scholarly journals Dual-triggered nanoaggregates of cucurbit[7]uril and gold nanoparticles for multi-spectroscopic quantification of creatinine in urinalysis

2020 ◽  
Vol 8 (21) ◽  
pp. 7051-7058
Author(s):  
Weng-I Katherine Chio ◽  
Suresh Moorthy ◽  
Jayakumar Perumal ◽  
Dinish U. S. ◽  
Ivan P. Parkin ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Raman Spectroscopy ◽  
Surface Enhanced Raman Spectroscopy ◽  
Quantitative Detection ◽  
Vis Spectroscopy ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

A novel nanosensing platform was developed for the quantitative detection of creatinine of clinically relevant concentrations via UV-Vis spectroscopy and surface-enhanced Raman spectroscopy.

Multivariate Analysis Aided Surface-Enhanced Raman Spectroscopy (MVA-SERS) Multiplex Quantitative Detection of Trace Fentanyl in Illicit Drug Mixtures Using a Handheld Raman Spectrometer

2021 ◽  
pp. 000370282110329
Author(s):  
Ling Wang ◽  
Mario O. Vendrell-Dones ◽  
Chiara Deriu ◽  
Sevde Doğruer ◽  
Peter de B. Harrington ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Principal Component ◽  
Surface Enhanced Raman Spectroscopy ◽  
Quantitative Detection ◽  
Least Squares Regression ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Sers Detection ◽  
Current Screening

Recently there has been upsurge in reports that illicit seizures of cocaine and heroin have been adulterated with fentanyl. Surface-enhanced Raman spectroscopy (SERS) provides a useful alternative to current screening procedures that permits detection of trace levels of fentanyl in mixtures. Samples are solubilized and allowed to interact with aggregated colloidal nanostars to produce a rapid and sensitive assay. In this study, we present the quantitative determination of fentanyl in heroin and cocaine using SERS, using a point-and-shoot handheld Raman system. Our protocol is optimized to detect pure fentanyl down to 0.20 ± 0.06 ng/mL and can also distinguish pure cocaine and heroin at ng/mL levels. Multiplex analysis of mixtures is enabled by combining SERS detection with principal component analysis and super partial least squares regression discriminate analysis (SPLS-DA), which allow for the determination of fentanyl as low as 0.05% in simulated seized heroin and 0.10% in simulated seized cocaine samples.

scholarly journals Detection of Triphenylmethane Drugs in Fish Muscle by Surface-Enhanced Raman Spectroscopy Coupled with Au-Ag Core-Shell Nanoparticles

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Lu Pei ◽  
Yiqun Huang ◽  
Chunying Li ◽  
Yuanyuan Zhang ◽  
Barbara A. Rasco ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Malachite Green ◽  
Crystal Violet ◽  
Bimetallic Nanoparticles ◽  
Limit Of Detection ◽  
Fish Muscle ◽  
Surface Enhanced Raman Spectroscopy ◽  
Vis Spectroscopy ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

Silver-coated gold bimetallic nanoparticles were synthesized and used as substrates for surface-enhanced Raman spectroscopy (SERS) in detecting prohibited triphenylmethane drugs (including crystal violet and malachite green) in fish muscle. The optical properties and physical properties of bimetallic nanospheres were characterized by UV-Vis spectroscopy and transmission electron microscopy. The optimal nanospheres selected had relatively uniform size (diameter: 33 ± 3 nm) with a silver layer coated on the surface of gold seed (diameter: 18 ± 2 nm). For both crystal violet and malachite green, characteristic SERS spectral features could be identified at concentration as low as 0.1 μg/L with these bimetallic nanospheres. Crystal violet and malachite green residues in fish muscle could also be detected at levels as low as 0.1 ng/g, which could meet the most restricted regulatory requirements for the limit of detection in terms of analytical methods for crystal violet or malachite green in fish muscle. This study provides a basis for applying SERS technology with bimetallic nanoparticles to the identification of trace amounts of prohibited substances in aquatic food products, and the methodology could be extended to analyses of other hazardous chemicals in complex food matrices like vegetables and meats.

Mapping gold nanoparticles on and in edible leaves in situ using surface enhanced Raman spectroscopy

RSC Advances ◽  
2016 ◽  
Vol 6 (65) ◽  
pp. 60152-60159 ◽  
Author(s):  
Zhiyun Zhang ◽  
Huiyuan Guo ◽  
Yingqing Deng ◽  
Baoshan Xing ◽  
Lili He
Keyword(s):  
Gold Nanoparticles ◽  
Raman Spectroscopy ◽  
Surface Enhanced Raman Spectroscopy ◽  
Mapping Technique ◽  
Raman Spectroscopic ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Spinach Leaves

A surface enhanced Raman spectroscopic (SERS) mapping technique was applied to qualitatively detect and characterize gold nanoparticles on and in spinach leaves in situ.

An ultrasensitive “turn-off” SERS sensor for quantitatively detecting heparin based on 4-mercaptobenzoic acid functionalized gold nanoparticles

2017 ◽  
Vol 9 (17) ◽  
pp. 2517-2522 ◽  
Author(s):  
Chenmeng Zhang ◽  
Xiu Liang ◽  
Tingting You ◽  
Nan Yang ◽  
Yukun Gao ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Raman Spectroscopy ◽  
Surface Enhanced Raman Spectroscopy ◽  
Functionalized Gold Nanoparticles ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

We develop an ultrasensitive “turn off” Surface Enhanced Raman Spectroscopy (SERS) sensor for the detection of heparin based on the anti-aggregation of 4-mercaptobenzoic acid stabilized gold nanoparticles.

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