Digital SERS sensing platform using 3D nanolaminate plasmonic crystals coupled with Au nanoparticles for accurate quantitative detection of dopamine

Nanoscale ◽  
2021 ◽  
Author(s):  
WONIL NAM ◽  
Wansun Kim ◽  
Wei Zhou ◽  
Eun-Ah You
Keyword(s):  
Raman Spectroscopy ◽  
Signal Analysis ◽  
Au Nanoparticles ◽  
Surface Enhanced Raman Spectroscopy ◽  
Quantitative Detection ◽  
Plasmonic Crystals ◽  
Sensing Platform ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Sers Sensing

We report a digital surface-enhanced Raman spectroscopy (SERS) sensing platform using the arrays of 3D nanolaminate plasmonic crystals (NLPC) coupled with Au nanoparticles and the digital (on/off) SERS signal analysis...

Multivariate Analysis Aided Surface-Enhanced Raman Spectroscopy (MVA-SERS) Multiplex Quantitative Detection of Trace Fentanyl in Illicit Drug Mixtures Using a Handheld Raman Spectrometer

2021 ◽  
pp. 000370282110329
Author(s):  
Ling Wang ◽  
Mario O. Vendrell-Dones ◽  
Chiara Deriu ◽  
Sevde Doğruer ◽  
Peter de B. Harrington ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Principal Component ◽  
Surface Enhanced Raman Spectroscopy ◽  
Quantitative Detection ◽  
Least Squares Regression ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Sers Detection ◽  
Current Screening

Recently there has been upsurge in reports that illicit seizures of cocaine and heroin have been adulterated with fentanyl. Surface-enhanced Raman spectroscopy (SERS) provides a useful alternative to current screening procedures that permits detection of trace levels of fentanyl in mixtures. Samples are solubilized and allowed to interact with aggregated colloidal nanostars to produce a rapid and sensitive assay. In this study, we present the quantitative determination of fentanyl in heroin and cocaine using SERS, using a point-and-shoot handheld Raman system. Our protocol is optimized to detect pure fentanyl down to 0.20 ± 0.06 ng/mL and can also distinguish pure cocaine and heroin at ng/mL levels. Multiplex analysis of mixtures is enabled by combining SERS detection with principal component analysis and super partial least squares regression discriminate analysis (SPLS-DA), which allow for the determination of fentanyl as low as 0.05% in simulated seized heroin and 0.10% in simulated seized cocaine samples.

scholarly journals Refractive index sensing and surface-enhanced Raman spectroscopy using silver–gold layered bimetallic plasmonic crystals

2017 ◽  
Vol 8 ◽  
pp. 2492-2503 ◽  
Author(s):  
Somi Kang ◽  
Sean E Lehman ◽  
Matthew V Schulmerich ◽  
An-Phong Le ◽  
Tae-woo Lee ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Refractive Index ◽  
Electric Fields ◽  
Surface Enhanced Raman Spectroscopy ◽  
Plasmonic Crystals ◽  
Metal Thickness ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Difference Time

Herein we describe the fabrication and characterization of Ag and Au bimetallic plasmonic crystals as a system that exhibits improved capabilities for quantitative, bulk refractive index (RI) sensing and surface-enhanced Raman spectroscopy (SERS) as compared to monometallic plasmonic crystals of similar form. The sensing optics, which are bimetallic plasmonic crystals consisting of sequential nanoscale layers of Ag coated by Au, are chemically stable and useful for quantitative, multispectral, refractive index and spectroscopic chemical sensing. Compared to previously reported homometallic devices, the results presented herein illustrate improvements in performance that stem from the distinctive plasmonic features and strong localized electric fields produced by the Ag and Au layers, which are optimized in terms of metal thickness and geometric features. Finite-difference time-domain (FDTD) simulations theoretically verify the nature of the multimode plasmonic resonances generated by the devices and allow for a better understanding of the enhancements in multispectral refractive index and SERS-based sensing. Taken together, these results demonstrate a robust and potentially useful new platform for chemical/spectroscopic sensing.

scholarly journals Dual-triggered nanoaggregates of cucurbit[7]uril and gold nanoparticles for multi-spectroscopic quantification of creatinine in urinalysis

2020 ◽  
Vol 8 (21) ◽  
pp. 7051-7058
Author(s):  
Weng-I Katherine Chio ◽  
Suresh Moorthy ◽  
Jayakumar Perumal ◽  
Dinish U. S. ◽  
Ivan P. Parkin ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Raman Spectroscopy ◽  
Surface Enhanced Raman Spectroscopy ◽  
Quantitative Detection ◽  
Vis Spectroscopy ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

A novel nanosensing platform was developed for the quantitative detection of creatinine of clinically relevant concentrations via UV-Vis spectroscopy and surface-enhanced Raman spectroscopy.

scholarly journals Electric field induced surface-enhanced Raman spectroscopy for multianalyte detection

2015 ◽  
Vol 17 (11) ◽  
pp. 7095-7099 ◽  
Author(s):  
Sumeet Walia ◽  
Aditya K. Shah ◽  
Paul R. Stoddart ◽  
Madhu Bhaskaran ◽  
Sharath Sriram
Keyword(s):  
Raman Spectroscopy ◽  
Electric Field ◽  
Surface Enhanced Raman Spectroscopy ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Multianalyte Detection ◽  
Sers Sensing

This work demonstrates the ability to detect and isolate an analyte from a multianalyte mixture by SERS sensing.

Morphological evolution of gold nanoparticles on silicon nanowires and their plasmonics

RSC Advances ◽  
2015 ◽  
Vol 5 (61) ◽  
pp. 49708-49718 ◽  
Author(s):  
Yuan Li ◽  
Wenwu Shi ◽  
Aditya Gupta ◽  
Nitin Chopra
Keyword(s):  
Gold Nanoparticles ◽  
Raman Spectroscopy ◽  
Silicon Nanowires ◽  
Au Nanoparticles ◽  
Morphological Evolution ◽  
Surface Enhanced Raman Spectroscopy ◽  
Si Nanowires ◽  
One Dimensional ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

One-dimensional heterostructures composed of silicon (Si) nanowires and uniformly decorated with gold (Au) nanoparticles were fabricated and used as a substrate for organic detection based on the surface-enhanced Raman spectroscopy.

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