The Subcellular Distribution of Aurothiomalate in Rat Liver in vivo

1974 ◽  
Vol 2 (5) ◽  
pp. 896-899 ◽  
Author(s):  
KATHERINE J. LAWSON ◽  
CHRISTOPHER J. DANPURE ◽  
DAVID A. FYFE ◽  
RICHARD W. E. WATTS
Keyword(s):  
Rat Liver ◽  
Subcellular Distribution

scholarly journals Subcellular distribution of glycosylphosphatidylinositol-specific phospholipase D in rat liver

1996 ◽  
Vol 320 (1) ◽  
pp. 315-319 ◽  
Author(s):  
Thomas HARI ◽  
Hans KUNZE ◽  
Ernst BOHN ◽  
Urs BRODBECK ◽  
Peter BÜTIKOFER
Keyword(s):  
Rat Liver ◽  
Phospholipase D ◽  
Subcellular Distribution ◽  
Lysosomal Enzymes ◽  
Body Fluids ◽  
Intracellular Distribution ◽  
Lysosomal Fraction ◽  
Mammalian Tissues

Glycosylphosphatidylinositol (GPI)-hydrolysing enzymes have been described in many mammalian tissues and body fluids; however, their site(s) of action and in vivo functions have remained unclear. In order to identify a possible intracellular site of GPI hydrolysis, we studied the subcellular distribution of GPI-hydrolysing activity in rat liver. We found that purified fractions from rat liver hydrolysed the GPI moieties of two GPI-anchored proteins with the specificity of a phospholipase D. This GPI-specific phospholipase D (GPI-PLD) activity was found to be highly enriched in a lysosomal fraction and showed a similar intracellular distribution to that of typical lysosomal enzymes. Our results indicate that lysosomes may represent a possible intracellular site of GPI-PLD action.

Effect of X-irradiation on gene expression of rat liver chemokines: in vivo and in vitro studies

2008 ◽  
Vol 46 (01) ◽  
Author(s):  
F Moriconi ◽  
H Christiansen ◽  
H Christiansen ◽  
N Sheikh ◽  
J Dudas ◽  
...  
Keyword(s):  
Gene Expression ◽  
Rat Liver ◽  
In Vitro Studies ◽  
X Irradiation

Chronic, in vivo, PPARα activation prevents lipid overload in rat liver induced by high fat feeding

2009 ◽  
Vol 54 (1) ◽  
Author(s):  
M Wierzbicki ◽  
A Chabowski ◽  
M Żendzian-Piotrowska ◽  
E Harasim ◽  
J Górski
Keyword(s):  
Rat Liver ◽  
High Fat ◽  
Fat Feeding

scholarly journals Internalization and Activation of the Rat Liver Insulin Receptor Kinase in vivo

1989 ◽  
Vol 264 (22) ◽  
pp. 12931-12940 ◽  
Author(s):  
M N Khan ◽  
G Baquiran ◽  
C Brule ◽  
J Burgess ◽  
B Foster ◽  
...  
Keyword(s):  
Insulin Receptor ◽  
Rat Liver ◽  
Receptor Kinase ◽  
Insulin Receptor Kinase

scholarly journals The Metabolism of Intraportally Injected Fructose in Rat Liver in Vivo

1962 ◽  
Vol 237 (12) ◽  
pp. 3582-3587
Author(s):  
John A. Muntz ◽  
Michael Vanko
Keyword(s):  
Rat Liver
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