scholarly journals Effect of solvation on the synthesis of MOFs-based micro/nanorobots and its targeted-therapy applications

2021 ◽  
Author(s):  
Xueliang Mu ◽  
Yukun Zhong ◽  
Teng Jiang ◽  
U Kei Cheang
Keyword(s):  
Drug Delivery ◽  
Targeted Therapy ◽  
Significant Influence ◽  
Potential Risk ◽  
Targeted Drug Delivery ◽  
Biological Toxicity ◽  
Targeted Drug

Magnetically-driven mobile micro/nanorobots have a significant influence on the application and development of intelligent targeted drug delivery. However, the potential risk of biological toxicity is one of the major main...

Design and synthesis of aptamer AS1411-conjugated EG@TiO2@Fe2O3 nanoparticles as a drug delivery platform for tumor-targeted therapy

2020 ◽  
Vol 44 (37) ◽  
pp. 15871-15886 ◽  
Author(s):  
Nahid Mansouri ◽  
Razieh Jalal ◽  
Batool Akhlaghinia ◽  
Khalil Abnous ◽  
Roya Jahanshahi
Keyword(s):  
Drug Delivery ◽  
Targeted Therapy ◽  
Sustained Release ◽  
Targeted Drug Delivery ◽  
Fe2o3 Nanoparticles ◽  
Ph Responsive ◽  
Release System ◽  
Design And Synthesis ◽  
Delivery Platform ◽  
Targeted Drug

AS1411@GMBS@EG@TiO2@Fe2O3 nanoparticle is an effective and safe pH-responsive sustained release system for targeted drug delivery into nucleolin-positive cells.

scholarly journals Functional Nanomedicines for Targeted Therapy of Bladder Cancer

2021 ◽  
Vol 12 ◽  
Author(s):  
Chao Tang ◽  
Heng Liu ◽  
Yanpeng Fan ◽  
Jiahao He ◽  
Fuqiu Li ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Bladder Cancer ◽  
Targeted Therapy ◽  
Targeted Drug Delivery ◽  
Drug Efficacy ◽  
Intravesical Instillation ◽  
Frequent Administration ◽  
Long Time ◽  
Targeted Drug ◽  
Muscle Invasive

Bladder cancer is one of most common malignant urinary tract tumor types with high incidence worldwide. In general, transurethral resection of non-muscle-invasive bladder cancer followed by intravesical instillation of chemotherapy is the standard treatment approach to minimize recurrence and delay progression of bladder cancer. However, conventional intravesical chemotherapy lacks selectivity for tumor tissues and the concentration of drug is reduced with the excretion of urine, leading to frequent administration and heavy local irritation symptoms. While nanomedicines can overcome all the above shortcomings and adhere to the surface of bladder tumors for a long time, and continuously and efficiently release drugs to bladder cancers. The rapid advances in targeted therapy have led to significant improvements in drug efficacy and precision of targeted drug delivery to eradicate tumor cells, with reduced side-effects. This review summarizes the different available nano-systems of targeted drug delivery to bladder cancer tissues. The challenges and prospects of targeted therapy for bladder cancer are additionally discussed.

Sign in / Sign up

Export Citation Format

Share Document