A turn-on fluorescent sensing strategy for rapid detection of Flumequine in water environment using covalent-coordination functionalized MOFs

CrystEngComm ◽  
2021 ◽  
Author(s):  
Shengnan Li ◽  
Ying Li ◽  
Bing Yan
Keyword(s):  
Rapid Detection ◽  
Water Environment ◽  
Fluorescent Sensing ◽  
Turn On ◽  
High Output

With the high output and large use of antibiotics in the process of aquaculture, the pollution caused by antibiotics in water environment is becoming a thorny problem, and its ecological...

scholarly journals A Bioluminescent Sensor for Rapid Detection of PPEP-1, a Clostridioides difficile Biomarker

Sensors ◽  
2021 ◽  
Vol 21 (22) ◽  
pp. 7485
Author(s):  
Kevin K. Ng ◽  
Zachary E. Reinert ◽  
Jeroen Corver ◽  
Danica Resurreccion ◽  
Paul J. Hensbergen ◽  
...  
Keyword(s):  
Ambient Temperature ◽  
Rapid Detection ◽  
Point Of Care ◽  
Delayed Diagnosis ◽  
Digital Camera ◽  
Proteolytic Cleavage ◽  
Fecal Material ◽  
Turn On ◽  
Clostridioides Difficile ◽  
Specific Protease

Current assays for Clostridioides difficile in nonhospital settings are outsourced and time-intensive, resulting in both delayed diagnosis and quarantining of infected individuals. We designed a more rapid point-of-care assay featuring a “turn-on” bioluminescent readout of a C. difficile-specific protease, PPEP-1. NanoLuc, a bright and stable luciferase, was “caged” with a PPEP-1-responsive peptide tail that inhibited luminescence. Upon proteolytic cleavage, the peptide was released and NanoLuc activity was restored, providing a visible readout. The bioluminescent sensor detected PPEP-1 concentrations as low as 10 nM. Sensor uncaging was achieved within minutes, and signal was captured using a digital camera. Importantly, the sensor was also functional at ambient temperature and compatible with fecal material, suggesting that it can be readily deployed in a variety of settings.

scholarly journals A New Fluorescence Probe for Rapid Detection of Amyloid

2018 ◽  
Author(s):  
Nidhi Gour ◽  
Vivek Shinh Kshtriya ◽  
Bharti Koshti ◽  
Shradhey Gupta ◽  
khashti Ballabh Joshi ◽  
...  
Keyword(s):  
Rapid Detection ◽  
Control Experiment ◽  
Fluorescence Probe ◽  
Photophysical Properties ◽  
Cost Effective ◽  
The Novel ◽  
High Quantum Yield ◽  
Turn On ◽  
Heat Treated ◽  
Amyloidogenic Peptides

<p>We report efficient synthesis and photophysical properties of a novel fluorescent pyridothiazole based construct by a facile methodology and its application as a sensor for rapid, selective as well as sensitive detection of amyloid fibres. The novel compound has exceptionally high quantum yield and sensitivity. The fluorescence of pyridothiazole construct is completely quenched (Turn-OFF) upon addition of cupric ions and the fluorescence is recovered on addition of amyloidogenic peptides like A<i>β</i><sub>42 </sub>(Turn-ON). The control experiment with native and heat treated BSA suggest that the new probe binds to beeta/<i>β</i> sheets present in amyloid. The new probe offers direct visualization of fluorescence ‘Turn-OFF’ ‘Turn-ON’ under long UV without the use of sophisticated instrumentation. Hence, a very simple, facile and cost-effective methodology for the rapid detection of amyloid is presented and it may in all possibility pave the way for the design of a better probe for sensing amyloids than conventional ThT.</p>

A Ca2+ controlled thioether linked bichromophoric squaraine foldamer for “turn on” fluorescent sensing of oxalate

2015 ◽  
Vol 206 ◽  
pp. 624-629 ◽  
Author(s):  
Guimei Wang ◽  
Huijun Zhu ◽  
Yaohui Lin ◽  
Yaqing Chen ◽  
Nanyan Fu
Keyword(s):  
Fluorescent Sensing ◽  
Turn On

“Reactive” probe for fluoride: “Turn-on” fluorescent sensing in aqueous solution and bioimaging in living cells

2014 ◽  
Vol 199 ◽  
pp. 54-61 ◽  
Author(s):  
Xiaohong Cheng ◽  
Huizhen Jia ◽  
Jun Feng ◽  
Jingui Qin ◽  
Zhen Li
Keyword(s):  
Aqueous Solution ◽  
Living Cells ◽  
Fluorescent Sensing ◽  
Turn On

Analyte-Driven Disassembly and Turn-On Fluorescent Sensing in Competitive Biological Media

2018 ◽  
Vol 140 (10) ◽  
pp. 3500-3504 ◽  
Author(s):  
Meagan A. Beatty ◽  
Jorge Borges-González ◽  
Nicholas J. Sinclair ◽  
Aidan T. Pye ◽  
Fraser Hof
Keyword(s):  
Biological Media ◽  
Fluorescent Sensing ◽  
Turn On

Gold nanoclusters-based dual-channel assay for colorimetric and turn-on fluorescent sensing of alkaline phosphatase

2019 ◽  
Vol 301 ◽  
pp. 127080 ◽  
Author(s):  
Pengjuan Ni ◽  
Chuanxia Chen ◽  
Yuanyuan Jiang ◽  
Chenghui Zhang ◽  
Bo Wang ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Gold Nanoclusters ◽  
Fluorescent Sensing ◽  
Turn On ◽  
Dual Channel

A Turn‐On Fluorescence Probe for Rapid Detection of Hypochlorite in Living Cells and in Vitro

2019 ◽  
Vol 4 (27) ◽  
pp. 8021-8025 ◽  
Author(s):  
Ya Xie ◽  
Lijia Haung ◽  
Liqiang Yan ◽  
Jianping Li
Keyword(s):  
Rapid Detection ◽  
Fluorescence Probe ◽  
Living Cells ◽  
Turn On

A turn-on fluorescent probe for hypochlorous acid based on the oxidation of diphenyl telluride

The Analyst ◽  
2015 ◽  
Vol 140 (4) ◽  
pp. 1349-1355 ◽  
Author(s):  
Parthiban Venkatesan ◽  
Shu-Pao Wu
Keyword(s):  
Fluorescent Probe ◽  
Rapid Detection ◽  
Hypochlorous Acid ◽  
Turn On

A fluorescent probe HCTe was developed for rapid detection of hypochlorous acid based on the specific HOCl-promoted oxidation of diphenyl telluride.

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