scholarly journals RNA BioMolecular Electronics: towards new tools for biophysics and biomedicine

2021 ◽  
Author(s):  
Keshani G. Gunasinghe Pattiya Arachchillage ◽  
Subrata Chandra ◽  
Angela Piso ◽  
Tiba Qattan ◽  
Juan M. Artes Vivancos
Keyword(s):  
Biomolecular Electronics ◽  
Potential Applications ◽  
Future Potential ◽  
Electrical Study

Nanoscience has enabled the electrical study of individual biomolecules. This perspective presents the nascent field of RNA BioMolecular Electronics, overviewing the main developments and exploring recent and future potential applications.

The electronic applications of stable diradicaloids: present and future

2018 ◽  
Vol 6 (42) ◽  
pp. 11232-11242 ◽  
Author(s):  
Xiaoguang Hu ◽  
Wenxiang Wang ◽  
Dongsheng Wang ◽  
Yonghao Zheng
Keyword(s):  
Field Effect ◽  
High Performance ◽  
Field Effect Transistor ◽  
Logic Gates ◽  
Linear Optics ◽  
Non Linear Optics ◽  
Potential Applications ◽  
Future Potential ◽  
Effect Transistor ◽  
Organic Batteries

Diradicaloids are promising materials for organic electronics and nonlinear optics due to their unique optical, electronic and magnetic properties. High performance organic field-effect transistor and photodetector based on diradicaloids have been achieved. Future potential applications in organic batteries, memory, logic gates and non-linear optics are expected.

scholarly journals Renal Sympathetic Denervation for the Treatment of Difficult-to-Control or Resistant Hypertension

2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
Vasilios Papademetriou ◽  
Michalis Doumas ◽  
Konstantinos Tsioufis
Keyword(s):  
Resistant Hypertension ◽  
Antihypertensive Drugs ◽  
Sympathetic Denervation ◽  
Renal Sympathetic Denervation ◽  
Major Health Problem ◽  
Number Of Patients ◽  
Recovery Times ◽  
Potential Applications ◽  
Future Potential ◽  
Renal Sympathetic

Hypertension represents a major health problem with an appalling annual toll. Despite the plethora of antihypertensive drugs, hypertension remains resistant in a considerable number of patients, thus creating the need for alternative strategies, including interventional approaches. Recently, catheter-based renal sympathetic denervation has been shown to be fairly safe and effective in patients with resistant hypertension. Pathophysiology of kidney function, interaction and crosstalk between the kidney and the brain, justifies the use of renal sympathetic denervation in the treatment of hypertension. Data from older studies have shown that sympathectomy has effectively lowered blood pressure and prolonged life expectancy of hypertensive patients, but at considerable cost. Renal sympathetic denervation is devoid of the adverse effects of surgical sympathectomy, due to its localized nature, is minimally invasive, and provides short procedural and recovery times. This paper outlines the pathophysiological background for renal sympathetic denervation, describes the past and the present of this interventional approach, and considers several future potential applications.

Qualitative Approaches in Craniofacial Research

2009 ◽  
Vol 46 (3) ◽  
pp. 245-251 ◽  
Author(s):  
Pauline A. Nelson
Keyword(s):  
Qualitative Methods ◽  
Field Research ◽  
Evidence Base ◽  
Professional Beliefs ◽  
Qualitative Approaches ◽  
Research With Children ◽  
The Social ◽  
Potential Applications ◽  
Future Potential ◽  
Research Tools

This article proposes the customary use of qualitative methods as complementary research tools to enhance the evidence base in the craniofacial field. The recognition given to qualitative approaches in other healthcare areas and their value in enhancing understanding of lay and professional beliefs and behaviors is contrasted with the paucity of qualitative studies to date in the craniofacial field. Research tools from the qualitative repertoire are briefly introduced and their underpinning principles are explained. The contribution made to research with children and families in wider healthcare areas and in the craniofacial field to date is outlined. Future potential applications of these methods to craniofacial research are discussed. It is suggested that qualitative methods be integrated into craniofacial research as part of the standard toolbox of inquiry, and that interdisciplinary collaborations with colleagues from the social sciences appropriately skilled in the methods should be developed.

scholarly journals Physicochemical and Biological Properties of Graphene-Oxide-Coated Metallic Materials

Materials ◽  
2021 ◽  
Vol 14 (19) ◽  
pp. 5752
Author(s):  
Aleksandra Poniatowska ◽  
Paulina Anna Trzaskowska ◽  
Maciej Trzaskowski ◽  
Tomasz Ciach
Keyword(s):  
Graphene Oxide ◽  
Biological Properties ◽  
Negative Control ◽  
L929 Cells ◽  
Potential Applications ◽  
Direct Cell ◽  
Future Potential ◽  
The Stability ◽  
Modified Hummers Method ◽  
Modification Of The Surface

