Cystatins may confer viral resistance in plants by inhibition of a virus-induced cell death phenomenon in which cysteine proteinases are active: cloning and molecular characterization of a cDNA encoding cysteine-proteinase inhibitor (celostatin) from Celosia cristata (crested cock's comb)

2005 ◽  
Vol 42 (3) ◽  
pp. 197 ◽  
Author(s):  
Ittiaparambu Mana Santha ◽  
Ashraf Gholizadeh ◽  
Bahram Baghban Kohnehrouz ◽  
Madan Lal Lodha ◽  
Harish Chander Kapoor
Keyword(s):  
Cell Death ◽  
Molecular Characterization ◽  
Proteinase Inhibitor ◽  
Cysteine Proteinase ◽  
Viral Resistance ◽  
Cysteine Proteinase Inhibitor ◽  
Cysteine Proteinases ◽  
Celosia Cristata

Molecular characterization of a cysteine proteinase inhibitor, PgCPI, from Panax ginseng C. A. Meyer

2010 ◽  
Vol 32 (5) ◽  
pp. 961-970 ◽  
Author(s):  
Dae-Young Jung ◽  
Ok Ran Lee ◽  
Yu-Jin Kim ◽  
Jung-Hye Lee ◽  
Rama Krishna Pulla ◽  
...  
Keyword(s):  
Molecular Characterization ◽  
Panax Ginseng ◽  
Proteinase Inhibitor ◽  
Cysteine Proteinase ◽  
Cysteine Proteinase Inhibitor

scholarly journals Expression of Cysteine Proteinases Cathepsins B and K and of Cysteine Proteinase Inhibitor Cystatin C in Giant Cell Tumor of Tendon Sheath

2001 ◽  
Vol 14 (4) ◽  
pp. 318-324 ◽  
Author(s):  
Torsten Hansen ◽  
Peter K Petrow ◽  
Andreas Gaumann ◽  
Gernot M Keyszer ◽  
Mike Otto ◽  
...  
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Cystatin C ◽  
Proteinase Inhibitor ◽  
Cysteine Proteinase ◽  
Tendon Sheath ◽  
Cell Tumor ◽  
Cysteine Proteinase Inhibitor ◽  
Cysteine Proteinases

Localization of cysteine proteinases and an endogenous cysteine proteinase inhibitor in cultured muscle cells

1985 ◽  
Vol 13 (6) ◽  
pp. 1018-1021 ◽  
Author(s):  
J. W. C. BIRD ◽  
L. WOOD ◽  
I. SOHAR ◽  
E. FEKETE ◽  
R. COLELLA ◽  
...  
Keyword(s):  
Proteinase Inhibitor ◽  
Cysteine Proteinase ◽  
Muscle Cells ◽  
Cysteine Proteinase Inhibitor ◽  
Cysteine Proteinases

Involvement of cysteine proteinases in excystment of Paragonimus ohirai metacercariae induced by sodium cholate and A23187

2003 ◽  
Vol 77 (1) ◽  
pp. 21-26 ◽  
Author(s):  
T. Ikeda
Keyword(s):  
Proteinase Inhibitor ◽  
Proteinase Inhibitors ◽  
Cysteine Proteinase ◽  
Serine Proteinase ◽  
Sodium Cholate ◽  
Cysteine Proteinase Inhibitor ◽  
Cysteine Proteinases ◽  
Serine Proteinase Inhibitor ◽  
Similar Activity

AbstractThe involvement of intrinsic proteinases in the excystment of Paragonimus ohirai metacercariae was studied in in vitro excystment induced by sodium (Na) cholate, a bile salt and A23187, a Ca2+ ionophore. The effects of various proteinase inhibitors on the in vitro excystment were examined and similar inhibitory profiles were obtained. Benzyloxycarbonyl-L-leucyl-L-leucinal (Z-Leu-Leu-H), a cysteine proteinase inhibitor and 4-(2-aminoethyl)-benzenesulfonyl fluoride (Pefabloc SC), a serine proteinase inhibitor completely inhibited excystment, while L-3-carboxy-2,3-trans-epoxypropionyl-leucylamido (4-guanidino)-butane (E-64), a cysteine proteinase inhibitor and leupeptin, a cysteine/serine proteinase inhibitor permitted partial excystment at a lower rate, but inhibited it from proceeding from the partial excystment stage. In secretions released from metacercariae during excystment, proteinase activities detected towards various fluorogenic peptidyl substrates were almost completely inhibited by Z-Leu-Leu-H and E-64, but not by Pefabloc SC. Sodium cholate induced a higher secretion of cysteine proteinases and a higher rate of excystment than A23187. Profiles of cysteine proteinase activities towards five peptidyl substrates detected were markedly different among the two secretions and the lysate of newly excysted juveniles. Newly excysted juveniles released cysteine proteinases with similar activity profiles and levels to metacercariae induced by Na cholate-incubation, whereas the release of cysteine proteinases was reduced compared with metacercariae induced by A23187-incubation. These results provide valuable information about the involvement of intrinsic proteinases in metacercarial excystment.

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