scholarly journals Systematic investigation of the aza-Cope reaction for fluorescence imaging of formaldehyde in vitro and in vivo

2021 ◽  
Author(s):  
Yimeng Du ◽  
Yuqing Zhang ◽  
Meirong Huang ◽  
Shushu Wang ◽  
Jianzheng Wang ◽  
...  

Systematic investigation of various homoallylamines reveals N-p-methoxybenzyl homoallylamine as the optimal 2-aza-Cope reaction moiety for development of highly efficient formaldehyde fluorescent probes for in vitro and in vivo imaging.

2020 ◽  
Vol 56 (56) ◽  
pp. 7718-7721 ◽  
Author(s):  
Linfang Wang ◽  
Jing Liu ◽  
Shengwei Zhao ◽  
Hongxing Zhang ◽  
Yuanqiang Sun ◽  
...  

Hydro-Si-oxazines were exploited as NIR fluorescent probes to monitor HClO/ONOO− produced by phagocytes in inflammation-related diseases.


2020 ◽  
Vol 39 (1) ◽  
pp. 209-221
Author(s):  
Jiafeng Wan ◽  
Xiaoyuan Zhang ◽  
Kai Zhang ◽  
Zhiqiang Su

Abstract In recent years, nanomaterials have attracted lots of attention from researchers due to their unique properties. Nanometer fluorescent materials, such as organic dyes, semiconductor quantum dots (QDs), metal nano-clusters (MNCs), carbon dots (CDs), etc., are widely used in biological imaging due to their high sensitivity, short response time, and excellent accuracy. Nanometer fluorescent probes can not only perform in vitro imaging of organisms but also achieve in vivo imaging. This provides medical staff with great convenience in cancer treatment. Combined with contemporary medical methods, faster and more effective treatment of cancer is achievable. This article explains the response mechanism of three-nanometer fluorescent probes: the principle of induced electron transfer (PET), the principle of fluorescence resonance energy transfer (FRET), and the principle of intramolecular charge transfer (ICT), showing the semiconductor QDs, precious MNCs, and CDs. The excellent performance of the three kinds of nano fluorescent materials in biological imaging is highlighted, and the application of these three kinds of nano fluorescent probes in targeted biological imaging is also introduced. Nanometer fluorescent materials will show their significance in the field of biomedicine.


2000 ◽  
Vol 57 (8) ◽  
pp. 1326-1333 ◽  
Author(s):  
I. Hellgren* ◽  
V. Drvota ◽  
R. Pieper ◽  
S. Enoksson ◽  
P. Blomberg ◽  
...  

2011 ◽  
Vol 10 (9) ◽  
pp. 890-890 ◽  
Author(s):  
Natalie Artzi ◽  
Nuria Oliva ◽  
Cristina Puron ◽  
Sagi Shitreet ◽  
Shay Artzi ◽  
...  

Biomaterials ◽  
2018 ◽  
Vol 159 ◽  
pp. 82-90 ◽  
Author(s):  
Feiyi Wang ◽  
Ge Xu ◽  
Xianfeng Gu ◽  
Zhijun Wang ◽  
Zhiqiang Wang ◽  
...  

2020 ◽  
Vol 7 (5) ◽  
pp. 1273-1283 ◽  
Author(s):  
Zhishan Xu ◽  
Yuliang Yang ◽  
Xianglei Jia ◽  
Lihua Guo ◽  
Xingxing Ge ◽  
...  

Iridium(iii)-based complexes with phosphine-imine (P^N) ligands are synthesized and authenticated. The combined treatment with Ir(iii) and BIX01294 potently inhibited tumour growth and lung metastasis in vitro and in vivo.


ACS Nano ◽  
2013 ◽  
Vol 7 (11) ◽  
pp. 9851-9859 ◽  
Author(s):  
Edakkattuparambil S. Shibu ◽  
Kenji Ono ◽  
Sakiko Sugino ◽  
Ayami Nishioka ◽  
Akikazu Yasuda ◽  
...  
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