In this article, we present graphene oxide (produced by a modified Hummers’ method) coatings obtained using two different methods: electrophoretic deposition on 316L stainless steel and chemical modification of the surface of gold applied to the steel. The coating properties were characterized by microscopic and spectrometric techniques. The contact angle was also determined, ranging from 50° to 70°. Our results indicated that GO coatings on steel and gold were not toxic towards L929 cells in a direct cell adhesion test—on all tested materials, it was possible to observe the growth of L929 cells during 48 h of culture. The lack of toxic effect on cells was also confirmed in two viability tests, XTT and MTT. For most of the tested materials, the cell viability was above 70%. They showed that the stability of the coating is the crucial factor for such GO coatings, and prove that GO in the form of coating is non-toxic; however, it can show toxicity if detached from the surface. The obtained materials also did not show any hemolytic properties, as the percentage of hemolysis was on the level of the negative control, which is very promising in the light of future potential applications.

Advances in the design of optical see-through displays

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Yao Zhou ◽  
Jufan Zhang ◽  
Fengzhou Fang
Keyword(s):  
Design Principles ◽  
Manufacturing Processes ◽  
Performance Parameters ◽  
Innovative Technologies ◽  
Potential Applications ◽  
Future Potential ◽  
Systematical Review ◽  
Physical Principles

AbstractDriven by greatly increased applications, the optical see-through displays have been developing rapidly in recent decades. As a result, some innovative technologies have emerged toward making the display more compact and lighter with better performance. This paper serves as a systematical review on the advances in developing optical see-through displays, including the physical principles, optical configurations, performance parameters and manufacturing processes. The design principles, current challenges, possible solutions and future potential applications are also discussed in the paper.

scholarly journals Impact of IoT Technologies on Smart City Infrastructure: Current Applications and Future Potential

2019 ◽  
Vol 8 (2S11) ◽  
pp. 2387-2391
Keyword(s):  
Internet Of Things ◽  
Smart City ◽  
It Infrastructure ◽  
Government Officials ◽  
It Industry ◽  
Study Approach ◽  
Potential Applications ◽  
Future Potential ◽  
Industrial Level ◽  
The Impact

With the advent of digitization, upcoming technologies like Internet of Things (IOT) are being used by organizations to manage their business, infrastructure as well as assets. In order to make the IT Infrastructure more efficient, upcoming technologies like Internet of things play a very important role as IoT has increased the scale of the storage and the server spaces, improved the internet connectivity thereby leading to a smarter IT infrastructure. Although IoT adoption is taking place rapidly at the enterprise and industrial level; there is a dearth of academic literature in this area. Hence the objective of the paper is to study the adoption of various IoT technologies for smart city infrastructure, understand the impact/benefits of these technologies and propose future potential applications which can be used for smart infrastructure. A case study approach has been adopted for this research wherein various use cases in the IT industry have been analysed with respect to the adoption of IoT technologies 0066or smart city infrastructure and the benefits of the same to the various sectors. The study will be useful for academicians, and practitioners, and Government officials to design and develop solutions for smart city infrastructure that will add to wellbeing of society at large.

scholarly journals Polyploidy in Gymnosperms: Revisited

2005 ◽  
Vol 54 (1-6) ◽  
pp. 59-69 ◽  
Author(s):  
M. Raj Ahuja
Keyword(s):  
Low Frequency ◽  
Current Status ◽  
Chromosome Behavior ◽  
Very Low Frequency ◽  
Juniperus Chinensis ◽  
Wide Range ◽  
Potential Applications ◽  
Future Potential ◽  
Growth Abnormalities ◽  
Fitzroya Cupressoides

