Polyamine oxidase activity in a human colonic carcinoma cell line

1990 ◽  
Vol 18 (6) ◽  
pp. 1225-1225 ◽  
Author(s):  
KHAWOLA A. FLAYEH ◽  
HEATHER M. WALLACE
1981 ◽  
Vol 193 (1) ◽  
pp. 109-113 ◽  
Author(s):  
P M Kimball ◽  
M G Brattain ◽  
W E White

A sub-line with increased metastatic ability was previously isolated from an established human colonic carcinoma cell line [Kimball & Brattain (1980) Cancer Res. 40, 1574-1579]. The separation and characterization of the isoenzymes of N-acetyl-beta-D-hexosaminidase from each cell line are reported. The parental cell line contained A and B isoenzymes. The sub-line lacked the A-isoenzyme activity and contained an atypical B isoenzyme that was thermolabile, susceptible to alkylation and of lower molecular weight.


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