ◽  
Concentric Contractions ◽  
Time Point

We determined the effect of muscle contractions resulting from high-frequency electrical stimulation (HFES) on inflammatory cells in rat tibialis anterior (TA), plantaris (Pln), and soleus (Sol) muscles at 6, 24, and 72 h post-HFES. A minimum of four and a maximum of seven rats were analyzed at each time point. HFES, applied to the sciatic nerve, caused the Sol and Pln to contract concentrically and the TA to contract eccentrically. Neutrophils were higher ( P < 0.05) at 6 and 24 h after HFES in the Sol, Pln, and TA muscles relative to control muscles. ED1+ macrophages in the Pln were elevated at 6 and 24 h after HFES and were also elevated in the Sol and TA after HFES relative to controls. ED2+ macrophages in the Sol and TA were elevated at 24 and 72 h after HFES, respectively, and were also elevated in the Pln after HFES relative to controls. In contrast to the TA muscles, the Pln and Sol muscles showed no gross histological abnormalities. Collectively, these data indicate that both eccentric and concentric contractions can increase inflammatory cells in muscle, regardless of whether overt histological signs of injury are apparent.

Electrical Stimulation of Denervated Rat Skeletal Muscle Ameliorates Bone Fragility and Muscle Loss in Early-Stage Disuse Musculoskeletal Atrophy

2017 ◽  
Vol 100 (4) ◽  
pp. 420-430 ◽  
Author(s):  
Hiroyuki Tamaki ◽  
Kengo Yotani ◽  
Futoshi Ogita ◽  
Keishi Hayao ◽  
Kouki Nakagawa ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Electrical Stimulation ◽  
Early Stage ◽  
Bone Fragility ◽  
Muscle Loss ◽  
Rat Skeletal Muscle ◽  
Stimulation Of

ATP concentrations and muscle tension increase linearly with muscle contraction

2003 ◽  
Vol 95 (2) ◽  
pp. 577-583 ◽  
Author(s):  
Jianhua Li ◽  
Nicholas C. King ◽  
Lawrence I. Sinoway
Keyword(s):  
Skeletal Muscle ◽  
Electrical Stimulation ◽  
Muscle Contraction ◽  
Motor Nerve ◽  
Muscle Tension ◽  
Nerve Fibers ◽  
Ventral Root ◽  
Ventral Roots ◽  
Root Stimulation ◽  
Stimulation Of

Previous studies have suggested that activation of ATP-sensitive P2X receptors in skeletal muscle play a role in mediating the exercise pressor reflex (Li J and Sinoway LI. Am J Physiol Heart Circ Physiol 283: H2636–H2643, 2002). To determine the role ATP plays in this reflex, it is necessary to examine whether muscle interstitial ATP (ATPi) concentrations rise with muscle contraction. Accordingly, in this study, muscle contraction was evoked by electrical stimulation of the L7 and S1 ventral roots of the spinal cord in 12 decerebrate cats. Muscle ATPi was collected from microdialysis probes inserted in the muscle. ATP concentrations were determined by the HPLC method. Electrical stimulation of the ventral roots at 3 and 5 Hz increased mean arterial pressure by 13 ± 2 and 16 ± 3 mmHg ( P < 0.05), respectively, and it increased ATP concentration in contracting muscle by 150% ( P < 0.05) and 200% ( P < 0.05), respectively. ATP measured in the opposite control limb did not rise with ventral root stimulation. Section of the L7 and S1 dorsal roots did not affect the ATPi seen with 5-Hz ventral root stimulation. Finally, ventral roots stimulation sufficient to drive motor nerve fibers did not increase ATP in previously paralyzed cats. Thus ATPi is not largely released from sympathetic or motor nerves and does not require an intact afferent reflex pathway. We conclude that ATPi is due to the release of ATP from contracting skeletal muscle cells.

Neurons of the A5 region are required for the tachycardia evoked by electrical stimulation of the hypothalamic defence area in anaesthetized rats

2013 ◽  
Vol 98 (8) ◽  
pp. 1279-1294 ◽  
Author(s):  
M. V. López-González ◽  
A. Díaz-Casares ◽  
C. A. Peinado-Aragonés ◽  
J. P. Lara ◽  
M. A. Barbancho ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Anaesthetized Rats ◽  
A5 Region ◽  
Stimulation Of

scholarly journals The effect of repeated bouts of electrical stimulation‐induced muscle contractions on proteolytic signaling in rat skeletal muscle

2021 ◽  
Vol 9 (9) ◽  
Author(s):  
Takaya Kotani ◽  
Junya Takegaki ◽  
Yuki Tamura ◽  
Karina Kouzaki ◽  
Koichi Nakazato ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Electrical Stimulation ◽  
Muscle Contractions ◽  
Rat Skeletal Muscle

Insulin increases thermogenesis in rat skeletal muscle following exercise

1985 ◽  
Vol 248 (1) ◽  
pp. E148-E151
Author(s):  
T. W. Balon ◽  
A. Zorzano ◽  
M. N. Goodman ◽  
N. B. Ruderman
Keyword(s):  
Skeletal Muscle ◽  
Insulin Secretion ◽  
Glycogen Synthesis ◽  
O2 Consumption ◽  
Rat Skeletal Muscle ◽  
Additional Energy ◽  
Rat Muscle ◽  
Prior Exercise ◽  
Increase Insulin Secretion ◽  
Stimulation Of

Insulin increased O2 consumption in isolated perfused rat muscle for upward of 2 h after a treadmill run. Insulin did not increase O2 consumption in nonexercised rats, nor did prior exercise increase O2 consumption in the absence of added insulin. The stimulation of glycogen synthesis by insulin was also enhanced in muscle of previously exercised rats. The additional energy required for this was not sufficient to account for the increase in O2 consumption, however. The results indicate that insulin increases thermogenesis in skeletal muscle after exercise. They also raise the possibility that in intact organisms the thermogenic effect of foods that increase insulin secretion could be increased by prior exercise.

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