scholarly journals Influence of Extracellular Matrix on the Lipogenesis of Cultured White Fat Cells.

1998 ◽  
Vol 31 (1) ◽  
pp. 9-15 ◽  
Author(s):  
Nobuhisa Yonemitsu ◽  
Fernando Bittinger ◽  
Thomas Gerheld ◽  
Hajime Sugihara ◽  
Christian Mittermayer ◽  
...  
1995 ◽  
Vol 19 (11) ◽  
pp. 1272-1276 ◽  
Author(s):  
Gunnlaugur P. Nielsen ◽  
Andrew E. Rosenberg
Keyword(s):  

1993 ◽  
pp. 201-211 ◽  
Author(s):  
Ari Koivisto ◽  
Elisabeth Dotzler ◽  
Ulrich Ruß ◽  
Jan Nedergaard ◽  
Detlef Siemen

2020 ◽  
Vol 19 (1) ◽  
Author(s):  
Ju Zhang ◽  
Jie Yang ◽  
Nan Yang ◽  
Jianfei Ma ◽  
Datong Lu ◽  
...  

1995 ◽  
Vol 9 (2) ◽  
pp. 97-106 ◽  
Author(s):  
D. Langin ◽  
G. Tavernier ◽  
M. Lafontan
Keyword(s):  

1973 ◽  
Vol 22 (23) ◽  
pp. 3025-3032 ◽  
Author(s):  
Richard H. Pointer ◽  
John N. Fain
Keyword(s):  

1987 ◽  
Vol 253 (6) ◽  
pp. C783-C791 ◽  
Author(s):  
F. D. DeMartinis ◽  
K. T. Ashkin ◽  
K. T. Lampe

Rhodamine 123 and epifluorescence microscopy revealed a significant portion of the fat cell's mitochondria existed in the form of clusters or aggregates, whereas the remainder were scattered about the cytoplasm. The aggregates were variable in size and number and apparently bore no fixed relationship to the nucleus or to each other. Mitochondrial clusters were seen in vivo in rat and mouse adipocytes of the mesenteric and epididymal depots, in excised tissue pieces of other depots, and in isolated fat cells. Physiological factors investigated such as species type (rat, mouse, rabbit, dog), sex, age, depot location (superficial vs. deep), fat cell size, hypercholesterolemia, and 24-h fasting had no apparent effect on cluster prevalence or size. Similar aggregates were not visible in several cultured cell lines studied nor in various non-fat cells, capillary endothelial cells, or nerve fibers contained within adipose depots examined. These results indicate that mitochondrial clusters exist naturally in mammalian white fat cells and conclude that they represent a form of cytoplasmic organization whose purposes are not well understood.


2016 ◽  
Vol 27 (16) ◽  
pp. 2523-2527 ◽  
Author(s):  
Paul Cohen ◽  
Bruce M. Spiegelman

The worldwide epidemic of obesity and type 2 diabetes has greatly increased interest in the biology and physiology of adipose tissues. Adipose (fat) cells are specialized for the storage of energy in the form of triglycerides, but research in the last few decades has shown that fat cells also play a critical role in sensing and responding to changes in systemic energy balance. White fat cells secrete important hormone-like molecules such as leptin, adiponectin, and adipsin to influence processes such as food intake, insulin sensitivity, and insulin secretion. Brown fat, on the other hand, dissipates chemical energy in the form of heat, thereby defending against hypothermia, obesity, and diabetes. It is now appreciated that there are two distinct types of thermogenic fat cells, termed brown and beige adipocytes. In addition to these distinct properties of fat cells, adipocytes exist within adipose tissue, where they are in dynamic communication with immune cells and closely influenced by innervation and blood supply. This review is intended to serve as an introduction to adipose cell biology and to familiarize the reader with how these cell types play a role in metabolic disease and, perhaps, as targets for therapeutic development.


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