360-MHz 1H-NMR AND 50-MHz 13C-NMR STUDIES OF OLIGOSACCHARIDES FROM GLYCOSAMINOGLYCANS

1981 ◽  
Vol 9 (2) ◽  
pp. 283P-283P ◽  
Author(s):  
H. van Halbeek ◽  
G. A. Veldink ◽  
L. Dorland ◽  
J. F. G. Vliegenthart ◽  
A. Kimura ◽  
...  
Keyword(s):  
1H Nmr ◽  
13C Nmr ◽  
Nmr Studies

1H NMR and 13C NMR Studies of Oil from Pyrolysis of Indonesian Oil Sands

2016 ◽  
Vol 30 (3) ◽  
pp. 2478-2491 ◽  
Author(s):  
Wang Qing ◽  
Jia Chunxia ◽  
Ge Jianxin ◽  
Guo Wenxue
Keyword(s):  
1H Nmr ◽  
13C Nmr ◽  
Oil Sands ◽  
Nmr Studies

EXTRACTION, ISOLATION AND SYNTHESIS OF DERIVATIVES OF URSOLIC ACID

INDIAN DRUGS ◽  
2012 ◽  
Vol 49 (01) ◽  
pp. 33-37
Author(s):  
S. B. Babar ◽  
◽  
K. S. Laddha
Keyword(s):  
Petroleum Ether ◽  
Ursolic Acid ◽  
1H Nmr ◽  
13C Nmr ◽  
Methanol Extract ◽  
Nmr Studies ◽  
Simple Method ◽  
Synthetic Derivatives ◽  
Derivatives Of

Study was undertaken with an objective to develop a simple method for isolation of ursolic acid from Nerium indicum Mill leaves and to prepare synthetic derivatives of ursolic acid. The leaves were defatted with petroleum ether and then extracted with methanol. Methanol extract was basified and subsequently acidified, followed by charcoal treatment to isolate ursolic acid. Synthetic derivatives were prepared from isolated ursolic acid by substitution at C-3 position. The structure of ursolic acid and its derivatives were confirmed by IR, MS, 1H NMR, 13C NMR studies.

Characterization of oligosaccharides from the chondroitin/dermatan sulfates. 1H-NMR and 13C-NMR studies of reduced trisaccharides and hexasaccharides

FEBS Journal ◽  
2005 ◽  
Vol 272 (24) ◽  
pp. 6276-6286 ◽  
Author(s):  
Thomas N. Huckerby ◽  
Ian A. Nieduszynski ◽  
Marcos Giannopoulos ◽  
Stephen D. Weeks ◽  
Ian H. Sadler ◽  
...  
Keyword(s):  
1H Nmr ◽  
13C Nmr ◽  
Nmr Studies

scholarly journals 1D AND 2D NMR STUDIES OF BENZYL O–VANILLIN

2010 ◽  
Vol 8 (3) ◽  
pp. 411-417 ◽  
Author(s):  
Mohammed Hadi Al–Douh ◽  
Shafida Abd Hamid ◽  
Hasnah Osman
Keyword(s):  
1H Nmr ◽  
13C Nmr ◽  
Benzyl Bromide ◽  
2D Nmr ◽  
Coupling Constants ◽  
Nmr Studies

The reaction of o-vanillin A with benzyl bromide B2 in acetone as the solvent and K2CO3 as a base in the presence of tetra-n-butylammonium iodide (TBAI) as catalyst formed benzyl o-vanillin, C. The complete assignments of C using PROTON, APT, DEPT-135, COSY, NOESY, HMQC and HMBC NMR in both CDCl3 and acetone-d6 are discussed, and the coupling constants J are reported in Hertz (Hz).     Keywords: 1H NMR; 13C NMR; 2D NMR; Benzyl o-Vanillin

scholarly journals Microwave-Assisted Regioselective Synthesis and 2D-NMR Studies of New 1,2,3-Triazole Compounds Derived from Acridone

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Mohammed Aarjane ◽  
Siham Slassi ◽  
Bouchra Tazi ◽  
Amina Amine
Keyword(s):  
1H Nmr ◽  
13C Nmr ◽  
Cycloaddition Reaction ◽  
Reaction Times ◽  
2D Nmr ◽  
Dipolar Cycloaddition ◽  
Microwave Assisted Synthesis ◽  
Nmr Studies ◽  
Microwave Assisted ◽  
Acridone Derivatives

A simple and mild protocol towards the synthesis of new 1,2,3-triazole compounds derived from acridone has been developed via regiospecific 1,3-dipolar cycloaddition reaction between 10-(prop-2-yn-1-yl)acridone derivatives and aromatic azides using CuI as a catalyst. The cycloaddition reaction has been performed using conventional as well as microwave-assisted methods. Microwave-assisted synthesis caused a significant reduction in the reaction times and improvement in the yields of all the synthesized compounds compared with the conventional method. The structure of the 1,4-disubstituted 1,2,3-triazoles has been elucidated by IR, HRMS, 1H-NMR, 13C-NMR, and 2D NMR (1H-13C HMBC, 1H-1H COSY, and 1H-1H NOESY) spectroscopies.

