Near-Infrared Emitting Dual-Stimuli-Responsive Carbon Dots from Endogenous Bile Pigments

Nanoscale ◽  
2021 ◽  
Author(s):  
Parinaz Fathi ◽  
Parikshit Moitra ◽  
Madeleine M. McDonald ◽  
Mandy Brigitte Esch ◽  
Dipanjan Pan
Keyword(s):  
Surface Modification ◽  
Carbon Dots ◽  
Biomedical Applications ◽  
Near Infrared ◽  
Bile Pigments ◽  
Careful Selection ◽  
Stimuli Responsive ◽  
Carbon Dot ◽  
Surface Modification Techniques ◽  
Selection Of

Carbon dots are biocompatible nanoparticles suitable for a variety of biomedical applications. Careful selection of carbon dot precursors and surface modification techniques has allowed for the development of carbon dots...

scholarly journals Topographical and Biomechanical Guidance of Electrospun Fibers for Biomedical Applications

Polymers ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 2896
Author(s):  
Sara Ferraris ◽  
Silvia Spriano ◽  
Alessandro Calogero Scalia ◽  
Andrea Cochis ◽  
Lia Rimondini ◽  
...  
Keyword(s):  
Surface Modification ◽  
Biomedical Applications ◽  
Biomedical Application ◽  
Electrospun Fibers ◽  
Natural Polymers ◽  
Polymeric Fibers ◽  
Biological Phenomena ◽  
Proper Design ◽  
Synthetic And Natural Polymers ◽  
Selection Of

Electrospinning is gaining increasing interest in the biomedical field as an eco-friendly and economic technique for production of random and oriented polymeric fibers. The aim of this review was to give an overview of electrospinning potentialities in the production of fibers for biomedical applications with a focus on the possibility to combine biomechanical and topographical stimuli. In fact, selection of the polymer and the eventual surface modification of the fibers allow selection of the proper chemical/biological signal to be administered to the cells. Moreover, a proper design of fiber orientation, dimension, and topography can give the opportunity to drive cell growth also from a spatial standpoint. At this purpose, the review contains a first introduction on potentialities of electrospinning for the obtainment of random and oriented fibers both with synthetic and natural polymers. The biological phenomena which can be guided and promoted by fibers composition and topography are in depth investigated and discussed in the second section of the paper. Finally, the recent strategies developed in the scientific community for the realization of electrospun fibers and for their surface modification for biomedical application are presented and discussed in the last section.

scholarly journals 3D-printable zwitterionic nano-composite hydrogel system for biomedical applications

2020 ◽  
Vol 11 ◽  
pp. 204173142096729
Author(s):  
Nathalie Sällström ◽  
Andrew Capel ◽  
Mark P Lewis ◽  
Daniel S Engstrøm ◽  
Simon Martin
Keyword(s):  
Mechanical Properties ◽  
Biomedical Applications ◽  
Culture Medium ◽  
Careful Selection ◽  
Nano Composite ◽  
Significant Difference ◽  
Nano Clay ◽  
Hydrogel Surface ◽  
Selection Of ◽  
Hydrogel System

Herein, the cytotoxicity of a novel zwitterionic sulfobetaine hydrogel system with a nano-clay crosslinker has been investigated. We demonstrate that careful selection of the composition of the system (monomer to Laponite content) allows the material to be formed into controlled shapes using an extrusion based additive manufacturing technique with the ability to tune the mechanical properties of the product. Moreover, the printed structures can support their own weight without requiring curing during printing which enables the use of a printing-then-curing approach. Cell culture experiments were conducted to evaluate the neural cytotoxicity of the developed hydrogel system. Cytotoxicity evaluations were conducted on three different conditions; a control condition, an indirect condition (where the culture medium used had been in contact with the hydrogel to investigate leaching) and a direct condition (cells growing directly on the hydrogel). The result showed no significant difference in cell viability between the different conditions and cells were also found to be growing on the hydrogel surface with extended neurites present.

