2-Thiazolines: An update on synthetic methods and catalysis

2021 ◽  
Author(s):  
Joel Ivan Badillo Gómez ◽  
Maryse Gouygou ◽  
Jose G. López-Cortés ◽  
M. Carmen Ortega-Alfaro
Keyword(s):  
Organic Synthesis ◽  
Building Block ◽  
Synthetic Methods ◽  
Important Building Block

2-Thiazoline is an important building block in organic synthesis and still having great importance in many areas of chemistry. At the end of the last century, the use of 2-thiazolines...

UV-Light-Induced Dehydrogenative N-Acylation of Amines with 2-Nitrobenzaldehydes to Give 2-Aminobenzamides

Synthesis ◽  
2022 ◽  
Author(s):  
Dishu Zeng ◽  
Tianbao Yang ◽  
Niu Tang ◽  
Wei Deng ◽  
Jiannan Xiang ◽  
...  
Keyword(s):  
Amino Acid ◽  
Organic Synthesis ◽  
Efficient Method ◽  
Building Block ◽  
Room Temperature ◽  
Uv Light ◽  
Amino Acid Derivatives ◽  
One Pot ◽  
Plausible Mechanism ◽  
High Yields

A simple, mild, green and efficient method for the synthesis of 2-aminobenzamides was highly desired in organic synthesis. Herein, we developed an efficient, one-pot strategy for the synthesis of 2-aminobenzamides with high yields irradiated by UV light. 32 examples proceeded successfully by this photo-induced protocol. The yield reached up to 92%. The gram scale was also achieved easily. This building block could be applied in the preparation of quinazolinones derivatives. Amino acid derivatives could be employed smoothly at room temperature. Finally, a plausible mechanism was proposed.

Sēra dioksīda fizikāli ķīmisko īpašību pielietojums jaunu organiskās sintēzes metožu izstrādē / Development of New Organic Synthesis Methods Based on Physico-Chemical Properties of Sulfur Dioxide

2021 ◽  
Author(s):  
◽  
Krista Gulbe
Keyword(s):  
Organic Synthesis ◽  
Chemical Properties ◽  
Coupling Reaction ◽  
Synthetic Methods ◽  
Synthesis Methods ◽  
Chemical Transformations ◽  
Scientific Publications ◽  
Cross Coupling Reaction ◽  
Aryl Acetylenes ◽  
The Republic

The Doctoral Thesis has been prepared as a collection of thematically related scientific publications comprising five publications in the SCI journals, one patent of the Republic of Latvia, and one application for patent of the Republic of Latvia. We have carried out fundamental research on the applications of SO2 as a solvent and reagent in organic synthesis. We have developed several novel synthetic methods that represent the use of liquid SO2 as a solvent for chemical transformations that proceed via carbenium ion intermediates: a) hydration of aryl acetylenes; b) hydrohalogenation of aryl acetylenes; c) ring opening of methylenecyclopropanes with halides; d) glycosylation with glycosyl fluorides. By employing DABSO as an SO2 surrogate, we have also discovered the catalytic activity of Ru(II) complexes towards sulfonylative cross coupling reaction. This finding has been applied for the synthesis of sulfonyl derived compounds.

Grief and Healing Trajectories of Drug-Death-Bereaved Parents

2018 ◽  
Vol 80 (4) ◽  
pp. 629-647 ◽  
Author(s):  
William Feigelman ◽  
Beverly Feigelman ◽  
Lillian M. Range
Keyword(s):  
Posttraumatic Growth ◽  
Emotional Distress ◽  
Building Block ◽  
Qualitative Interviews ◽  
Medical Personnel ◽  
Significant Others ◽  
Bereaved Parents ◽  
Financial Burdens ◽  
Drug Death ◽  
Important Building Block

We explored parents’ views of the trajectories of their adult children’s eventual deaths from drugs with in-depth qualitative interviews from 11 bereaved parents. Parents reported great emotional distress and high financial burdens as their children went through death spirals of increasing drug involvements. These deaths often entailed anxiety-inducing interactions with police or medical personnel, subsequent difficulties with sharing death cause information with socially significant others, and longer term problems from routine interactions. Eventually, though, many of these longer term bereaved parents reported overcoming these obstacles and developing posttraumatic growth. Openly disclosing the nature of the death seemed to be an important building block for their healing.

Synthesis of a Polysiloxane with High Reaction Activity

2014 ◽  
Vol 998-999 ◽  
pp. 15-18
Author(s):  
Сhao Hong Dong ◽  
Zhou Lu ◽  
Ping Zhu ◽  
Lei Wang
Keyword(s):  
Organic Synthesis ◽  
Methyl Iodide ◽  
Building Block ◽  
Nmr Spectra ◽  
Catalytic Amount ◽  
Reaction Conditions ◽  
Ir And Nmr Spectra ◽  
High Reaction ◽  
Ft Ir

A novel building block in organic synthesis, poly (4-iodobutoxylmethylsiloxane)(PIBMS) with high reaction activity was prepared by poly (hydromethylsiloxane)(PHMS), methyl iodide and tetrahydrofuran (THF) in the presence of a catalytic amount of PdCl2. The structure of PIBMS was characterized by the FT-IR and NMR spectra. The reaction conditions were optimized.

In vitro reconstitution of the biosynthetic pathway of 3-hydroxypicolinic acid

2019 ◽  
Vol 17 (3) ◽  
pp. 454-460 ◽  
Author(s):  
Xuan Yun ◽  
Qian Zhang ◽  
Meinan Lv ◽  
Hai Deng ◽  
Zixin Deng ◽  
...  
Keyword(s):  
Natural Products ◽  
Building Block ◽  
Biosynthetic Pathway ◽  
In Vitro Reconstitution ◽  
Important Building Block

Four enzymes direct the biosynthesis of 3-hydroxypicolinic acid, an important building block of bacterial natural products.

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