13C- and 1H-NMR studies of oxyanion and tetrahedral intermediate stabilization by the serine proteinases: optimizing inhibitor warhead specificity and potency by studying the inhibition of the serine proteinases by peptide-derived chloromethane and glyoxal inhibitors

2007 ◽  
Vol 35 (3) ◽  
pp. 566-570 ◽  
Author(s):  
J.P.G. Malthouse
Keyword(s):  
1H Nmr ◽  
13C Nmr ◽  
Proteinase Inhibitors ◽  
Serine Proteinase ◽  
Serine Proteinases ◽  
Nmr Studies ◽  
Oxyanion Hole ◽  
Optimal Position ◽  
Reversible Inhibitors ◽  
Tetrahedral Intermediate

Catalysis by the serine proteinases proceeds via a tetrahedral intermediate whose oxyanion is stabilized by hydrogen-bonding in the oxyanion hole. There have been extensive 13C-NMR studies of oxyanion and tetrahedral intermediate stabilization in trypsin, subtilisin and chymotrypsin using substrate-derived chloromethane inhibitors. One of the limitations of these inhibitors is that they irreversibly alkylate the active-site histidine residue which results in the oxyanion not being in the optimal position in the oxyanion hole. Substrate-derived glyoxal inhibitors are reversible inhibitors which, if they form tetrahedral adducts in the same way as substrates form tetrahedral intermediates, will overcome this limitation. Therefore we have synthesized 13C-enriched substrate-derived glyoxal inhibitors which have allowed us to use 13C-NMR and 1H-NMR to determine how they interact with proteinases. It is hoped that these studies will help in the design of specific and highly potent warheads for serine proteinase inhibitors.

scholarly journals 1D AND 2D NMR STUDIES OF 2–(2–(BENZYLOXY)–3–METHOXYPHENYL)–1H–BENZIMIDAZOLE

2010 ◽  
Vol 7 (2) ◽  
pp. 190-196
Author(s):  
Mohammed Hadi Al–Douh ◽  
Shafida Abd Hamid ◽  
Hasnah Osman
Keyword(s):  
1H Nmr ◽  
13C Nmr ◽  
2D Nmr ◽  
Coupling Constants ◽  
Nmr Studies ◽  
Phenylene Diamine

The reaction of Benzyl o-vanillin 1 and o-phenylene diamine 2 in dichloromethane produced new benzimidazole, 3. The complete assignments of 3 were made using 1D and 2D NMR including COSY, HMQC and HMBC NMR in CDCl3 and acetone-d6. The coupling constants J are reported in Hertz, and the differences in the peak splittings using both solvents are discussed.   Keywords: 1H NMR; 13C NMR; 2D NMR; Benzimidazole

Synthesis and Biological Evaluation of Various New Substituted 1,3,4-oxadiazole-2-thiols

2008 ◽  
Vol 59 (4) ◽  
Author(s):  
Gabriela Laura Almajan ◽  
Stefania Felicia Barbuceanu ◽  
Ioana Saramet ◽  
Mihaela Dinu ◽  
Cristian Vasile Doicin ◽  
...  
Keyword(s):  
Biological Activity ◽  
Plant Growth ◽  
1H Nmr ◽  
Elemental Analysis ◽  
13C Nmr ◽  
Biological Evaluation ◽  
Ethyl Chloroacetate ◽  
Low Concentrations ◽  
Synthesis And Biological Evaluation

5-[4-(4X-phenylsulfonyl)phenyl]-1,3,4-oxadiazole-2-thiols, X=H, Cl, Br, reacted with ethyl chloroacetate to give S-alkylated compounds. Aminomethylation of the thione form of oxadiazoles yielded N(3)-derivatives. All the products have been characterized by elemental analysis, IR, 1H-NMR and 13C-NMR. The plant-growth regulating effects of the title compounds were examined. From the biological activity results, we found that most compounds showed weak stimulatory activities at low concentrations.

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