Synthesis, Structural Characterization, Protein Binding, DNA Cleavage and Anticancer Activity of Fluorophore Labelled Copper(II) Complexes Based on 1,8-Naphthalimide Conjugate

2021 ◽  
Author(s):  
Sabiha Shaikh ◽  
Satish Shantaram Bhat ◽  
Vidyanand K Revankar ◽  
Pooja Lokesh Hedge ◽  
Anup N. Kate ◽  
...  
Keyword(s):  
Protein Binding ◽  
Anticancer Activity ◽  
Structural Characterization ◽  
Dna Cleavage

The two novel fluorophore labelled copper(II) complexes [Cu(L)2(DMF)Cl2] (1) and [Cu(phen)(L)Cl2] (2), (Where, L = N-(3-pyridyl)-1, 8-naphthalimide, phen = 1,10- phenanthroline, DMF = dimethylformamide) incorporating fluorophore N-(3-pyridyl)-1, 8-naphthalimide and 1,10-phenanthroline...

Fluorophore Tagged Mixed Ligand Copper(II) Complexes: Synthesis, Structural Characterization, Protein Binding, DNA Cleavage and Anticancer Activity

2021 ◽  
Vol 6 (45) ◽  
pp. 12666-12676
Author(s):  
Sabiha A. Shaikh ◽  
Satish S. Bhat ◽  
Vidyanand K. Revankar ◽  
Badarinath D. Kulkarni ◽  
Karthik Kumara ◽  
...  
Keyword(s):  
Protein Binding ◽  
Anticancer Activity ◽  
Structural Characterization ◽  
Dna Cleavage ◽  
Mixed Ligand

Synthesis, DNA/protein binding, molecular docking, DNA cleavage and in vitro anticancer activity of nickel(ii) bis(thiosemicarbazone) complexes

RSC Advances ◽  
2015 ◽  
Vol 5 (57) ◽  
pp. 46031-46049 ◽  
Author(s):  
Jebiti Haribabu ◽  
Kumaramangalam Jeyalakshmi ◽  
Yuvaraj Arun ◽  
Nattamai S. P. Bhuvanesh ◽  
Paramasivan Thirumalai Perumal ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Protein Binding ◽  
Anticancer Activity ◽  
Dna Cleavage ◽  
Docking Studies ◽  
Molecular Docking Studies ◽  
Thiosemicarbazone Complexes ◽  
Ct Dna

Cytotoxic nickel(ii) complexes with an N-substituted isatin thiosemicarbazone were synthesized and their interaction with CT DNA and BSA protein was investigated, which was supported by molecular docking studies.

Mixed-Ligand Copper(II)-phenolate Complexes:  Effect of Coligand on Enhanced DNA and Protein Binding, DNA Cleavage, and Anticancer Activity

2007 ◽  
Vol 46 (20) ◽  
pp. 8208-8221 ◽  
Author(s):  
Venugopal Rajendiran ◽  
Ramasamy Karthik ◽  
Mallayan Palaniandavar ◽  
Helen Stoeckli-Evans ◽  
Vaiyapuri Subbarayan Periasamy ◽  
...  
Keyword(s):  
Protein Binding ◽  
Anticancer Activity ◽  
Dna Cleavage ◽  
Mixed Ligand

Synthesis, Electronic Structure, DNA and Protein Binding, DNA Cleavage, and Anticancer Activity of Fluorophore-Labeled Copper(II) Complexes

2011 ◽  
Vol 50 (2) ◽  
pp. 545-558 ◽  
Author(s):  
Satish S. Bhat ◽  
Anupa A. Kumbhar ◽  
Hussain Heptullah ◽  
Ayesha A. Khan ◽  
Vivekanand V. Gobre ◽  
...  
Keyword(s):  
Electronic Structure ◽  
Protein Binding ◽  
Anticancer Activity ◽  
Dna Cleavage

Novel N-heterocyclic carbene silver(I) complexes: Synthesis, structural characterization, and anticancer activity

2019 ◽  
Vol 486 ◽  
pp. 711-718 ◽  
Author(s):  
Serap Şahin-Bölükbaşı ◽  
Neslihan Şahin ◽  
Muhammad Nawaz Tahir ◽  
Cengiz Arıcı ◽  
Esranur Çevik ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Structural Characterization

An investigation on the DNA/protein binding, DNA cleavage and in vitro anticancer properties of SNO pincer type palladium(II) complexes with N-substituted isatin thiosemicarbazone ligands

2017 ◽  
Vol 466 ◽  
pp. 61-70 ◽  
Author(s):  
Mathiyan Muralisankar ◽  
Sabeel M. Basheer ◽  
Jebiti Haribabu ◽  
Nattamai S.P. Bhuvanesh ◽  
Ramasamy Karvembu ◽  
...  
Keyword(s):  
Protein Binding ◽  
Dna Cleavage ◽  
Anticancer Properties
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