scholarly journals The effects of recombinant tumour necrosis factor (cachectin) on metabolism in isolated rat adipocyte, hepatocyte and muscle preparations

1987 ◽  
Vol 247 (3) ◽  
pp. 789-792 ◽  
Author(s):  
A M Rofe ◽  
R A J Conyers ◽  
R Bais ◽  
J R Gamble ◽  
M A Vadas
Keyword(s):  
Tumour Necrosis Factor ◽  
Tumour Necrosis ◽  
Lactate Production ◽  
Rat Hepatocytes ◽  
Short Term ◽  
Isolated Rat Hepatocytes ◽  
Fatty Acid Release ◽  
14Co2 Production ◽  
Necrosis Factor ◽  
Isolated Rat

Tumour necrosis factor (TNF) did not stimulate lipolysis in isolated rat adipocytes, though preincubation with TNF increased adrenaline-stimulated fatty acid release. Glycogenolysis, gluconeogenesis and ketogenesis in isolated rat hepatocytes were not influenced by TNF in short-term (30-60 min) incubations. TNF stimulated 14CO2 production from [U-14C]glucose in rat hemidiaphragm preparations, but lactate production and alanine release were not significantly altered. It is concluded that TNF does not regulate short-term metabolism in adipocytes, hepatocytes and muscle preparations in the manner of a catabolic hormone.

Monooxygenase and glucuronyltransferase activities in short term cultures of isolated rat hepatocytes

FEBS Letters ◽  
1979 ◽  
Vol 98 (1) ◽  
pp. 203-206 ◽  
Author(s):  
L.R. Schwarz ◽  
R. Götz ◽  
Th. Wolff ◽  
F.J. Wiebel
Keyword(s):  
Rat Hepatocytes ◽  
Short Term ◽  
Isolated Rat Hepatocytes ◽  
Isolated Rat

Elevated Soluble Tumour Necrosis Factor Receptor Serum Concentrations and Short-Term Mortality in Liver Cirrhosis without Acute Infections

Digestion ◽  
2000 ◽  
Vol 62 (1) ◽  
pp. 44-51 ◽  
Author(s):  
Christoph Reichel ◽  
Thomas Sudhop ◽  
Barbara Braun ◽  
Karl-Anton Kreuzer ◽  
Corinna Hahn ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Tumour Necrosis Factor ◽  
Tumour Necrosis ◽  
Tumour Necrosis Factor Receptor ◽  
Serum Concentrations ◽  
Short Term ◽  
Acute Infections ◽  
Short Term Mortality ◽  
Necrosis Factor

Apoptosis in cultured rat hepatocytes: The effects of tumour necrosis factor α and interferon γ

1991 ◽  
Vol 165 (3) ◽  
pp. 247-253 ◽  
Author(s):  
Tadashi Shinagawa ◽  
Kentaro Yoshioka ◽  
Shinichi Kakumu ◽  
Takaji Wakita ◽  
Tetsuya Ishikawa ◽  
...  
Keyword(s):  
Tumour Necrosis Factor ◽  
Tumour Necrosis ◽  
Rat Hepatocytes ◽  
Interferon Γ ◽  
Tumour Necrosis Factor Α ◽  
Cultured Rat Hepatocytes ◽  
Factor Α ◽  
Necrosis Factor

scholarly journals Short-term effects of insulin and glucagon on lipid synthesis in isolated rat hepatocytes

FEBS Letters ◽  
1978 ◽  
Vol 95 (2) ◽  
pp. 326-330 ◽  
Author(s):  
Math J.H. Geelen ◽  
Anton C. Beynen ◽  
Renata Z. Christiansen ◽  
Mimi J. Lepreau-Jose ◽  
David M. Gibson
Keyword(s):  
Lipid Synthesis ◽  
Rat Hepatocytes ◽  
Short Term ◽  
Isolated Rat Hepatocytes ◽  
Isolated Rat ◽  
Short Term Effects

Tumour necrosis factor-alpha uncouples respiration in isolated rat mitochondria

Cytokine ◽  
2003 ◽  
Vol 22 (1-2) ◽  
pp. 1-4 ◽  
Author(s):  
Sı́lvia Busquets ◽  
Xavier Aranda ◽  
Miquel Ribas-Carbó ◽  
Joaquim Azcon-Bieto ◽  
Francisco J. López-Soriano ◽  
...  
Keyword(s):  
Tumour Necrosis Factor ◽  
Tumour Necrosis ◽  
Tumour Necrosis Factor Alpha ◽  
Necrosis Factor Alpha ◽  
Factor Alpha ◽  
Necrosis Factor ◽  
Isolated Rat
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