scholarly journals Multi-functional porous organic polymers for highly-efficient solid-phase extraction of β-agonists and β-blockers in milk

RSC Advances ◽  
2021 ◽  
Vol 11 (46) ◽  
pp. 28925-28933
Author(s):  
Ci Wu ◽  
Xingshuang Ning ◽  
Xi Chen ◽  
Junfeng Ma ◽  
Qun Zhao ◽  
...  
Keyword(s):  
Solid Phase Extraction ◽  
Phosphonic Acid ◽  
Solid Phase ◽  
Phase Extraction ◽  
Organic Polymers ◽  
Adsorption Efficiency ◽  
High Adsorption ◽  
Porous Organic Polymers ◽  
High Adsorption Capacity ◽  
Β Blockers

Novel phosphonic acid-functionalized porous organic polymers were synthesized through direct knitting method. It shows high adsorption efficiency and high adsorption capacity for multiple β-agonists and β-blockers analysis.

scholarly journals Isolation of Aflatoxin B1 from Moldy Foods by Solid-Phase Extraction Combined with Bifunctional Ionic Liquid-Based Silicas

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Luwei Fang ◽  
Minglei Tian ◽  
Xuemin Yan ◽  
Wei Xiao
Keyword(s):  
Ionic Liquid ◽  
Solid Phase Extraction ◽  
Aflatoxin B1 ◽  
Extraction Method ◽  
Solid Phase ◽  
Phase Extraction ◽  
Adsorption Efficiency ◽  
Imidazolium Chloride ◽  
Peanut Extract ◽  
Water Ratio

A solid-phase extraction method was developed by using new bifunctional ionic liquid-based silicas as sorbents to isolate aflatoxin B1 from moldy corn and peanut. Firstly, according to the adsorption efficiency, two sorbents imidazolium chloride-butylimidazolium chloride-based silica (Sil@BIm-Im) and imidazolium chloride-hexylimidazolium chloride-based silica (Sil@HIm-Im) were selected. The RSM was introduced to optimize adsorption conditions such as methanol/water ratio, time, and pH. Sil@HIm-Im, which had the highest adsorption efficiency, was used in SPE as a sorbent. After 2.0 mL of loading samples, washing solvents were optimized as 6.0 mL and 4.0 mL of water for corn and peanut, 2.0 mL of acetonitrile, and 3.0 mL of methanol. 3.0 mL of methanol/acetic acid (2.0% vol.) was investigated as an elution solvent. Finally, 0.009 μg/g and 0.023 μg/g of aflatoxin B1 were obtained in corn and peanut extract with recoveries of 80.0%–103.3% and RSDs of 2.37%–6.58%.

Environmental chiral analysis of β-blockers: evaluation of different n-alkyl-modified SBA-15 mesoporous silicas as sorbents in solid-phase extraction

2018 ◽  
Vol 15 (6) ◽  
pp. 362 ◽  
Author(s):  
Mariana Silva ◽  
Sonia Morante-Zarcero ◽  
Damián Pérez-Quintanilla ◽  
María Luisa Marina ◽  
Isabel Sierra
Keyword(s):  
Electron Microscopy ◽  
Risk Assessment ◽  
Mesoporous Silica ◽  
Solid Phase Extraction ◽  
Water Samples ◽  
Solid Phase ◽  
Sewage Water ◽  
Chiral Analysis ◽  
Phase Extraction ◽  
Β Blockers

Environmental contextβ-Blockers are important chiral pharmaceuticals found as micropollutants in environmental waters as a result of incomplete removal during wastewater treatment. Because they display enantioselective toxicity, it is necessary to include chiral information in an environmental risk assessment. We have developed an analytical method using mesoporous silica for extracting β-blockers in water samples before their specific chiral analysis. AbstractThe extraction and preconcentration of chiral β-blockers in environmental water was evaluated by solid-phase extraction (SPE) employing an SBA-15 ordered mesoporous silica functionalised with alkyl chains of different length. The materials were characterised by X-ray diffraction, transmission electron microscopy, scanning electron microscopy, nitrogen adsorption–desorption isotherm measurements and elemental analysis. Important parameters influencing extraction efficiency, including the type and amount of sorbent and the breakthrough volume, were optimised. The results obtained showed that the organic chain length played an important role in the behaviour of these sorbents. Under optimised conditions, using 200 mg SBA-15-C8 as sorbent, a simple analytical method based on off-line SPE coupled to chiral capillary electrophoresis with diode array detection (SPE-chiral CE-DAD) was developed. Method detection and quantification limits were lower than 0.6 and 1.9 µg L −1 respectively for all enantiomers, with a preconcentration factor of 500-fold. The method was successfully applied to the chiral analysis of atenolol, metoprolol, pindolol and propranolol in river and sewage water samples. Satisfactory recoveries (between 86 ± 2 and 98 ± 1 %) and repeatability (relative standard deviation (RSD) < 9 %, n = 3) were obtained. Metoprolol was detected in sewage water at a concentration of 10.7 and 9.9 µg L−1 and an enantiomeric fraction of 0.52 and 0.48 for the first- and the second-migrating enantiomers respectively. These results emphasise the importance of enantioselective analysis for environmental risk assessment.

Retention and selectivity of basic drugs on solid-phase extraction sorbents: Application to direct determination of β-blockers in urine

2014 ◽  
Vol 406 (17) ◽  
pp. 4207-4215 ◽  
Author(s):  
Warunya Boonjob ◽  
Hana Sklenářová ◽  
Francisco J. Lara ◽  
Ana M. García-Campaña ◽  
Petr Solich
Keyword(s):  
Solid Phase Extraction ◽  
Solid Phase ◽  
Direct Determination ◽  
Phase Extraction ◽  
Basic Drugs ◽  
Β Blockers
Sign in / Sign up

Export Citation Format

Share Document