scholarly journals A core-brush 3D DNA nanostructure: the next generation of DNA nanomachine for ultrasensitive sensing and imaging of intracellular microRNA with rapid kinetics

2021 ◽  
Author(s):  
lingqi kong ◽  
Beibei Kou ◽  
Xiaolong Zhang ◽  
Ding Wang ◽  
Yali Yuan ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Next Generation ◽  
Dna Nanostructure ◽  
Rapid Kinetics ◽  
Highly Loaded ◽  
Dna Nanomachine

A highly loaded and integrated core-brush three-dimensional (3D) DNA nanostructure is constructed by programmatically assembling locked DNA walking arm (DA) and hairpin substrate (HS) into a repetitive array along the...

A dynamic 3D DNA nanostructure based on silicon-supported lipid bilayers: a highly efficient DNA nanomachine for rapid and sensitive sensing

2019 ◽  
Vol 55 (89) ◽  
pp. 13414-13417 ◽  
Author(s):  
Zhi-Bin Wen ◽  
Xin Peng ◽  
Ze-Zhou Yang ◽  
Ying Zhuo ◽  
Ya-Qin Chai ◽  
...  
Keyword(s):  
Lipid Bilayers ◽  
Three Dimensional ◽  
Dna Probes ◽  
Supported Lipid Bilayers ◽  
Dna Nanostructure ◽  
Highly Efficient ◽  
Self Powered ◽  
Lipid Interaction ◽  
Dna Nanomachine

Herein, we have developed a dynamic three-dimensional (3D) self-powered DNA nanomachine by anchoring cholesterol-labelled DNA probes to silicon-supported lipid bilayers via cholesterol–lipid interaction.

Highly Ordered and Field-Free 3D DNA Nanostructure: The Next Generation of DNA Nanomachine for Rapid Single-Step Sensing

2018 ◽  
Vol 140 (30) ◽  
pp. 9361-9364 ◽  
Author(s):  
Pu Zhang ◽  
Jie Jiang ◽  
Ruo Yuan ◽  
Ying Zhuo ◽  
Yaqin Chai
Keyword(s):  
Single Step ◽  
Next Generation ◽  
Dna Nanostructure ◽  
Dna Nanomachine

A simple, repeatable and highly stable self-powered solar-blind photoelectrochemical-type photodetector using amorphous Ga2O3 films grown on 3D carbon fiber paper

2021 ◽  
Author(s):  
Lijuan Huang ◽  
Zhengrui Hu ◽  
Hong Zhang ◽  
Yuanqiang Xiong ◽  
Shiqiang Fan ◽  
...  
Keyword(s):  
Carbon Fiber ◽  
Gallium Oxide ◽  
Three Dimensional ◽  
Next Generation ◽  
Solar Blind ◽  
Carbon Fiber Paper ◽  
Deep Ultraviolet ◽  
Self Powered ◽  
Ultraviolet Photodetectors

Gallium oxide (Ga2O3) has been extensively studied in recent years because it is a natural candidate material for next-generation solar-blind deep ultraviolet photodetectors (PDs). Herein, a three dimensional (3D) amorphous...

scholarly journals Optimization Design of a 2.5 Stage Highly Loaded Axial Compressor with a Bezier Surface Modeling Method

2020 ◽  
Vol 10 (11) ◽  
pp. 3860
Author(s):  
Song Huang ◽  
Jinxin Cheng ◽  
Chengwu Yang ◽  
Chuangxin Zhou ◽  
Shengfeng Zhao ◽  
...  
Keyword(s):  
Flow Field ◽  
Dimensional Space ◽  
Three Dimensional ◽  
Axial Compressor ◽  
High Dimensions ◽  
Peak Efficiency ◽  
Stall Margin ◽  
Second Stage ◽  
Highly Loaded ◽  
Three Dimensional Space

