Development of a novel reinforced film based on Gellan gum/Cellulose nanofiber/Soy protein for skin tissue engineering application

2021 ◽  
Author(s):  
Zahra Mohebian ◽  
Leila Yavari Maroufi ◽  
Marjan Ghorbani
Keyword(s):  
Tissue Engineering ◽  
Soy Protein ◽  
Nanocomposite Film ◽  
Composite Films ◽  
Engineering Application ◽  
Gellan Gum ◽  
Cellulose Nanofiber ◽  
Tissue Engineering Application ◽  
Skin Tissue Engineering ◽  
Potential Applications

Recently, the importance of biocompatible nanocomposite film with suitable properties has been further attracted for potential applications in the biomedical area. In this study, composite films of Gellan gum/Soy Protein/Cellulose...

scholarly journals 3D-Printed Biopolymers for Tissue Engineering Application

2014 ◽  
Vol 2014 ◽  
pp. 1-13 ◽  
Author(s):  
Xiaoming Li ◽  
Rongrong Cui ◽  
Lianwen Sun ◽  
Katerina E. Aifantis ◽  
Yubo Fan ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
3D Printing ◽  
Three Dimensional ◽  
Engineering Application ◽  
Tissue Engineering Application ◽  
Printing Technology ◽  
3D Printing Technology ◽  
Potential Applications ◽  
3D Printed ◽  
Dimensional Object

3D printing technology has recently gained substantial interest for potential applications in tissue engineering due to the ability of making a three-dimensional object of virtually any shape from a digital model. 3D-printed biopolymers, which combine the 3D printing technology and biopolymers, have shown great potential in tissue engineering applications and are receiving significant attention, which has resulted in the development of numerous research programs regarding the material systems which are available for 3D printing. This review focuses on recent advances in the development of biopolymer materials, including natural biopolymer-based materials and synthetic biopolymer-based materials prepared using 3D printing technology, and some future challenges and applications of this technology are discussed.

scholarly journals Preparation and Characterization of Sodium Alginate Polymeric Scaffold by Electrospinning Method for Skin Tissue Engineering Application

2021 ◽  
Author(s):  
Sorour Jadbabaei ◽  
Farid Naiemi ◽  
Hassan Ebadi-Dehaghani ◽  
Majid Kolahdoozan
Keyword(s):  
Tissue Engineering ◽  
Sodium Alginate ◽  
Engineering Application ◽  
L929 Cell ◽  
Skin Tissue ◽  
Tissue Engineering Application ◽  
Skin Tissue Engineering ◽  
Working Space ◽  
Polymeric Scaffold ◽  
High Viability

Abstract Sodium alginate (SA) approved its high potential in tissue engineering and regenerative medicine. One of the main weaknesses of this polysaccharide is its low spinnability which nanofiber based scaffolds are the interest of scientists in biomedical engineering. The main aim of this study was to improve the spinnability of SA in combination with polyvinyl alcohol (PVA). It was also tried to optimize the main parameters in electrospinning of the optimized SA;PVA ratio including voltage, flow rate, and working space. To aim this, Response surface methodology under central composite design was employed to design the experiments scientifically. The final nanofiber scaffolds were studied using scanning electron microscopy, Fourier transform infrared spectroscopy, degradability, swelling, tensile strength, porosity, nanofiber diameter, contact angle, and cytotoxicity. Based on the results, the best ratio for SA:PVA was 1:6.5. The solution with this concentration was spinnable in various values for the process parameters. The fabricated scaffolds under these conditions revealed good physical, chemical, mechanical, and biological features. L929 cell lines revealed high viability during 48 h of culture. The results revealed the uniform and homogeneous nanofibers with the regular size distribution (166 nm) were obtained at 30 kV, 0.55 µl/h, and 12.5 cm. To sum up, the optimized ratio under the reported conditions can be a good biologically compatible candidate for skin tissue engineering.

scholarly journals Skin Tissue Engineering: Application of Adipose-Derived Stem Cells

