scholarly journals Molecular trace detection in liquids using refocusing optical feedback by a silver-coated capillary

2021 ◽  
Author(s):  
Chen Kang ◽  
Zhoutao Sun ◽  
Xiaohui Fang ◽  
Lei Zha ◽  
Yu Han ◽  
...  

3-dimensional surface-enhanced Raman scattering (SERS) platforms greatly extend the interaction area and ensure the ability to directly detect trace amounts of molecules in liquids. Silver-coated capillary, with the ability of...

2015 ◽  
Vol 7 (9) ◽  
pp. 3863-3868 ◽  
Author(s):  
Arniza K. M. Jamil ◽  
Emad L. Izake ◽  
Arumugam Sivanesan ◽  
Roland Agoston ◽  
Godwin A. Ayoko

Extraction and SERS detection of TNT in soil.


2019 ◽  
Vol 55 (59) ◽  
pp. 8647-8650 ◽  
Author(s):  
Meihong Ge ◽  
Pan Li ◽  
Chentai Cao ◽  
Shaofei Li ◽  
Dongyue Lin ◽  
...  

A simple and effective method to construct a long-period and high-stability 3D hotspot matrix with the assistance of glycerol.


2020 ◽  
Vol 74 (11) ◽  
pp. 1374-1383
Author(s):  
Jacob E. Olson ◽  
Adam S. Braegelman ◽  
Lei Zou ◽  
Matthew J. Webber ◽  
Jon P. Camden

The cucurbit[n]uril (CB[ n]) family of macrocycles are known to bind a variety of small molecules with high affinity. These motifs thus have promise in an ever-growing list of trace detection methods. Surface-enhanced Raman scattering (SERS) detection schemes employing CB[ n] motifs exhibit increased sensitivity due to selective concentration of the analyte at the nanoparticle surface, coupled with the ability of CB[ n] to facilitate the formation of well-defined electromagnetic hot spots. Herein, we report a CB[7] SERS assay for quantification of phenylalanine (Phe) and further demonstrate its utility for detecting peptides with an N-terminal Phe. The CB[7]–guest interaction improves the sensitivity 5–25-fold over direct detection of Phe using citrate-capped silver nanoparticle aggregates, enabling use of a portable Raman system. We further illustrate detection of insulin via binding of CB[7] to the N-terminal Phe residue on its B-chain, suggesting a general strategy for detecting Phe-terminated peptides of clinically relevant biomolecules.


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