Lack of function of histamine H1 and muscarinic acetylcholine receptors of mouse neuroblastoma cells grown in serum-free medium

In Vitro ◽  
1982 ◽  
Vol 18 (3) ◽  
pp. 175-178 ◽  
Author(s):  
J. Carlson ◽  
A. Smith ◽  
E. Richelson
1978 ◽  
Vol 172 (3) ◽  
pp. 495-501 ◽  
Author(s):  
P G Strange ◽  
N J M Birdsall ◽  
A S V Burgen

1. Muscarinic acetylcholine receptors in a plasma-membrane fraction derived from mouse neuroblastoma clone NIE-115 bind [3-3H]quinuclidinyl benzilate according to the Law of Mass Action (Kdissociation 40 pM, h0.96). 2. Antagonist and agonist binding to the receptor was studied by displacement of [3-3H]quinuclidinyl benzilate with non-radioactive ligands. The data show good agreement with similar data obtained on rat brain and ideal smooth muscle [Birdsall & Hulme (1976) J. Neurochem. 27, 7-16] indicating that the receptor is very similar in these three tissues.


2011 ◽  
Vol 118 (6) ◽  
pp. 958-967 ◽  
Author(s):  
Junsuke Uwada ◽  
Abu Syed Md Anisuzzaman ◽  
Atsushi Nishimune ◽  
Hatsumi Yoshiki ◽  
Ikunobu Muramatsu

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