scholarly journals REGULATION OF ASCORBIC ACID AND OF XYLULOSE SYNTHESIS IN RAT-LIVER EXTRACTS. THE EFFECT OF STARVATION ON THE ENZYMES OF THE GLUCURONIC ACID PATHWAY

1965 ◽  
Vol 95 (2) ◽  
pp. 354-362 ◽  
Author(s):  
F STIRPE ◽  
M COMPORTI
1965 ◽  
Vol 97 (2) ◽  
pp. 561-564 ◽  
Author(s):  
F Stirpe ◽  
M Comporti

1. The synthesis of l-ascorbic acid and of l-xylulose from d-glucuronolactone, d-glucuronate, l-gulonate and l-gulonolactone has been studied with liver extracts from normal and alloxan-diabetic rats. 2. In diabetic animals the synthesis of ascorbic acid is impaired, and more from glucuronolactone and glucuronate than from gulonate and gulonolactone, whereas the formation of xylulose from gulonate and gulonolactone is enhanced. These changes are reversed by insulin therapy. 3. The activity of the NAD-linked gulonate dehydrogenase is enhanced during diabetes.


1959 ◽  
Vol 234 (2) ◽  
pp. 250-253
Author(s):  
Frank Eisenberg ◽  
Peter G. Dayton ◽  
J.J. Burns

2018 ◽  
Vol 166 (4) ◽  
pp. 979-995 ◽  
Author(s):  
Vanessa Galli ◽  
Rafael S. Messias ◽  
Frank Guzman ◽  
Ellen C. Perin ◽  
Rogério Margis ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document