scholarly journals Ribonuclease activity in the rat mammary gland during pregnancy, lactation and mammary involution

1961 ◽  
Vol 78 (3) ◽  
pp. 500-504 ◽  
Author(s):  
T F Slater
Keyword(s):  
Mammary Gland ◽  
Ribonuclease Activity ◽  
Mammary Involution ◽  
Rat Mammary Gland

scholarly journals Lysosomal enzyme changes in enforced mammary-gland involution

1965 ◽  
Vol 97 (2) ◽  
pp. 518-522 ◽  
Author(s):  
AL Greenbaum ◽  
TF Slater ◽  
DY Wang
Keyword(s):  
Mammary Gland ◽  
Rapid Decrease ◽  
Mammary Involution ◽  
Mammary Gland Involution ◽  
Reserpine Treatment ◽  
Histological Appearance ◽  
Antihistamine Drug ◽  
Rat Mammary Gland ◽  
Early Phases ◽  
Enzyme Changes

1. Changes occurring in the activities and latency of acid ribonuclease and beta-glucuronidase have been studied in rat mammary gland during the early phases of mammary involution. 2. It was found that there were rapid increases in the proportions of both enzymes in the; free' (i.e. unsedimentable) form. The total activities of both enzymes did not show the rapid decrease characteristic of most other enzymes studied during mammary-gland involution. 3. The effects of pretreating the rats with reserpine or the antihistamine drug Phenergan on these lysosomal changes was studied. Neither treatment affected the enzymic redistribution that occurs during early involution. 4. It was concluded that lysosomal rupture occurs as an early manifestation of mammary-gland involution. Although reserpine treatment preserves the histological appearance of the gland and, apparently, inhibits involution, this drug did not prevent the lysosomal changes normally found in suspensions.

scholarly journals Almost Exclusive Androgenic Action of Dehydroepiandrosterone in the Rat Mammary Gland

Endocrinology ◽  
1998 ◽  
Vol 139 (2) ◽  
pp. 753-764 ◽  
Author(s):  
Antigone Sourla ◽  
Céline Martel ◽  
Claude Labrie ◽  
Fernand Labrie
Keyword(s):  
Mammary Gland ◽  
Rat Mammary Gland

scholarly journals Association of cellular and molecular responses in the rat mammary gland to 17β-estradiol with susceptibility to mammary cancer

BMC Cancer ◽  
2013 ◽  
Vol 13 (1) ◽  
Author(s):  
Lina Ding ◽  
Yang Zhao ◽  
Christopher L Warren ◽  
Ruth Sullivan ◽  
Kevin W Eliceiri ◽  
...  
Keyword(s):  
Mammary Gland ◽  
Mammary Cancer ◽  
Molecular Responses ◽  
17Β Estradiol ◽  
Rat Mammary Gland
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