Development of carrier-free nanodrugs based on low molecular heparin-doxorubicin conjugate assembly with smart pH-triggered drug release characteristics for combinatorial antitumor therapy

2021 ◽  
Author(s):  
Bo Fan ◽  
Qian Li ◽  
Yanping Jiang ◽  
Weiguang Shen ◽  
Yang Xing ◽  
...  
Keyword(s):  
Drug Release ◽  
Solid Tumors ◽  
Single Treatment ◽  
Antitumor Therapy ◽  
Carrier Free ◽  
Triggered Drug Release

Abnormal angiogenesis is a hallmark of solid tumors. The combination of cytotoxic and anti-angiogenic drugs has been proved to be more effective than single treatment. As a shining platform, the...

Low intensity focused ultrasound (LIFU) triggered drug release from cetuximab-conjugated phase-changeable nanoparticles for precision theranostics against anaplastic thyroid carcinoma

2019 ◽  
Vol 7 (1) ◽  
pp. 196-210 ◽  
Author(s):  
Yang Wang ◽  
Guoqing Sui ◽  
Dengke Teng ◽  
Qimeihui Wang ◽  
Jia Qu ◽  
...  
Keyword(s):  
Molecular Imaging ◽  
Drug Release ◽  
Thyroid Carcinoma ◽  
Focused Ultrasound ◽  
Anaplastic Thyroid Carcinoma ◽  
Antitumor Therapy ◽  
Low Intensity ◽  
Targeted Ultrasound ◽  
Triggered Drug Release ◽  
Ultrasound Molecular Imaging

This study provides an efficient theranostic strategy for concurrent targeted ultrasound molecular imaging and effective synergistic antitumor therapy.

scholarly journals Tumor-triggered drug release from calcium carbonate-encapsulated gold nanostars for near-infrared photodynamic/photothermal combination antitumor therapy

Theranostics ◽  
2017 ◽  
Vol 7 (6) ◽  
pp. 1650-1662 ◽  
Author(s):  
Yanlei Liu ◽  
Xiao Zhi ◽  
Meng Yang ◽  
Jingpu Zhang ◽  
Lingnan Lin ◽  
...  
Keyword(s):  
Calcium Carbonate ◽  
Drug Release ◽  
Near Infrared ◽  
Antitumor Therapy ◽  
Gold Nanostars ◽  
Triggered Drug Release

Facile synthesis of organosilica-capped mesoporous silica nanocarriers with selective redox-triggered drug release properties for safe tumor chemotherapy

2019 ◽  
Vol 7 (5) ◽  
pp. 1825-1832 ◽  
Author(s):  
Luying Shen ◽  
Shan Pan ◽  
Dechao Niu ◽  
Jianping He ◽  
Xiaobo Jia ◽  
...  
Keyword(s):  
Drug Release ◽  
Mesoporous Silica ◽  
Facile Synthesis ◽  
Triggered Drug Release ◽  
Facile Route

We develop a facile route to synthesize organosilica-capped mesoporous silica nanocarriers for efficient and safe redox-triggered tumor chemotherapy.

scholarly journals pH-triggered degradation and release of doxorubicin from zeolitic imidazolate framework-8 (ZIF8) decorated with polyacrylic acid

RSC Advances ◽  
2021 ◽  
Vol 11 (16) ◽  
pp. 9222-9234
Author(s):  
Vy Anh Tran ◽  
Sang-Wha Lee
Keyword(s):  
Drug Release ◽  
Polyacrylic Acid ◽  
Acidic Ph ◽  
Zeolitic Imidazolate Framework ◽  
Triggered Drug Release

The ZIF8–Dox@PAA nanocarrier demonstrated pH-triggered drug release through the detachment of the PAA layer along with the destruction of ZIF8 framework in acidic pH environment.

PEG–PEI-modified gated N-doped mesoporous carbon nanospheres for pH/NIR light-triggered drug release and cancer phototherapy

2021 ◽  
Author(s):  
Snigdharani Panda ◽  
Chandra Sekhar Bhol ◽  
Sujit Kumar Bhutia ◽  
Sasmita Mohapatra
Keyword(s):  
Drug Release ◽  
Mesoporous Carbon ◽  
Laser Excitation ◽  
Outer Shell ◽  
Carbon Nanospheres ◽  
Nir Light ◽  
Triggered Drug Release ◽  
Hybrid Nanoparticle

A hybrid nanoparticle consisting of N-doped mesoporous carbon nanospheres as core and thermosensitive PEG–PEI as outer shell shows multiple therapeutic actions such as PTT, PDT and NIR sensitive drug release under single 980 nm laser excitation.

Imaging Laser-Triggered Drug Release from Gold Nanocages with Transient Absorption Lifetime Microscopy

2017 ◽  
Vol 9 (23) ◽  
pp. 19653-19661 ◽  
Author(s):  
Yongkui Xu ◽  
Qi Liu ◽  
Ruoyu He ◽  
Xianchong Miao ◽  
Minbiao Ji
Keyword(s):  
Drug Release ◽  
Transient Absorption ◽  
Gold Nanocages ◽  
Triggered Drug Release
Sign in / Sign up

Export Citation Format

Share Document