On / Off Switchable Physical Stimuli Regulates the Future Direction of Adherent Cellular Fate

Author(s):  
Indong Jun ◽  
Hyung-Seop Han ◽  
Jae Won Lee ◽  
Kyungwoo Lee ◽  
Yu-Chan Kim ◽  
...  

The utilization of cell-manipulating techniques reveals information about biological behaviors suited to address a wide range of questions in the field of life science. Here, we introduced an on/off switchable...

2016 ◽  
Vol 117 (9/10) ◽  
pp. 557-567 ◽  
Author(s):  
Pauline Dewan

Purpose Librarians planning for the future and unsure about the place of books in an age dominated by technology and media need evidence to make sound decisions. Library and information science researchers have studied the impact of pleasure reading on individuals but not on society. The purpose of this paper is to raise awareness about the benefits of recreational reading for societies and to consider the implications of these findings for libraries. Design/methodology/approach Examining a wide range of studies by government bodies, intergovernmental agencies and academics, this paper addresses a gap in the library literature by critically evaluating the combined implications of sources not hitherto viewed together. Findings The more leisure books people read, the more literate they become, and the more prosperous and equitable the society they inhabit. Practical implications Librarians should create a more robust culture of reading and play a stronger advocacy role for books in libraries. Originality/value No one has yet examined government reports about literacy in relation to studies on the impact of pleasure reading. The implications of this combined research highlight the fact that pleasure reading benefits societies as well as individuals, a finding that has significant implications for the future direction of libraries. Decision-makers who need a robust mandate for book-focused resources and services will find supportive statistical evidence in this paper.


2004 ◽  
Vol 5 (2) ◽  
pp. 1-21
Author(s):  
Chong-Ryel Bae

What will the North Korean economy look like a decade from now? Ever since North Korea's implementation of its Economic Management Improvement Measures in July 2002, a wide range of views have been voiced with regard to the future direction of the North Korean economy. This paper discusses what changed and what remained the same during the ten years since the death of Kim Il-Sung in July 1994, after which North Korea began trying to change its economy in accordance with its own version of socialism. The current state of the North Korean economy makes certain things clear. Difficult though it may be to predict how the quantitative aspects of the North Korean economy will change, there is general agreement that it will increasingly become market-oriented. However, there is no agreement on the pace of transition. Will it be a radical bang or a gradual transformation or a third-way. The future direction of the North Korean economy will become more evident over time.


2020 ◽  
pp. 301-323
Author(s):  
Natalya I. Kikilo ◽  

In the Macedonian literary language the analytic da-construction used in an independent clause has a wide range of possible modal meanings, the most common of which are imperative and optative. The present article offers a detailed analysis of the semantics and functions of the Macedonian optative da-construction based on fiction and journalistic texts. The first part of the article deals with the specificities of the optative as a category which primarily considers the subject of a wish. In accordance with the semantic characteristics of this category, optative constructions are used in those discourse text types where the speakers are explicitly designated (the most natural context for the optative is the dialogue). The analysis of the Macedonian material includes instances of atypical usage of the optative da-construction, in which the wish of the subject is not apparent and thereby produces new emotional tonalities perceptible to the reader of a fiction/journalistic text. The study describes Macedonian constructions involving two different verb forms: 1) present tense form (da + praes) and 2) imperfective form (da + impf). These constructions formally designate the hypothetical and counterfactual status of the optative situation, respectively. Thus, the examples in the analysis are ordered according to two types of constructions, which reflect the speaker’s view on the probability of the realisation of his/her wish. Unrealistic wishes can be communicated through the present da-construction, while the imperfective construction denotes situations in which the wish can be realised in the future. The second part of the article is devoted to performative optative da-constructions, which express formulas of speech etiquette, wishes and curses. The analysis demonstrates that these constructions lose their magical functions, when used outside of the ritual context, and begin to function as interjections.


2020 ◽  
Vol 21 (2) ◽  
pp. 153-158 ◽  
Author(s):  
Soung-Hoo Jeon

An allergic reaction to mosquitoes can result in severe or abnormal local or systemic reactions such as anaphylaxis, angioedema, and general urticarial or wheezing. The aim of this review is to provide information on mosquito saliva allergens that can support the production of highly specific recombinant saliva allergens. In particular, candidate allergens of mosquitoes that are well suited to the ecology of mosquitoes that occur mainly in East Asia will be identified and introduced. By doing so, the diagnosis and treatment of patients with severe sensitivity to mosquito allergy will be improved by predicting the characteristics of East Asian mosquito allergy, presenting the future direction of production of recombinant allergens, and understanding the difference between East and West.