Abstract There are only a few natural polyploids in gymnosperms. These have been reported in Ephera spp. (Gnetales), and Juniperus chinensis ‘Pfitzeriana’ (2n = 4x = 44), Fitzroya cupressoides (2n = 4x = 44), and the only hexaploid conifer Sequoia sempervirens (2n = 6x = 66) (Coniferales). Sporadic polyploids and aneuploids occur at a very low frequency in nurseries in conifers, but most of them show growth abnormalities, remain dwarf, and may not reach maturity. One exception is an autotetraploid tree of Larix decidua (2n = 4x = 48) that has survived in a private estate in Denmark. Colchicine-induced polyploids (colchiploids) have been produced in a several genera of conifers, including, Pinus, Picea, and Larix. These colchiploids (Co) were hybridized to untreated diploids to produce C1 and C2 generations to investigate their chromosome behavior. The colchiploids showed a wide range of chromosome variability, ranging from diploids, triploids, and tetraploids, and many were mixoploids. The colchiploids also show growth retardation, remain dwarf, and their future potential applications in forestry remains uncertain. However, genetic variability in the colchiploids still offers prospects for isolating genetically stable new genotypes. Even though polyploidy is rare in extant conifers, is it possible that ancient polyploidy or paleopolyploidy, that is prevalent in angiosperms, has also played a role in the evolution of conifers. In this paper we shall review the current status of polyploidy in gymnosperms.

Anti-Tumor Effects of Melittin and Its Potential Applications in Clinic

2019 ◽  
Vol 20 (3) ◽  
pp. 240-250 ◽  
Author(s):  
Can Lyu ◽  
Fanfu Fang ◽  
Bai Li
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Biological Effects ◽  
Tumor Therapy ◽  
Clinical Applications ◽  
Water Soluble ◽  
Research Progress ◽  
Severe Side Effect ◽  
Potential Applications ◽  
Future Potential

Melittin, a major component of bee venom, is a water-soluble toxic peptide of which a various biological effects have been identified to be useful in anti-tumor therapy. In addition, Melittin also has anti-parasitic, anti-bacterial, anti-viral, and anti-inflammatory activities. Therefore, it is a very attractive therapeutic candidate for human diseases. However, melittin induces extensive hemolysis, a severe side effect that dampens its future development and clinical application. Thus, studies of melittin derivatives and new drug delivery systems have been conducted to explore approaches for optimizing the efficacy of this compound, while reducing its toxicity. A number of reviews have focused on each side, respectively. In this review, we summarize the research progress on the anti-tumor effects of melittin and its derivatives, and discuss its future potential clinical applications.

scholarly journals Diffusion weighted MR imaging

1998 ◽  
Vol 3 (3) ◽  
pp. 4-6
Author(s):  
B. Ramsing ◽  
P. Corr
Keyword(s):  
Mr Imaging ◽  
Diffusion Weighted Imaging ◽  
Molecular Motion ◽  
Diffusion Imaging ◽  
Clinical Applications ◽  
Diffusion Weighted ◽  
Potential Applications ◽  
Technological Developments ◽  
Future Potential ◽  
Physical Principles

Diffusion weighted imaging (DWI) allows the measurement of molecular motion in tissue. This technique has significant clinical applications. Recent technological developments in fast MR imaging have brought diffusion imaging into clinical practice. This review will explain the physical principles, and current and future potential applications of diffusion imaging in medicine.

scholarly journals Microperimetry in Children’s Practice

2021 ◽  
Vol 18 (4) ◽  
pp. 807-814
Author(s):  
R. R. Khubieva
Keyword(s):  
High Efficiency ◽  
Functional Organization ◽  
Light Sensitivity ◽  
Diagnostic Study ◽  
Vision 2020 ◽  
Diagnostic Significance ◽  
Visual Rehabilitation ◽  
Non Invasive ◽  
Potential Applications ◽  
Future Potential

Child health is a global health priority. The program “Elimination of Eliminable Blindness in the World of Vision-2020” gives the fourth place to the problems of pediatric ophthalmopathology and creates targeted programs for their elimination. The introduction of modern equipment in the clinical practice of pediatric ophthalmologists has expanded the boundaries of traditional diagnostics. Microperimetry is an innovative, quantitative, non-invasive diagnostic study aimed at assessing the functional ability of the retina in strict correlation with morphology. Along with the assessment of light sensitivity, the device allows you to measure fixation parameters, which serves as a reliable criterion for its stability and indirectly reflects the functional organization of central vision. In this regard, the literature review presents the results of domestic and foreign researchers who used microperimetric testing as the main or additional research method for diseases of various etiologies, such as hereditary retinal diseases, amblyopia, and nystagmus. Most authors have demonstrated the high diagnostic significance of this method, the ability to assess photosensitivity of the retina, the detection of fixation disorders, such as eccentricity and instability, even in pediatric patients. The use of microperimetry as a new method of treatment for these diseases has also been shown. Visual rehabilitation based on biofeedback provided by this device has shown high efficiency in diseases of the central region. More research remains to be done to determine future potential applications of this technology, in particular in pediatric practice, and to develop the potential of microperimetry as a tool for the visual rehabilitation of patients.

Sign in / Sign up

Export Citation Format

Share Document