Carotenoids and related compounds. Part XIX. The geometrical isomers of 2- and 3-methyl-5-phenylpenta-2,4-dienoic acid and their methyl esters

1968 ◽  
pp. 1997 ◽  
Author(s):  
Gerald Pattenden ◽  
B. C. L. Weedon
Keyword(s):  
Methyl Esters ◽  
Dienoic Acid ◽  
Geometrical Isomers ◽  
Related Compounds

ChemInform Abstract: Synthesis of Substituted Hexa-3,5-dienoic Acid Methyl Esters from Conjugated Dienones.

ChemInform ◽  
2010 ◽  
Vol 32 (43) ◽  
pp. no-no
Author(s):  
Rishan Lang Nongkhlaw ◽  
Ridaphun Nongrum ◽  
Bekington Myrboh
Keyword(s):  
Methyl Esters ◽  
Dienoic Acid ◽  
Acid Methyl

A ROLE FOR PROSTAGLANDINS IN DECIDUALIZATION OF THE RAT UTERUS

1981 ◽  
Vol 89 (1) ◽  
pp. 25-33 ◽  
Author(s):  
NICOLE SANANÈS ◽  
ETIENNE-EMILE BAULIEU ◽  
CLAUDE LE GOASCOGNE
Keyword(s):  
Arachidonic Acid ◽  
Dienoic Acid ◽  
Inhibitory Effect ◽  
Rat Uterus ◽  
Hormonal Stimulation ◽  
Immature Rats ◽  
Decidual Reaction ◽  
Dose Dependent ◽  
Related Compounds

The deciduogenic action of various kinds of prostaglandin (PG), i.e. PGE1, PGE2, PGF2α and PGI2, methylated prostaglandins (15-met-PGE1, 15-met-PGE2 and 15-met-PGF2α), PGF2α-13-dehydro analogues (13-DH-PGF2α, ent-15-epi-13-DH-PGF2α), endoperoxide analogues (15S)-hydroxy-9α,11α-(epoxymethano)-prosta-5Z,13E-dienoic acid (U 44069) and (15S)-hydroxy-11α,9α-(epoxymethano)-prosta-5Z,13E-dienoic acid (U 46619), and of the prostaglandin precursor, arachidonic acid, has been demonstrated after intraluminal instillation of these compounds into the uterus of immature rats sensitized with progesterone alone. Under this minimal hormonal stimulation, in which a trauma (a scratch) of the endometrium is required to induce the decidual response, all these compounds elicited the formation of deciduomata, substantiating the suggestion that the scratch-induced decidual reaction is mediated through release of prostaglandin. Confirmation was obtained through the effect of indomethacin and cortisol, both of which decreased the decidual response brought on by a scratch or by arachidonic acid, whereas the effect of PGF2α was decreased by indomethacin but not by cortisol. Histamine, thromboxane B2, and oleic, palmitic and homo-γ-linolenic acids were not deciduogenic. A dose-dependent inhibitory effect of indomethacin on deciduoma formation by instillation of oil into animals sensitized by progesterone plus oestradiol was also observed. The results support the proposal that the decidual reaction involves prostaglandins and we suggest that the deciduoma is a valuable model for studying the action of prostaglandin-related compounds.

scholarly journals Streamlined Methods for the Resolution and Quantification of Fatty Acids Including Trans Fatty Acid Isomers in Food Products by Gas Chromatography

2009 ◽  
Vol 92 (5) ◽  
pp. 1301-1309 ◽  
Author(s):  
Pierre-Alain Golay ◽  
Francesca Giuffrida ◽  
Fabiola Dionisi ◽  
Frédéric Destaillats
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
High Resolution ◽  
Methyl Esters ◽  
Direct Methods ◽  
Food Products ◽  
Response Factors ◽  
Geometrical Isomers ◽  
Cost Constraints ◽  
Wide Range

Abstract To support labeling, claims, and authenticity of food products, industry needs reliable methods for the analysis of fatty acids, including Trans fatty acids (TFA). In finished products, precise quantification of TFA can be problematic due to the occurrence of various positional and geometrical isomers originating from different sources, such as animal fats or processed vegetable oils and fats. The risk of underestimating TFA amounts is particularly high when inappropriate GC conditions are used. Complex sample preparation procedures involving purification of TFA isomers by silver ion chromatography have been well-documented and used for research purposes. However, in the food industry, time and cost constraints do not permit multiple analytical steps; therefore, streamlined methods are necessary. Direct methods include preparation of fatty acid methyl esters directly from food samples without prior extraction. The appropriate resolution is obtained using high-resolution GC with a highly polar 100 m capillary column, and quantification is achieved using experimentally determined response. We found that it is possible to quantify TFA in the range of 0.01 to 5.00 g/100 g of lipids in a wide range of food products. In addition, the use of direct transmethylation, response factors, and high-resolution GC allow accurate quantification of other fatty acids, including polyunsaturated and long-chain polyunsaturated fatty acids.

Synthesis of substituted hexa-3,5-dienoic acid methyl esters from conjugated dienones

2001 ◽  
pp. 1300-1303 ◽  
Author(s):  
Rishan Lang Nongkhlaw ◽  
Ridaphun Nongrum ◽  
Bekington Myrboh
Keyword(s):  
Methyl Esters ◽  
Dienoic Acid ◽  
Acid Methyl
Sign in / Sign up

Export Citation Format

Share Document