scholarly journals A new PLA–Tween composited drug-carrying C60–Fe3O4 multifunctional ultrasound contrast agent based on three kinds of lesions

RSC Advances ◽  
2021 ◽  
Vol 11 (49) ◽  
pp. 31015-31029
Author(s):  
Baoqing Gao ◽  
Yao Feng ◽  
Xinmeng Chen ◽  
Jie Zhang
Keyword(s):  
Contrast Agent ◽  
Drug Carrier ◽  
Drug Loading ◽  
Ultrasound Contrast Agent ◽  
Agent Based ◽  
Ultrasound Contrast ◽  
Targeted Drug

A PLA–Tween composited drug-carrying C60–Fe3O4 microbubble was designed and prepared. Using Fe3O4 as a targeting factor and C60 as a drug carrier, C60–Fe3O4–WF, C60–Fe3O4–NET and C60–Fe3O4–DOX targeted drug-loading complexes were obtained.

scholarly journals Novel Span-PEG Multifunctional Ultrasound Contrast Agent Based on CNTs as a Magnetic Targeting Factor and a Drug Carrier

ACS Omega ◽  
2020 ◽  
Vol 5 (49) ◽  
pp. 31525-31534
Author(s):  
Jie Zhang ◽  
Zhongtao Liu ◽  
Shujing Zhou ◽  
Yang Teng ◽  
Xiangyu Zhang ◽  
...  
Keyword(s):  
Contrast Agent ◽  
Drug Carrier ◽  
Ultrasound Contrast Agent ◽  
Magnetic Targeting ◽  
Agent Based ◽  
Ultrasound Contrast

Lack of an Immune Response to Albunex®, a New Ultrasound Contrast Agent Based on Air-Filled Albumin Microspheres

1994 ◽  
Vol 104 (4) ◽  
pp. 372-378 ◽  
Author(s):  
Cathrine Christiansen ◽  
Anne Juelsrud Vebner ◽  
Berit Muan ◽  
Hogne Vik ◽  
Trond Haider ◽  
...  
Keyword(s):  
Immune Response ◽  
Contrast Agent ◽  
Ultrasound Contrast Agent ◽  
Agent Based ◽  
Albumin Microspheres ◽  
Ultrasound Contrast

Novel ultrasound contrast agent based on microbubbles generated from surfactant mixtures of Span 60 and polyoxyethylene 40 stearate

2010 ◽  
Vol 6 (9) ◽  
pp. 3542-3549 ◽  
Author(s):  
Zhanwen Xing ◽  
Hengte Ke ◽  
Jinrui Wang ◽  
Bo Zhao ◽  
Xiuli Yue ◽  
...  
Keyword(s):  
Contrast Agent ◽  
Ultrasound Contrast Agent ◽  
Surfactant Mixtures ◽  
Agent Based ◽  
Ultrasound Contrast ◽  
Span 60

scholarly journals New Polylactic Acid Multifunctional Ultrasound Contrast Agent Based on Graphene Oxide as the Carrier of Targeted Factor and Drug Delivery

ACS Omega ◽  
2019 ◽  
Vol 4 (3) ◽  
pp. 4691-4696
Author(s):  
Jie Zhang ◽  
Limei Song ◽  
Huiming Zhang ◽  
Shujing Zhou ◽  
Yufeng Jiao ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Graphene Oxide ◽  
Contrast Agent ◽  
Polylactic Acid ◽  
Ultrasound Contrast Agent ◽  
Agent Based ◽  
Ultrasound Contrast

A New Ultrasound Contrast Agent Based on Biodegradable Polymeric Microballoons

1991 ◽  
Vol 26 ◽  
pp. S190-S191 ◽  
Author(s):  
M. SCHNEIDER ◽  
P. BUSSAT ◽  
M. B. BARRAU ◽  
F. BODINO ◽  
C. GOTTI ◽  
...  
Keyword(s):  
Contrast Agent ◽  
Ultrasound Contrast Agent ◽  
Agent Based ◽  
Ultrasound Contrast

Preparation and In Vitro Evaluation of a Nano Ultrasound Contrast Agent Targeting Pancreatic Cancer

2021 ◽  
Vol 21 (3) ◽  
pp. 1413-1418
Author(s):  
Wu Chen ◽  
Xiaofang Liu ◽  
Yiying Li ◽  
Yongsheng Yang ◽  
Kun Xu ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Particle Size ◽  
Contrast Agent ◽  
Drug Loading ◽  
Ultrasound Contrast Agent ◽  
Ultrasound Contrast ◽  
Loading Efficiency ◽  
Targeted Ultrasound ◽  
Drug Loading Efficiency

To prepare a nano-sized ultrasound contrast agent that specifically targets pancreatic cancer cells and to evaluate its targeting effect In Vitro. PLGA-PEG-NHS was synthesized using PLGA, NHS, and PEG and detected using 1H-NMR. PLGA-PEG-NHS and PFOB were used to prepare PLGA nano contrast agent coated with PFOB by emulsification and volatilization, and then a hedgehog antibody was conjugated. The morphology of the nano contrast agent was observed using a transmission electron microscope, and its particle size and potential were measured using the dynamic light scattering method. The entrapment and drug loading efficiency of the nano contrast agent was measured using gas chromatography-mass spectrometry. The In Vitro release characteristics of the nano contrast agent was measured using the dialysis method. Human pancreatic cancer cell lines SW1990 and CFPAC1 were cultured in medium containing the nano contrast agent. The targeting ability of the nano contrast agent was qualitatively and quantitatively verified using fluorescence microscopy and flow cytometry. The average particle size of the targeted ultrasound contrast agent was 198.9 nm, zeta potential was −31.8 mv, entrapment rate was 63.7±3.9%, drug loading efficiency was 14.3±0.9%, and drug release was 85.3% in 48 h. In Vitro cell experiments showed that the targeted ultrasound contrast agent strongly bound to SW1990 cells with high expression of hedgehog antigen, but no specific binding was detected in CFPAC-1 cells which lack the hedgehog antigen. The nano ultrasound contrast agent prepared by emulsification and volatilization method can be potentially used for the diagnosis of pancreatic cancer.

Analysis of haemodynamic changes related to hepatic cirrhosis by an ultrasound contrast agent

2001 ◽  
Vol 120 (5) ◽  
pp. A2-A2
Author(s):  
G FELICIANGELI ◽  
G ARGALIA ◽  
L BOLOGNINI ◽  
T ABBATTISTA ◽  
M URBANI ◽  
...  
Keyword(s):  
Contrast Agent ◽  
Hepatic Cirrhosis ◽  
Ultrasound Contrast Agent ◽  
Ultrasound Contrast ◽  
Haemodynamic Changes
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