2017 ◽  
Vol 2017 ◽  
pp. 1-12 ◽  
Author(s):  
Agnes S. Klar ◽  
Jakub Zimoch ◽  
Thomas Biedermann
Keyword(s):  
Tissue Engineering ◽  
Stem Cells ◽  
Stem Cell ◽  
Engineering Application ◽  
Stromal Vascular Fraction ◽  
Skin Tissue ◽  
Tissue Engineering Application ◽  
Adipose Derived Stem Cells ◽  
Skin Tissue Engineering ◽  
Stem Cell Source

Perception of the adipose tissue has changed dramatically over the last few decades. Identification of adipose-derived stem cells (ASCs) ultimately transformed paradigm of this tissue from a passive energy depot into a promising stem cell source with properties of self-renewal and multipotential differentiation. As compared to bone marrow-derived stem cells (BMSCs), ASCs are more easily accessible and their isolation yields higher amount of stem cells. Therefore, the ASCs are of high interest for stem cell-based therapies and skin tissue engineering. Currently, freshly isolated stromal vascular fraction (SVF), which may be used directly without any expansion, was also assessed to be highly effective in treating skin radiation injuries, burns, or nonhealing wounds such as diabetic ulcers. In this paper, we review the characteristics of SVF and ASCs and the efficacy of their treatment for skin injuries and disorders.

Fabrication and characterization of a collagen coated electrospun poly(3-hydroxybutyric acid)–gelatin nanofibrous scaffold as a soft bio-mimetic material for skin tissue engineering applications

RSC Advances ◽  
2016 ◽  
Vol 6 (10) ◽  
pp. 7914-7922 ◽  
Author(s):  
Giriprasath Ramanathan ◽  
Sivakumar Singaravelu ◽  
M. D. Raja ◽  
Naveen Nagiah ◽  
P. Padmapriya ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Engineering Application ◽  
Nanofibrous Scaffold ◽  
Skin Tissue ◽  
Tissue Engineering Application ◽  
Hydroxybutyric Acid ◽  
Skin Tissue Engineering ◽  
Promising Tool ◽  
Good Biocompatibility

The collagen coated nanofibrous scaffold mimics the function of the extra cellular matrix with good biocompatibility, cell adhesion, cell proliferation and aids to provide as a promising tool in skin tissue engineering application.

Role of Block Copolymers in Tissue Engineering Applications

2021 ◽  
pp. 1-14
Author(s):  
Sairish Malik ◽  
Subramanian Sundarrajan ◽  
Tanveer Hussain ◽  
Ahsan Nazir ◽  
Seeram Ramakrishna
Keyword(s):  
Tissue Engineering ◽  
Block Copolymers ◽  
Microphase Separation ◽  
High Surface ◽  
Engineering Application ◽  
Volume Ratio ◽  
Tissue Engineering Application ◽  
Electrospinning Technique ◽  
Potential Applications ◽  
Broad Variety

Research on synthesis, characterization, and understanding of novel properties of nanomaterials has led researchers to exploit their potential applications. When compared to other nanotechnologies described in the literature, electrospinning has received significant interest due to its ability to synthesize novel nanostructures (such as nanofibers, nanorods, nanotubes, etc.) with distinctive properties such as high surface-to-volume ratio, porosity, various morphologies such as fibers, tubes, ribbons, mesoporous and coated structures, and so on. Various materials such as polymers, ceramics, and composites have been fabricated using the electrospinning technique. Among them, polymers, especially block copolymers, are one of the useful and niche systems studied recently owing to their unique and fascinating properties in both solution and solid state due to thermodynamic incompatibility of the blocks, that results in microphase separation. Morphology and mechanical properties of electrospun block copolymers are intensely influenced by quantity and length of soft and hard segments. They are one of the best studied systems to fit numerous applications due to a broad variety of properties they display upon varying the composition ratio and molecular weight of blocks. In this review, the synthesis, fundamentals, electrospinning, and tissue engineering application of block copolymers are highlighted.

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