Occupancy of Muscarinic Acetylcholine Receptors Stimulates a Guanylate Cyclase in Neuroblastoma Cells

1977 ◽  
Vol 5 (1) ◽  
pp. 189-191 ◽  
Author(s):  
PHILIP G. STRANGE ◽  
NIGEL J. M. BIRDSALL ◽  
ARNOLD S. V. BURGEN
Keyword(s):  
Guanylate Cyclase ◽  
Acetylcholine Receptors ◽  
Neuroblastoma Cells ◽  
Muscarinic Acetylcholine Receptors ◽  
Muscarinic Acetylcholine

scholarly journals Ligand-binding propeties of the muscarinic acetylcholine receptor in mouse neuroblastoma cells

1978 ◽  
Vol 172 (3) ◽  
pp. 495-501 ◽  
Author(s):  
P G Strange ◽  
N J M Birdsall ◽  
A S V Burgen
Keyword(s):  
Acetylcholine Receptors ◽  
Neuroblastoma Cells ◽  
Muscarinic Acetylcholine Receptor ◽  
Muscarinic Acetylcholine Receptors ◽  
Mass Action ◽  
Similar Data ◽  
Muscarinic Acetylcholine ◽  
Mouse Neuroblastoma ◽  
Good Agreement ◽  
Quinuclidinyl Benzilate

1. Muscarinic acetylcholine receptors in a plasma-membrane fraction derived from mouse neuroblastoma clone NIE-115 bind [3-3H]quinuclidinyl benzilate according to the Law of Mass Action (Kdissociation 40 pM, h0.96). 2. Antagonist and agonist binding to the receptor was studied by displacement of [3-3H]quinuclidinyl benzilate with non-radioactive ligands. The data show good agreement with similar data obtained on rat brain and ideal smooth muscle [Birdsall & Hulme (1976) J. Neurochem. 27, 7-16] indicating that the receptor is very similar in these three tissues.

scholarly journals Intracellular distribution of functional M1-muscarinic acetylcholine receptors in N1E-115 neuroblastoma cells

2011 ◽  
Vol 118 (6) ◽  
pp. 958-967 ◽  
Author(s):  
Junsuke Uwada ◽  
Abu Syed Md Anisuzzaman ◽  
Atsushi Nishimune ◽  
Hatsumi Yoshiki ◽  
Ikunobu Muramatsu
Keyword(s):  
Acetylcholine Receptors ◽  
Neuroblastoma Cells ◽  
Intracellular Distribution ◽  
Muscarinic Acetylcholine Receptors ◽  
Muscarinic Acetylcholine ◽  
M1 Muscarinic
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