scholarly journals 14α-Hydroxyoestrone, a new oestrogen metabolite

1967 ◽  
Vol 105 (3) ◽  
pp. 971-978 ◽  
Author(s):  
R. Knuppen ◽  
O. Haupt ◽  
H. Breuer
Keyword(s):  
Adrenal Glands ◽  
Chemical Properties ◽  
Crystalline Form ◽  
Physical And Chemical Properties ◽  
Physical And Chemical ◽  
And Chemical Properties

1. Incubation of oestrone with ox adrenal glands leads to the formation of two main metabolites, one of which has recently been identified as 15α-hydroxyoestrone; the second metabolite (Oe-5) has now been obtained in crystalline form and identified as the hitherto unknown 14α-hydroxyoestrone. 2. The identity of compound Oe-5 with 14α-hydroxyoestrone was confirmed conclusively by comparison with 14α-hydroxyoestrone that was synthesized by pyrolytic aromatization of 14α-hydroxyandrosta-1,4-diene-3,17-dione. 3. The physical and chemical properties as well as the oestrogenic activity of 14α-hydroxyoestrone are described. 4. The biogenesis and metabolism of 14α-hydroxyoestrone were studied in various tissue preparations.

The production of alamethicins by Trichoderma spp.

1987 ◽  
Vol 33 (7) ◽  
pp. 619-625 ◽  
Author(s):  
D. Brewer ◽  
F. G. Mason ◽  
A. Taylor
Keyword(s):  
Shake Flask ◽  
Chemical Properties ◽  
Potassium Nitrate ◽  
Crystalline Form ◽  
Physical And Chemical Properties ◽  
Single Spore ◽  
Trichoderma Spp ◽  
Synthetic Media ◽  
Physical And Chemical ◽  
And Chemical Properties

The production of polypeptides containing a high percentage of 2-methylalanine residues by a number of isolates of Trichoderma spp. has been examined. It has been shown that good yields (0.5–1.0 g L−1) can be achieved on synthetic media provided an insoluble carbohydrate is included and provided single-spore isolates that have this production ability are selected from time to time. Such yields could not be obtained on any single nitrogen source investigated, but a mixture of potassium nitrate, glutamine, and 2-methylalanine was effective. It was shown that at least eight polypeptides were produced in shake-flask or tank fermentation and that the proportions of these metabolites depended on the fermentation temperature, its pH, age, and aeration. Fermentation conditions for enhancing the production (independently) of two of the metabolites at the expense of the others are given. These two metabolites have been obtained in crystalline form and details of some of their physical and chemical properties are given.

The reduction of SU-4885 by adrenal glands and other tissues and its inhibition by ACTH

1968 ◽  
Vol 46 (5) ◽  
pp. 463-469 ◽  
Author(s):  
I. Kraulis ◽  
H. Traikov ◽  
M. P. Li ◽  
C. P. Lantos ◽  
M. K. Birmingham
Keyword(s):  
Rat Liver ◽  
Incubation Medium ◽  
Liver Tissue ◽  
Adrenal Glands ◽  
Rat Kidney ◽  
Chemical Properties ◽  
Physical And Chemical Properties ◽  
Physical And Chemical ◽  
And Chemical Properties

Rat adrenal glands convert 2-methyl-1,2-bis(3-pyridyl)-1-propanone (SU-4885) in vitro to a product with physical and chemical properties indicating the reduction to 2-methyl-1,2-bis(3-pyridyl)-1-propanol. The same compound is also formed by the reduction of SU-4885 with NaBH4. The reduction of SU-4885 also occurs in the presence of frog adrenal, rat kidney, and most actively, rat liver tissue, and depends on the concentration of SU-4885 in the incubation medium. Added deoxycorticosterone, at the concentration used, had no effect, but ACTH inhibited the reduction by both adrenal and liver tissue.

Statistical criteria of stellar population types

1966 ◽  
Vol 24 ◽  
pp. 101-110
Author(s):  
W. Iwanowska
Keyword(s):  
Stellar Population ◽  
Chemical Properties ◽  
Spectrophotometric Study ◽  
Physical And Chemical Properties ◽  
Population Type ◽  
The Galaxy ◽  
Distribution Parameters ◽  
Physical And Chemical ◽  
Statistical Criteria ◽  
And Chemical Properties

In connection with the spectrophotometric study of population-type characteristics of various kinds of stars, a statistical analysis of kinematical and distribution parameters of the same stars is performed at the Toruń Observatory. This has a twofold purpose: first, to provide a practical guide in selecting stars for observing programmes, second, to contribute to the understanding of relations existing between the physical and chemical properties of stars and their kinematics and distribution in the Galaxy.

Response of corn (Zea mays L.) to various organic-based fertilizers in marginal upland of Sta. Rita, Samar

2017 ◽  
pp. 31-43
Author(s):  
Berta Ratilla ◽  
Loreme Cagande ◽  
Othello Capuno
Keyword(s):  
Block Design ◽  
Management Strategies ◽  
Chemical Properties ◽  
Organic Fertilizers ◽  
Growth And Yield ◽  
Physical And Chemical Properties ◽  
Total N ◽  
Randomized Complete Block Design ◽  
Physical And Chemical ◽  
And Chemical Properties

Organic farming is one of the management strategies that improve productivity of marginal uplands. The study aimed to: (1) evaluate effects of various organic-based fertilizers on the growth and yield of corn; (2) determine the appropriate combination for optimum yield; and (3) assess changes on the soil physical and chemical properties. Experiment was laid out in Randomized Complete Block Design, with 3 replications and 7 treatments, namely; T0=(0-0-0); T1=1t ha-1 Evans + 45-30-30kg N, P2O5, K2O ha-1; T2=t ha-1 Wellgrow + 45-30-30kg N, P2O5, K2O ha-1; T3=15t ha-1 chicken dung; T4=10t ha-1 chicken dung + 45-30-30kg N, P2O5, K2O ha-1; T5=15t ha-1 Vermicast; and T6=10t ha-1 Vermicast + 45-30-30kg N, P2O5, K2O ha-1. Application of organic-based fertilizers with or without inorganic fertilizers promoted growth of corn than the control. But due to high infestation of corn silk beetle(Monolepta bifasciata Horns), its grain yield was greatly affected. In the second cropping, except for Evans, any of these fertilizers applied alone or combined with 45-30-30kg N, P2O5, K2O ha-1 appeared appropriate in increasing corn earyield. Soil physical and chemical properties changed with addition of organic fertilizers. While bulk density decreased irrespective of treatments, pH, total N, available P and exchangeable K generally increased more with chicken dung application.

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