Carbon dots with red/near-infrared emissions and their intrinsic merits for biomedical applications

Carbon ◽  
2020 ◽  
Vol 167 ◽  
pp. 322-344 ◽  
Author(s):  
Hui Ding ◽  
Xuan-Xuan Zhou ◽  
Ji-Shi Wei ◽  
Xiao-Bing Li ◽  
Bo-Tao Qin ◽  
...  
Keyword(s):  
Carbon Dots ◽  
Biomedical Applications ◽  
Near Infrared ◽  
Infrared Emissions

scholarly journals Nanoscale Carbon-Polymer Dots for Theranostics and Biomedical Exploration

2021 ◽  
Vol 2 (3) ◽  
pp. 118-130
Author(s):  
Shazid Md. Sharker ◽  
Minjae Do
Keyword(s):  
Single Particle ◽  
Carbon Dots ◽  
Biomedical Applications ◽  
Surface Passivation ◽  
Therapeutic Applications ◽  
Nir Light ◽  
Polymer Dots ◽  
Uv Visible ◽  
And Control ◽  
Selection Of

In recent years, new carbonized nanomaterials have emerged in imaging, sensing, and various biomedical applications. Published literature shows that carbon dots (CDs) have been explored more extensively than any other nanomaterials. However, its polymeric version, carbon polymer dots (CPDs), did not get much attention. The non-conjugated and single-particle CPDs have all the merits of polymer and CDs, such as photoluminescent properties. The partially carbonized CPDs can be applied like CDs without surface passivation and functionalization. This merit can be further enhanced through the selection of desired precursors and control of carbonization synthesis. CPDs can absorb UV-visible-NIR light and can enhance the photoresponsive chemical and biochemical interactions. This review aims to introduce this area of renewed interest and provide insights into current developments of CPDs nanoparticles and present an overview of chemical, biological, and therapeutic applications.

Enzymatically synthesised MnO2 nanoparticles for efficient near-infrared photothermal therapy and dual-responsive magnetic resonance imaging

Nanoscale ◽  
2021 ◽  
Author(s):  
Jin Liu ◽  
Liandong Feng ◽  
Yuzhou Wu
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Biomedical Applications ◽  
Near Infrared ◽  
Tumour Microenvironment ◽  
Stimuli Responsive ◽  
Resonance Imaging ◽  
Dual Responsive ◽  
Mno2 Nanoparticles ◽  
Magnetic Resonance Imaging Mri

Manganese dioxide (MnO2) nanoparticles (NPs) are highly attractive for biomedical applications due to their biocompatibility, stimuli-responsive magnetic resonance imaging (MRI) properties and capability to modulate the hypoxic tumour microenvironment (TME)....

scholarly journals Innovative Surface Modification Procedures to Achieve Micro/Nano-Graded Ti-Based Biomedical Alloys and Implants

Coatings ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 647
Author(s):  
Jie Li ◽  
Peng Zhou ◽  
Shokouh Attarilar ◽  
Hongyuan Shi
Keyword(s):  
Surface Modification ◽  
Biomedical Applications ◽  
Review Paper ◽  
Titanium Implant ◽  
Surface Characteristics ◽  
Multi Scale ◽  
Treatment Techniques ◽  
Bactericidal Effects ◽  
Surface Modification Techniques ◽  
Dimensional Printing

Due to the growing aging population of the world, and as a result of the increasing need for dental implants and prostheses, the use of titanium and its alloys as implant materials has spread rapidly. Although titanium and its alloys are considered the best metallic materials for biomedical applications, the need for innovative technologies is necessary due to the sensitivity of medical applications and to eliminate any potentially harmful reactions, enhancing the implant-to-bone integration and preventing infection. In this regard, the implant’s surface as the substrate for any reaction is of crucial importance, and it is accurately addressed in this review paper. For constructing this review paper, an internet search was performed on the web of science with these keywords: surface modification techniques, titanium implant, biomedical applications, surface functionalization, etc. Numerous recent papers about titanium and its alloys were selected and reviewed, except for the section on forthcoming modern implants, in which extended research was performed. This review paper aimed to briefly introduce the necessary surface characteristics for biomedical applications and the numerous surface treatment techniques. Specific emphasis was given to micro/nano-structured topographies, biocompatibility, osteogenesis, and bactericidal effects. Additionally, gradient, multi-scale, and hierarchical surfaces with multifunctional properties were discussed. Finally, special attention was paid to modern implants and forthcoming surface modification strategies such as four-dimensional printing, metamaterials, and metasurfaces. This review paper, including traditional and novel surface modification strategies, will pave the way toward designing the next generation of more efficient implants.

Sign in / Sign up

Export Citation Format

Share Document