scholarly journals Effect of insulin, catecholamines and calcium ions on phospholipid metabolism in isolated white fat-cells

1980 ◽  
Vol 192 (3) ◽  
pp. 989-989
Keyword(s):  
Calcium Ions ◽  
Phospholipid Metabolism ◽  
Fat Cells ◽  
White Fat

scholarly journals Effect of insulin, catecholamines and calcium ions on phospholipid metabolism in isolated white fat-cells

1980 ◽  
Vol 186 (3) ◽  
pp. 781-789 ◽  
Author(s):  
J. Adolfo García-Sáinz ◽  
John N. Fain
Keyword(s):  
Fatty Acids ◽  
Phosphatidic Acid ◽  
Inhibitory Effect ◽  
Phospholipid Metabolism ◽  
Ionophore A23187 ◽  
Fat Cells ◽  
Adrenergic Stimulation ◽  
White Fat ◽  
Adrenergic Activation ◽  
Rat Fat Cells

The incorporation of [32P]Pi into phosphatidylinositol by rat fat-cells was markedly increased in the presence of adrenaline. Phosphatidic acid labelling was also increased, but to a lesser extent. These effects are due to α1-adrenergic stimulation since they were unaffected by propranolol, blocked by α-blockers in the potency order prazosin«phentolamine<yohimbine and mimicked by methoxamine. The α-adrenergic stimulation of phosphatidylinositol labelling did not require extracellular Ca2+, which supports the hypothesis that an increased turnover of phosphatidylinositol is involved in α-adrenergic activation of Ca2+ entry. Insulin and the ionophore A23187 gave a small increase in 32P labelling of phosphatidylinositol in Ca2+-free medium containing 1mm-EGTA. The increases due to insulin or ionophore A23187 were abolished if 2.5mm-Ca2+ was added to medium containing EGTA. However, the increases in labelling of phosphatidylinositol due to α-adrenergic amines were still evident in medium containing EGTA and Ca2+. Lipolytic agents such as corticotropin, dibutyryl cyclic AMP, adrenaline in the presence of phentolamine and isoproterenol decreased [32P]Pi incorporation into phosphatidylinositol, phosphatidylethanolamine and phosphatidic acid. This inhibitory effect may be secondary to accumulation of intracellular unesterified fatty acids, since it was decreased by incubating fewer cells in medium with 6 rather than 3% albumin and was restored by the addition of oleate to the medium. The incorporation of [32P]Pi into phosphatidylcholine was unaffected by lipolytic agents. The data suggest that there is an inhibition of the synthesis of certain phospholipids in the presence of lipolytic agents, which may be secondary to intracellular accumulation of unesterified fatty acids.

Chondroid Lipoma, A Tumor of White Fat Cells

1995 ◽  
Vol 19 (11) ◽  
pp. 1272-1276 ◽  
Author(s):  
Gunnlaugur P. Nielsen ◽  
Andrew E. Rosenberg
Keyword(s):  
Fat Cells ◽  
Chondroid Lipoma ◽  
White Fat

Nonselective Cation Channels in Brown and White Fat Cells

1993 ◽  
pp. 201-211 ◽  
Author(s):  
Ari Koivisto ◽  
Elisabeth Dotzler ◽  
Ulrich Ruß ◽  
Jan Nedergaard ◽  
Detlef Siemen
Keyword(s):  
Cation Channels ◽  
Fat Cells ◽  
Nonselective Cation Channels ◽  
White Fat

scholarly journals Dlgap1 negatively regulates browning of white fat cells through effects on cell proliferation and apoptosis

2020 ◽  
Vol 19 (1) ◽  
Author(s):  
Ju Zhang ◽  
Jie Yang ◽  
Nan Yang ◽  
Jianfei Ma ◽  
Datong Lu ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Fat Cells ◽  
Proliferation And Apoptosis ◽  
White Fat

Regulation of beta3-adrenoceptor expression in white fat cells

1995 ◽  
Vol 9 (2) ◽  
pp. 97-106 ◽  
Author(s):  
D. Langin ◽  
G. Tavernier ◽  
M. Lafontan
Keyword(s):  
Fat Cells ◽  
White Fat

Response of isolated white fat cells to anti-malarial drugs

1973 ◽  
Vol 22 (23) ◽  
pp. 3025-3032 ◽  
Author(s):  
Richard H. Pointer ◽  
John N. Fain
Keyword(s):  
Fat Cells ◽  
White Fat

scholarly journals Influence of Extracellular Matrix on the Lipogenesis of Cultured White Fat Cells.

1998 ◽  
Vol 31 (1) ◽  
pp. 9-15 ◽  
Author(s):  
Nobuhisa Yonemitsu ◽  
Fernando Bittinger ◽  
Thomas Gerheld ◽  
Hajime Sugihara ◽  
Christian Mittermayer ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Fat Cells ◽  
White Fat
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