NASPA Journal ◽  
2002 ◽  
Vol 39 (2) ◽  
Author(s):  
Larry D. Roper

For the past 18 months the NASPA Journal Editorial Board has been engaged in an ongoing conversation about the future direction of the Journal. Among the issues we have discussed are: What should comprise the content of the Journal?, How do we decide when or if we will move the Journal to an electronic format?, What do our members want in the Journal?, and What type of scholarship should we be publishing? The last question — What type of scholarship should we be publishing? — led to an energetic conversation within the Editorial Board.


2021 ◽  
Vol 11 (14) ◽  
pp. 6246
Author(s):  
Paweł Komorowski ◽  
Patrycja Czerwińska ◽  
Mateusz Kaluza ◽  
Mateusz Surma ◽  
Przemysław Zagrajek ◽  
...  

Recently, one of the most commonly discussed applications of terahertz radiation is wireless telecommunication. It is believed that the future 6G systems will utilize this frequency range. Although the exact technology of future telecommunication systems is not yet known, it is certain that methods for increasing their bandwidth should be investigated in advance. In this paper, we present the diffractive optical elements for the frequency division multiplexing of terahertz waves. The structures have been designed as a combination of a binary phase grating and a converging diffractive lens. The grating allows for differentiating the frequencies, while the lens assures separation and focusing at the finite distance. Designed structures have been manufactured from polyamide PA12 using the SLS 3D printer and verified experimentally. Simulations and experimental results are shown for different focal lengths. Moreover, parallel data transmission is shown for two channels of different carrier frequencies propagating in the same optical path. The designed structure allowed for detecting both signals independently without observable crosstalk. The proposed diffractive elements can work in a wide range of terahertz and sub-terahertz frequencies, depending on the design assumptions. Therefore, they can be considered as an appealing solution, regardless of the band finally used by the future telecommunication systems.


2021 ◽  
pp. 1-27
Author(s):  
Tiberiu Dragu ◽  
Yonatan Lupu

Abstract How will advances in digital technology affect the future of human rights and authoritarian rule? Media figures, public intellectuals, and scholars have debated this relationship for decades, with some arguing that new technologies facilitate mobilization against the state and others countering that the same technologies allow authoritarians to strengthen their grip on power. We address this issue by analyzing the first game-theoretic model that accounts for the dual effects of technology within the strategic context of preventive repression. Our game-theoretical analysis suggests that technological developments may not be detrimental to authoritarian control and may, in fact, strengthen authoritarian control by facilitating a wide range of human rights abuses. We show that technological innovation leads to greater levels of abuses to prevent opposition groups from mobilizing and increases the likelihood that authoritarians will succeed in preventing such mobilization. These results have broad implications for the human rights regime, democratization efforts, and the interpretation of recent declines in violent human rights abuses.


2019 ◽  
Vol 53 (2) ◽  
pp. 108-118
Author(s):  
Martin Braschler ◽  
Linda Cappellato ◽  
Fabio Crestani ◽  
Nicola Ferro ◽  
Gundula Heinatz Bürki ◽  
...  

This is a report on the tenth edition of the Conference and Labs of the Evaluation Forum (CLEF 2019), held from September 9--12, 2019, in Lugano, Switzerland. CLEF was a four day event combining a Conference and an Evaluation Forum. The Conference featured keynotes by Bruce Croft, Yair Neuman, and Miguel Martínez, and presentation of peer reviewed research papers covering a wide range of topics in addition to many posters. The Evaluation Forum consisted to nine Labs: CENTRE, CheckThat, eHealth, eRisk, ImageCLEF, LifeCLEF, PAN, PIR-CLEF, and ProtestNews, addressing a wide range of tasks, media, languages, and ways to go beyond standard test collections. CLEF 2019 marked the 20th anniversary of CLEF, which was celebrated with a dedicated session and a book on the lessons learnt in twenty years of evaluation activities and the future perspectives for CLEF. CLEF 2019 also introduced the Industry Days to further extend the reach and impact of CLEF.


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