Due to the complexity of the internal flow field of compressors, the aerodynamic design and optimization of a highly loaded axial compressor with high performance still have three problems, which are rich engineering design experience, high dimensions, and time-consuming calculations. To overcome these three problems, this paper takes an engineering-designed 2.5-stage highly loaded axial flow compressor as an example to introduce the design process and the adopted design philosophies. Then, this paper verifies the numerical method of computational fluid dynamics. A new Bezier surface modeling method for the entire suction surface and pressure surface of blades is developed, and the multi-island genetic algorithm is directly used for further optimization. Only 32 optimization variables are used to optimize the rotors and stators of the compressor, which greatly overcome the problem of high dimensions, time-consuming calculations, and smooth blade surfaces. After optimization, compared with the original compressor, the peak efficiency is still improved by 0.12%, and the stall margin is increased by 2.69%. The increase in peak efficiency is mainly due to the rotors. Compared with the original compressor, for the second-stage rotor, the adiabatic efficiency is improved by about 0.4%, which is mainly due to the decreases of total pressure losses in the range of above 30% of the span height and 10%–30% of the chord length. Besides, for the original compressor, due to deterioration of the flow field near the tip region of the second-stage stator, the large low-speed region eventually evolves from corner separation into corner stall with three-dimensional space spiral backflow. For the optimized compressor, the main reason for the increased stall margin is that the flow field of the second-stage stator with a span height above 50% is improved, and the separation area and three-dimensional space spiral backflow are reduced.

scholarly journals Crystallization of a self-assembled three-dimensional DNA nanostructure

2013 ◽  
Vol 69 (2) ◽  
pp. 141-146 ◽  
Author(s):  
Kimberly N. Rendek ◽  
Raimund Fromme ◽  
Ingo Grotjohann ◽  
Petra Fromme
Keyword(s):  
Three Dimensional ◽  
Dna Nanostructure ◽  
Self Assembled

Study on Three-Dimensional Seismic Isolation System for Next Generation Nuclear Power Plant: Independent Cable Reinforced Rolling-Seal Air Spring

2004 ◽  
Author(s):  
Mitsuru Kageyama ◽  
Yoshihiko Hino ◽  
Satoshi Moro
Keyword(s):  
Power Plant ◽  
Nuclear Power ◽  
Seismic Isolation ◽  
Base Isolation ◽  
Three Dimensional ◽  
Outer Diameter ◽  
Next Generation ◽  
Air Spring ◽  
Isolation System ◽  
Rubber Sheet

In Japan, the development of the next generation NPP has been conducted in recent years. In the equipment/piping design of the plant, seismic condition has been required much more mitigate than before. So, the three-dimensional (abbreviation to 3D) seismic isolation system development has also been conducted since 2000. The superlative 3D base isolation system for the entire building was proposed. The system is composed of cable reinforced air springs, rocking arresters and viscous dampers. Dimensions of the air spring applied to the actual power plant are 8 meters in the outer-diameter and 3.5 meters in height. The allowable half strokes are 1.0 meters in horizontal and 0.5 meters in vertical respectively. The maximum supporting weight for a single device is 70 MN. The inner design air pressure is about 1.8MPa. This air spring has a distinguishing feature, which realizes 3D base isolation with a single device, whose natural periods are about 4 seconds in horizontal and about 3 seconds in vertical. In order to verify the 3D performance of this system, several feasibility tests were conducted. Firstly, 3D shaking table tests were conducted. The test specimen is scaled 1/4 of the actual device. The outer diameter and inner air pressure of air spring is 2 meters and 0.164 MPa. Next, a pressure resistant test for the sub cable, textile sheet and rubber sheet, which composed air spring, were conducted as a full scale model test. Then, air permeation test for the rubber sheet was also conducted. As a result, the proposed system was verified that it could be applied to the actual nuclear power plants.

Preclinical three-dimensional colorectal cancer model: The next generation of in vitro drug efficacy evaluation

2018 ◽  
Vol 234 (1) ◽  
pp. 181-191 ◽  
Author(s):  
Francesca Sensi ◽  
Edoardo D’Angelo ◽  
Sara D’Aronco ◽  
Roberto Molinaro ◽  
Marco Agostini
Keyword(s):  
Colorectal Cancer ◽  
Three Dimensional ◽  
Drug Efficacy ◽  
Next Generation ◽  
Cancer Model ◽  
Efficacy Evaluation

scholarly journals A Next-Generation Three-Dimensional Visualization Program VESTA 3

2012 ◽  
Vol 54 (2) ◽  
pp. 119-120
Author(s):  
Koichi MOMMA ◽  
Fujio IZUMI
Keyword(s):  
Three Dimensional ◽  
Next Generation
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