Copper(II) Complexes of 2-methyl-8-hydroxyquinoline and tri/diimine Co-ligand: DFT Calculation, DNA and BSA Binding, DNA Cleavage, Cytotoxicity and Induction of Apoptosis

2021 ◽  
Author(s):  
Sangeetha Somasundaram ◽  
Tamilarasan Ajaykamal ◽  
Murali Mariappan
Keyword(s):  
Crystal Structure ◽  
Dna Cleavage ◽  
Dft Calculation ◽  
Mixed Ligand ◽  
Bsa Binding ◽  
Induction Of Apoptosis

The mixed ligand copper(II) complexes [Cu(terpy)(mq)]ClO4 (1) and [Cu(phen)(mq)]ClO4 (2), where terpy = 2,2’:6’,2’’-terpyridine, phen = 1,10-phenanthroline and H(mq) = 2-methyl-8-hydroxyquinoline have been synthesised. The crystal structure of 1 discloses...

Cytotoxic copper (II) mixed ligand complexes: Crystal structure and DNA cleavage activity

2011 ◽  
Vol 46 (9) ◽  
pp. 4537-4547 ◽  
Author(s):  
Verasuntharam M. Manikandamathavan ◽  
Royapuram P. Parameswari ◽  
Thomas Weyhermüller ◽  
Hannah R. Vasanthi ◽  
Balachandran Unni Nair
Keyword(s):  
Crystal Structure ◽  
Dna Cleavage ◽  
Mixed Ligand ◽  
Mixed Ligand Complexes ◽  
Cleavage Activity ◽  
Dna Cleavage Activity

Four related mixed-ligand nickel(ii) complexes: effect of steric encumbrance on the structure, DNA/BSA binding, DNA cleavage and cytotoxicity

RSC Advances ◽  
2015 ◽  
Vol 5 (39) ◽  
pp. 30768-30779 ◽  
Author(s):  
Chun-Yan Gao ◽  
Zhong-Ying Ma ◽  
Yong-Po Zhang ◽  
Si-Tong Li ◽  
Wen Gu ◽  
...  
Keyword(s):  
Dna Binding ◽  
Dna Cleavage ◽  
Mixed Ligand ◽  
Bsa Binding

Four new interrelated mixed-ligand nickel(ii) complexes have been synthesized and characterized. The activities of DNA binding/cleavage, BSA binding with complexes and the vitro cytotoxicity also have been explored.

Mixed-ligand manganese(II)-phenolate complexes: study of DNA cleavage, cytotoxic activity, and induction of apoptosis

2011 ◽  
Vol 64 (22) ◽  
pp. 3992-4005 ◽  
Author(s):  
En-Jun Gao ◽  
Ying Zhang ◽  
Lin Lin ◽  
Ren-Shu Wang ◽  
Lei Dai ◽  
...  
Keyword(s):  
Cytotoxic Activity ◽  
Dna Cleavage ◽  
Mixed Ligand ◽  
Induction Of Apoptosis

Synthesis, characterization, X-ray crystal structure, DFT calculation, DNA binding, and antimicrobial assays of two new mixed-ligand copper(II) complexes

2015 ◽  
Vol 142 ◽  
pp. 410-422 ◽  
Author(s):  
S. Yousef Ebrahimipour ◽  
Iran Sheikhshoaie ◽  
Maryam Mohamadi ◽  
Sebastian Suarez ◽  
Ricardo Baggio ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Dna Binding ◽  
Dft Calculation ◽  
Mixed Ligand ◽  
X Ray

Synthesis, X-ray crystal structure, DNA/BSA binding, DNA cleavage and cytotoxicity studies of phenanthroline based copper(II)/zinc(II) complexes

BioMetals ◽  
2017 ◽  
Vol 30 (4) ◽  
pp. 575-587 ◽  
Author(s):  
Qingming Wang ◽  
Han Mao ◽  
Wenling Wang ◽  
Huimin Zhu ◽  
Lihui Dai ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Dna Cleavage ◽  
X Ray ◽  
Bsa Binding ◽  
Cytotoxicity Studies

Synthesis, Crystal Structure And Spectroscopic Studies Of A Mixed Ligand Copper (Ii) Complex: Trans-Bis(Succinimidato)-Bis(Benzylamino)Cu(Ii)

2006 ◽  
Vol 61 (8) ◽  
pp. 979-982 ◽  
Author(s):  
Murat Taş ◽  
Hanife Saraçoğlu ◽  
Hümeyra Bati ◽  
Nezihe Çalışkan ◽  
Orhan Büyükgüngör
Keyword(s):  
Crystal Structure ◽  
Hydrogen Bonds ◽  
Title Compound ◽  
Spectroscopic Studies ◽  
Mixed Ligand ◽  
Interplanar Angle ◽  
Space Group ◽  
Square Planar

The molecules of the title compound, [Cu(C11H13N2O2)2], lie across centres of inversion in space group P21/c and are linked by intermolecular N-H···O and C-H···O hydrogen bonds. The central Cu atom has a slightly distorted square-planar coordination comprised of four N atoms. Cu-N bond distances are 1.975(2) and 2.020(2) Å . The interplanar angle between the phenyl and succinimidato ring is 87.34(10)°

Synthesis, characterization, antimicrobial, BSA binding, DFT calculation, molecular docking and cytotoxicity of Ni(II) complexes with Schiff base ligands

2021 ◽  
Vol 328 ◽  
pp. 115457
Author(s):  
J. Jeevitha Rani ◽  
A. Mary Imelda Jayaseeli ◽  
S. Rajagopal ◽  
S. Seenithurai ◽  
Jeng-Da Chai ◽  
...  
Keyword(s):  
Schiff Base ◽  
Molecular Docking ◽  
Dft Calculation ◽  
Schiff Base Ligands ◽  
Bsa Binding
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