scholarly journals Estimating the cooperativity of PROTAC-induced ternary complexes using 19F NMR displacement assay

2021 ◽  
Author(s):  
Guilherme Castro ◽  
Alessio Ciulli
Keyword(s):  
Ternary Complexes ◽  
19F Nmr ◽  
Fluorine Nmr ◽  
Competition Binding ◽  
Displacement Assay

Cooperativity is an important parameter to understand the ternary complexes formed by protein degraders. We developed fluorine NMR competition binding experiments to determine cooperativity of PROTACs. We show applicability to...

scholarly journals Correction: Estimating the cooperativity of PROTAC-induced ternary complexes using 19F NMR displacement assay

2022 ◽  
Author(s):  
Guilherme Vieira de Castro ◽  
Alessio Ciulli
Keyword(s):  
Ternary Complexes ◽  
19F Nmr ◽  
Displacement Assay

Correction for ‘Estimating the cooperativity of PROTAC-induced ternary complexes using 19F NMR displacement assay’ by Guilherme Vieira de Castro et al., RSC Med. Chem., 2021, 12, 1765–1770, DOI: 10.1039/D1MD00215E.

scholarly journals 19F NMR indicator displacement assay using a synthetic receptor with appended paramagnetic relaxation agent

2014 ◽  
Vol 50 (72) ◽  
pp. 10499-10501 ◽  
Author(s):  
Adam J. Plaunt ◽  
Kasey J. Clear ◽  
Bradley D. Smith
Keyword(s):  
Signal Intensity ◽  
Paramagnetic Relaxation ◽  
19F Nmr ◽  
Synthetic Receptor ◽  
Displacement Assay

A 19F NMR indicator displacement assay detects phosphorylated analytes with amplified signal intensity.

Use of 19F NMR for studies of the complexation of gallium (III) by 5-fluoro-8-hydroxyquinoline

1998 ◽  
Vol 95 (2) ◽  
pp. 395-400
Author(s):  
O. Jarjayes ◽  
S. Hamman ◽  
C. G. Beguin
Keyword(s):  
19F Nmr
Sign in / Sign up

Export Citation Format

Share Document